Tetrapyrroles and derivatives
Abcam SB431542, ALK inhibitor, 1MG
MW 384.4 Da, Purity >99%. Potent and selective inhibitor of Activin Like Kinase. Inhibits ALK 4, 5 (IC₅₀ = 94 nM), and 7.
The product is subject to the following: Abcam Restricted Use Statement
Abcam WAY-100635 maleate, 5-HT1A receptor antagonist, 10MG
MW 538.6 Da, Purity >98%. Potent, selective, silent 5-HT1A receptor antagonist (IC50 = 1.35 nM). Displays >100-fold selectivity for 5-HT1Arelative to a range of other CNS receptors including other 5-HT subtypes, adrenoceptors, dopamine, GABA, histamine and ion channels. Binds selectively to rodent brain 5-HT1A receptors *in vivo* (iv admin). Unlike WAY100135, WAY100635 displays no partial agonist activity in the ventral hippocampus of rats.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-Thiouridine, RNA synthesis inhibitor, 5MG
MW 260.27 Da, Purity >99%. Ribonucleoside (Uridine ab143255) analog. Antisense agent. RNA synthesis inhibitor. Modifies oligos slated for RNA. Induces p53 and inhibits proliferation. Metabolically labels RNA for stability studies.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cytochalasin D, actin polymerization inhibitor, 5MG
MW 507.6 Da, Purity >98%. Cytochalasin D, actin polymerization inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam GsMT x -4, mechanosensitive and stretch-activated ion channel inhibitor, 500UG
MW 4096 Da. GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 5-Aza-2'-deo x ycytidine (Decitabine), DNMT1 inhibitor, 25MG
MW 228.21 Da, Purity >99%. Potent DNA methyltransferase 1 (DNMT1) inhibitor (IC₅₀ = 0.2 μM). Incorporated into DNA, inhibits DNMT1 activity to induce DNA hypomethylation. Interferes with protein synthesis. Shows antimetabolic and anticancer activities in vitro. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Dihydrokainic acid, EAAT2 (GLT-1) inhibitor, 1MG
MW 215.25 Da. Selective, non-transportable inhibitor of glutamate transporter EAAT2 (GLT-1) (Ki = 23 μM). 130-fold selective over EAAT1 and EAAT3 (Ki > 3 mM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Rebo x etine mesylate, Noradrenaline reuptake inhibitor, 50MG
MW 409.5 Da, Purity >99%. Potent, selective noradrenaline reuptake inhibitor, with high selectivity over dopamine and 5-HT transporters. Antidepressant in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Nocodazole, Microtubule inhibitor, 50MG
MW 301.32 Da, Purity >98%. Microtubule inhibitor. Rapidly depolymerises microtubules in vivo and inhibits tubulin polymerisation in vitro. Inhibits mitosis. Also reduces stem cell pluripotency factors Oct 4 and Nanog.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Methylcobalamin, Purity: ≥98%, CAS: 13422-55-4, 1 g
An analog of vitamin B12 with diverse neurological activities; promotes neurite outgrowth and survival in primary CGN and DRG cells and activation of ERK1/2 and Akt from 0.1-100 µM; improves sensory function in a pinch test and increases toe spreading in a rat model of sciatic nerve injury at 1 mg/kg per day; decreases the number of atypical mitochondria in the sciatic nerve and reduces vincristine-induced mechanical allodynia and thermal hyperalgesia in a rat model of neuropathic pain; reduces muscle weakness and forelimb contracture and increases bicep muscle weight and the number of musculocutaneous nerves in the wobbler mouse model of ALS; enhances the recovery of compound muscle action potentials and motor end plate innervation and decreases the time to sticker removal in the sticker removal grooming test in a rat model of bicep ulnar to musculocutaneous nerve transfer
Abcam Endothelin-1 (human, porcine), Vasoconstrictor peptide, 500UG
MW 2491.9 Da. Endothelin-1 (human, porcine), Vasoconstrictor peptide. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Chem-Impex International, Inc. Hemin (from porcine) | 16009-13-5 | MFCD00010726 | 1G
Hemin (from porcine), 16009-13-5, MFCD00010726, 1G
Chem-Impex International, Inc. Bilirubin | 635-65-4 | MFCD00005499 | 1G
Bilirubin, 635-65-4, MFCD00005499, 1G