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2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings
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2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings
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2-Thiouridine is a modified nucleoside provided as a ready-to-use 10 mM solution in DMSO for biochemical and virology research, used to study RNA base-pairing, nonenzymatic replication, and antiviral activity.
Ready-to-use 10 mM solution in DMSO.
Supplied volume 1 mL.
Reported purity 99.7%.
Molecular weight 260.27 g/mol.
CAS number 20235-78-3.
In-solution storage: -80°C (6 months) or -20°C (1 month).
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A heterocyclic building block; has been used in the synthesis of anti-HIV-1 pyrimidinones; has been used as an internal standard for the quantification of thyreostats in bovine plasma
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