Tetrapyrroles and derivatives
Sigma Aldrich Fine Chemicals Biosciences HEMIN BIOXTRA, FROM PORCINE
Hemin BioXtra, from Porcine, ≥97.0% (HPLC)
Enzo Life Sciences Zinc(II) Protoporphyrin IX (25mg). CAS: 15442-64-5
Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter. Purity: ≥95% (TLC). Solubility: Soluble in pyridine, dimethyl formamide or DMSO. Colloidal in aqueous base; slightly soluble in aqueous base/organic solvent mixtures. Long Term Storage: -20°C.
Sigma Aldrich Fine Chemicals Biosciences Hemin BioXtra from Porcine5G
REAGENT Hemin BioXtra from Porcine5G
Medchemexpress LLC Protoporphyrin IX | 553-12-8 | MFCD00151109 | 98.0% | 100 MG
Protoporphyrin IX is an endogenous metabolite and a final intermediate in the heme biosynthetic pathway. It functions as a radiation sensitizer, enhancing ROS generation even in hypoxic conditions and inducing DNA damage. It also acts as a photosensitizer that undergoes photobleaching from light irradiation. It accumulates in tumor cells after administration of 5-aminolevulinic acid (5-ALA).
- Endogenous metabolite and final intermediate in heme biosynthetic pathway
- Functions as a radiation sensitizer
- Enhances ROS generation even in hypoxic conditions
- Induces DNA damage
- Acts as a photosensitizer that undergoes photobleaching from light irradiation
- Accumulates in tumor cells after administration of 5-aminolevulinic acid (5-ALA)
- Shows promise as a sonodynamic and photodynamic agent for various cancers, such as bladder cancer and nodular basal cell carcinoma
Sigma Aldrich Fine Chemicals Biosciences Cytochrome c from bovine heart | 9007-43-6 | MFCD00130890 | 500mg
Cytochrome c from bovine heart | Purity: ≥95% | Mol Wt: 12327 Da | 9007-43-6 | MFCD00130890 | 500mg
![eMolecules AstaTech / 1H-BENZO[D]AZEPIN-2(3H)-ONE / 0.25g / 256638974 / 32291 / 97.000 / 19301-09-8 / MFCD01101239 / 159.188 / C10H9NO](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502466756.JPG-250.jpg)
eMolecules AstaTech / 1H-BENZO[D]AZEPIN-2(3H)-ONE / 0.25g / 256638974 / 32291 / 97.000 / 19301-09-8 / MFCD01101239 / 159.188 / C10H9NO
AstaTech / 1H-BENZO[D]AZEPIN-2(3H)-ONE / 0.25g / 256638974 / 32291 / 97.000 / 19301-09-8 / MFCD01101239 / 159.188 / C10H9NO
Chem-Impex International, Inc. Hemin (from porcine) | 16009-13-5 | MFCD00010726 | 1G
Hemin (from porcine), 16009-13-5, MFCD00010726, 1G
Enzo Life Sciences Protoporphyrin IX (free acid) (1g). CAS: 553-12-8
Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Alternative name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid. Purity: ≥95% (HPLC). Appearance: Purple to dark brown solid. Solubility: Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately. Long Term Storage: -20°C.
eMolecules Ambeed / Oxazol-2(3H)-one / 250mg / 491662683 / A367076 / / 27584-70-9 / MFCD00075369 / 85.062 / C3H3NO2
Ambeed / Oxazol-2(3H)-one / 250mg / 491662683 / A367076 / / 27584-70-9 / MFCD00075369 / 85.062 / C3H3NO2
Medchemexpress LLC Zinc protoporphyrin | 15442-64-5 | MFCD00011612 | 626.02 | C34H32N4O4Zn | 50 MG
Zinc protoporphyrin (Zn(II)-protoporphyrin IX) is a metalloporphyrin research reagent used as a competitive inhibitor of heme oxygenase-1 (HO-1) and as a biomarker in studies of iron deficiency. It is applied in biochemical and cellular assays to probe HO-1 activity and related pathways.
- Competitive heme oxygenase-1 (HO-1) inhibitor.
- Used as a biomarker for iron deficiency in vivo.
- Suitable for biochemical and cellular assays.
- Molecular formula C34H32N4O4Zn; molecular weight 626.02.
- Store at -20°C, sealed and protected from moisture; in solvent store at -80°C for long term.
Medchemexpress LLC Chlorin e6 (trisodium) | 72984-36-2 | 98.7% | 662.62 | C34H33N4Na3O6 | 25mg
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation enabling real-time identification of tumor boundaries and progression Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions[1][2][3]
Medchemexpress LLC Chlorin e6 trimethyl ester | 35038-32-5 | 99.8% | 638.75 | 25 MG
Chlorin e6 trimethyl ester is a methyl pheophorbide-a derivative functioning as a photosensitizer for photodynamic therapy (PDT). This solid, brown to black compound exhibits photo cytotoxic activity against human HepG2 cells and is intended for research use only.
- Used as a photosensitizer
- Applicable in photodynamic therapy (PDT)
- Exhibits photo cytotoxic activity
- Solid appearance with brown to black color
- Soluble in DMSO
Sigma Aldrich Fine Chemicals Biosciences Cytochrome c from equine heart | 9007-43-6 | MFCD00130890 | 5x1vl
Cytochrome c from equine heart | Mol Wt: 12400 | 9007-43-6 | MFCD00130890 | 5x1vl
Frontier Specialty Chemicals 1G MESO-TETRA(4-PYRIDYL)PORPHI
This item has a minimum qty of 4 per supplier requirements.
meso-Tetra(4-pyridyl)porphine; CAS: 16834-13-2; 1g