Thiophenes
eMolecules 848472-44-6 | tert-Butyl (4-methylthiazol-2-yl)carbamate | ChemScene | MFCD11501911 | 214.280 | C9H14N2O2S | 97.000 | Cc1csc(NC(=O)OC(C)(C)C)n1 | 250mg | 572194787
tert-Butyl (4-methylthiazol-2-yl)carbamate | ChemScene | 848472-44-6 | MFCD11501911 | 214.280 | C9H14N2O2S | 97.000 | Cc1csc(NC(=O)OC(C)(C)C)n1 | 250mg | 572194787
Medchemexpress LLC Acetyl-CoA carboxylase-IN-1 | 179343-23-8 | MFCD12828288 | 99.2% | 395.05 g·mol⁻¹ | C13H9Br2N5 | 10 MG
Acetyl-CoA Carboxylase-IN-1 is a potent small-molecule inhibitor of acetyl-CoA carboxylase used for biochemical and microbiology research. It displays potent ACC inhibition (IC50 ≈ 5 nM) and reported antibacterial activity against Escherichia coli under defined in vitro assay conditions. The material is supplied as a solid (off-white to light yellow) for research use only and should be stored and handled according to the supplier's SDS.
- Potent ACC inhibitor with IC50 ≈ 5 nM.
- Antibacterial activity reported against Escherichia coli in vitro.
- Chemical identifiers: CAS 179343-23-8; formula C13H9Br2N5; MW 395.05 g·mol⁻¹.
- High purity (manufacturer-reported ~99.18%).
- Available in small research pack sizes (e.g., 10 mg) as a solid.
- Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months).
Apexbio Technology LLC GSK-LSD1 2HCl 2102933-95-7 5mg
GSK-LSD1 2HCl (CAS 2102933-95-7) is a selective irreversible inhibitor of lysine-specific demethylase 1A (LSD1) a flavin-dependent histone demethylase that modulates mono- and dimethylated lysine residues and is implicated in processes such as oocyte growth and tissue-specific differentiation GSK-LSD1 2HCl inhibits LSD1 with an IC50 of 16 nM and exhibits over 1000-fold selectivity against related FAD-utilizing enzymes including LSD2 MAO-A and MAO-B In cancer cell lines it demonstrates EC50 values below 5 nM for both gene expression modulation and growth inhibition GSK-LSD1 2HCl serves as a valuable chemical probe in epigenetics and cancer research
eMolecules Synthonix / 3-aminothiophene-2-carboxamide / 5g / 784552335 / AC77867 / / 147123-47-5 / MFCD00052593 / 142.180 / C5H6N2OS
Synthonix / 3-aminothiophene-2-carboxamide / 5g / 784552335 / AC77867 / / 147123-47-5 / MFCD00052593 / 142.180 / C5H6N2OS
eMolecules 6165-68-0 | Thiophene-2-boronic acid | Apollo Scientific | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 25g | 562435432
Thiophene-2-boronic acid | Apollo Scientific | 6165-68-0 | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 25g | 562435432
Medchemexpress LLC Gyki 52466 dihydrochloride | 2319722-40-0 | 99.8% | 366.24 | C17H17Cl2N3O2 | 50 MG
GYKI 52466 dihydrochloride is a selective, noncompetitive antagonist of AMPA and kainate ionotropic glutamate receptors used in preclinical neuroscience research. It is orally active, shows blood-brain barrier permeability, and has demonstrated anticonvulsant and neuroprotective effects in animal studies. Supplied as a solid for laboratory use.
- Selective noncompetitive AMPA and kainate receptor antagonist.
- Orally active with blood-brain barrier permeability.
- Demonstrated anticonvulsant and neuroprotective effects in preclinical studies.
- Supplied as a yellow to orange solid for laboratory use.
- Store sealed, away from moisture and light; in solvent store at -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Ucm-13369 (dihydrochloride) | 99.9% | 462.46 g/mol | C25H33Cl2N3O | 10 MG
UCM-13369 dihydrochloride is a research-grade small-molecule inhibitor of nucleophosmin 1 (NPM1) used for in vitro studies of apoptosis and AML-related pathways. It is supplied as a solid with confirmed high purity and solubility properties for DMSO stock preparation.
- Inhibits NPM1-associated pathways and induces apoptosis in AML models.
- High purity (99.87%) suitable for research applications.
- Available in multiple pack sizes, including 10 mg.
- Soluble in DMSO at 200 mg/mL for stock solution preparation.
- Powder stable at -20°C for long-term storage; solutions require cold storage.
Apexbio Technology LLC Pramipexole 2HCl Monohydrate 191217-81-9 10mM (in 1mL DMSO)
Pramipexole 2HCl Monohydrate is a synthetic non-ergoline dopamine receptor agonist targeting dopamine receptor subtypes particularly D3 D2S D2L and D4 It is designed to activate these receptors thereby modulating dopaminergic transmission pathways Pramipexole 2HCl Monohydrate exerts its biological activity primarily through selective receptor activation Based on these pharmacological properties Pramipexole 2HCl Monohydrate holds research potential in studies of receptor-ligand interactions receptor subtype functional analysis and dopamine-related neurologic or psychiatric disorders including Parkinson s disease and restless legs syndrome
Apexbio Technology LLC GSK-LSD1 2HCl 2102933-95-7 10mM (in 1mL DMSO)
GSK-LSD1 2HCl (CAS 2102933-95-7) is a selective irreversible inhibitor of lysine-specific demethylase 1A (LSD1) a flavin-dependent histone demethylase that modulates mono- and dimethylated lysine residues and is implicated in processes such as oocyte growth and tissue-specific differentiation GSK-LSD1 2HCl inhibits LSD1 with an IC50 of 16 nM and exhibits over 1000-fold selectivity against related FAD-utilizing enzymes including LSD2 MAO-A and MAO-B In cancer cell lines it demonstrates EC50 values below 5 nM for both gene expression modulation and growth inhibition GSK-LSD1 2HCl serves as a valuable chemical probe in epigenetics and cancer research
Medchemexpress LLC Acetyl-CoA Carboxylase-IN-1 | 179343-23-8 | C13H9Br2N5 | 100 MG
Acetyl-CoA Carboxylase-IN-1 is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of less than 5 nM. It also exhibits antibacterial activity. This product is for research use only and not intended for sale to patients.
- Potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of less than 5 nM
- Exhibits antibacterial activity
- Demonstrates antibacterial activity against E. coli with varying MIC values depending on the strain
Medchemexpress LLC Netropsin dihydrochloride | 18133-22-7 | 1 MG
Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder) and antibiotic. It inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. It also possesses antibacterial and antiviral activity.
- Potential antibiotic and antiviral properties by binding to dsDNA in a non-intercalative manner.
- Improves survival from murine endotoxaemia by attenuating NOS2 induction through interference with HMGA1 DNA binding to the core NOS2 promoter.
- Radioprotective ability against radiation-induced damage in solutions of DNA due to high binding affinity and structural stabilization.
