Tetrapyrroles and derivatives
Medchemexpress LLC Cyanocobalamin (Vitamin B12 Standard) | 68-19-9 | 99.95% | 100 MG
Vitamin B12 (Standard) is the analytical standard of Vitamin B12. This product is intended for research and analytical applications. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
- Analytical standard for research and analytical applications
- Supports normal functioning of the brain and nervous system
- Essential for the formation of blood
- Suitable as a reference standard in HPLC, GC, and MS experiments
Apexbio Technology LLC Tin protoporphyrin IX dichloride(Synonyms: Tin Protoporphyrin Dichloride, SnPP, SnPP IX, Tin(IV) Protoporphyrin Dichloride), 10mg, CAS: 14325-05-4.
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways
Sigma Aldrich Fine Chemicals Biosciences meso-Tetraphenylporphyrin BioReagent, suitable for fluorescence, >=99.0% (HPLC) | 917-23-7 | MFCD00011680 | 1G
meso-Tetraphenylporphyrin BioReagent, suitable for fluorescence, >=99.0% (HPLC) | Purity: >=99.0% (HPLC) | Mol Wt: 614.74 | 917-23-7 | MFCD00011680 | 1G
Medchemexpress LLC Methylcobalamin | 13422-55-4 | 99.0% | 1 ML
Methylcobalamin, a cobalamin and form of vitamin B12, is characterized by a methyl group replacing the cyanide found in cyanocobalamin. This compound features an octahedral cobalt(III) centre and is known for its rare metal-alkyl bonds. Physiologically, it functions as vitamin B12, addressing deficiencies such as pernicious anemia, and is also applied in treating peripheral neuropathy, diabetic neuropathy, and amyotrophic lateral sclerosis.
- Form of vitamin B12 (cobalamin)
- Contains a methyl group instead of cyanide
- Features an octahedral cobalt(III) centre and metal-alkyl bonds
- Equivalent to vitamin B12 for treating deficiencies (e.g., pernicious anemia)
- Used in peripheral neuropathy, diabetic neuropathy, and amyotrophic lateral sclerosis treatment
Abcam AMD3100 octahydrochloride, C x CR4 antagonist, 5MG
MW 794.5 Da, Purity >99%. Plerixafor (hydrochloride) is a macrocyclic compound that acts as an irreversible antagonist against the binding of CXCR4 with its ligand, SDF-1 (CXCL12). It suppresses infection by HIV with an IC₅₀ value of 1-10 ng/ml with selectivity toward CXCR4-tropic virus. Plerixafor mobilizes hematopoietic stem and progenitor cells for transplant better than G-CSF alone. It also increases T-cell trafficking in the blood and spleen as well as the central nervous system. Plerixafor regulates the growth of primary and metastic breast cancer cells and inhibits dissemination of ovarian carcinoma cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AMD3100 octahydrochloride, C x CR4 antagonist, 10MG
MW 794.5 Da, Purity >99%. Plerixafor (hydrochloride) is a macrocyclic compound that acts as an irreversible antagonist against the binding of CXCR4 with its ligand, SDF-1 (CXCL12). It suppresses infection by HIV with an IC₅₀ value of 1-10 ng/ml with selectivity toward CXCR4-tropic virus. Plerixafor mobilizes hematopoietic stem and progenitor cells for transplant better than G-CSF alone. It also increases T-cell trafficking in the blood and spleen as well as the central nervous system. Plerixafor regulates the growth of primary and metastic breast cancer cells and inhibits dissemination of ovarian carcinoma cells.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Protoporphyrin IX disodium | 50865-01-5 | 96.5% | 606.62 | C34H32N4Na2O4 | 10 MG
Protoporphyrin IX disodium is the disodium salt of protoporphyrin IX, supplied for laboratory research including studies of heme biosynthesis and photodynamic or sonodynamic therapy. It is provided as a solid with analytical documentation to support research use.
- CAS number 50865-01-5
- Molecular formula C34H32N4Na2O4
- Molecular weight 606.62
- Purity 96.5%
- Appearance solid, brown to black
- Available in small research quantities, including 10 MG
- Documentation available: SDS and COA
Sigma Aldrich Fine Chemicals Biosciences Hemin | 16009-13-5 | MFCD00010726 | 1g
Hemin | Purity: 90% | Mol Wt: 651.94 | 16009-13-5 | MFCD00010726 | 1g
Abcam DPDPE, delta opioid receptor agonist, 5MG
MW 645.79 g/mol, Purity >95%. Potent and selective δ opioid receptor agonist (Ki values are 14, >1000 and >1000 nM for opioid receptor subtypes δ, κ and μ, respectively). Centrally active following systemic administration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Rotigotine hydrochloride, Dopamine receptor agonist, 50MG
MW 351.93 g/mol, Purity >99%. Dopamine receptor agonist. High affinity for D₁, D₂ and D₃ receptors (Ki values are 83, 13 and 0.71 nM, respectively). Shows significant affinity at α₂B and 5-HT₁A receptors (Ki values are 27 and 30 nM, respectively). Exhibits anti-Parkinsonian and antidepressant activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 216641 hydrochloride, h5-HT1B antagonist, 10MG
MW 523.03 g/mol, Purity >98%. Selective h5-HT₁B receptor antagonist. 25-fold selectivity over h5-HT₁D. Little or no affinity for a range of other receptor subtypes.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 50mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Abcam GS 39783, GABAB positive allosteric modulator, 10MG
MW 337.4 Da, Purity >99%. Novel, GABAB positive allosteric modulator (EC50 = 3 μM for [35S]GTPγS binding). Shows anxiolytic and antiaddictive effects *in vivo.* Blood-brain barrier permeable*.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DPDPE, delta opioid receptor agonist, 1MG
MW 645.79 g/mol, Purity >95%. Potent and selective δ opioid receptor agonist (Ki values are 14, >1000 and >1000 nM for opioid receptor subtypes δ, κ and μ, respectively). Centrally active following systemic administration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pancuronium dibromide, Competitive nicotinic acetylcholine receptor antagonist, 50MG
MW 732.7 Da. Competitive nicotinic acetylcholine receptor (nAChR) antagonist. Displaces acetylcholine (ab120469) from nAChRs (IC₅₀ = 5.5 nM). Neuromuscular blocker and muscle relaxant.
The product is subject to the following: Abcam Restricted Use Statement