Thiophenes
Medchemexpress LLC Rimcazole dihydrochloride | 75859-03-9 | 100.0% | 394.38 | 25 MG
Rimcazole dihydrochloride is a carbazole derivative that acts in part as a sigma (σ) receptor antagonist. It also binds with moderate affinity to the dopamine transporter and inhibits dopamine uptake. It can reduce locomotor activity and sensitization and can be used for cancer research.
- Acts as a sigma (σ) receptor antagonist
- Binds to the dopamine transporter
- Inhibits dopamine uptake
- Reduces locomotor activity and sensitization
- Can be used for cancer research
Medchemexpress LLC Ro 10-5824 dihydrochloride | 189744-94-3 | 99.9% | 353.29 | C17H22Cl2N4 | 1 ML
Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist supplied for research use. It is offered as a ready-to-use 10 mM solution in DMSO (1 mL) or as a solid, and is characterized for potency, purity, and identity for receptor pharmacology and in vitro studies.
- Selective dopamine D4 receptor partial agonist with reported Ki = 5.2 nM.
- Provided as a 10 mM solution in DMSO (1 mL) or as solid quantities for custom dosing.
- High purity (reported 99.86%), suitable for analytical and biological assays.
- Molecular weight 353.29, chemical formula C17H22Cl2N4, CAS 189744-94-3.
- Characterized with supporting documentation including datasheet, COA, LCMS, and SDS.
- Intended for receptor pharmacology, signaling studies, and in vitro assay applications.
Medchemexpress LLC Zalunfiban dihydrochloride | 2815778-41-5 | 99.1% | 1 MG
Zalunfiban dihydrochloride is a research reagent that acts as a selective platelet glycoprotein IIb/IIIa (αIIbβ3) antagonist, used to study platelet aggregation and myocardial infarction mechanisms. The compound is supplied as the dihydrochloride salt with defined purity, molecular properties, and solubility profiles suitable for in vitro and in vivo research.
- Selective αIIbβ3 antagonist with IC50 ≈ 45 nM.
- High purity (≈99.1%) appropriate for biochemical assays.
- Chemical formula C16H20Cl2N8O2S; molecular weight 459.35 g/mol.
- Soluble in DMSO (10 mg/mL); compatible with common in vivo co-solvent systems.
- Storage guidance: solid at 4°C; store solutions at -80°C for long-term stability.
eMolecules methyl 4-aminothiophene-3-carboxylate hydrochloride | 39978-14-8 | MFCD00068149 | 5g
Pharmablock | methyl 4-aminothiophene-3-carboxylate hydrochloride | 5g | 551094616 | PB93298-1 | | 39978-14-8 | MFCD00068149 | 193.650 | C6H8ClNO2S
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Medchemexpress LLC Lesopitron dihydrochloride | 132449-89-9 | 98.0% | 393.74 g/mol | C15H23Cl3N6 | 5 MG
Lesopitron dihydrochloride is a selective, full agonist of the 5-HT1A receptor used in research to investigate serotonergic signaling and pharmacology. Supplier-reported data indicate activity in rodent tissues (IC50 ≈125 nM) and effects on adenylate cyclase activity and neuronal firing, supporting use in both in vitro and in vivo studies.
- Selective full 5-HT1A receptor agonist.
- Reported IC50 ≈125 nM in rat hippocampal membranes.
- Modulates forskolin-stimulated adenylate cyclase activity.
- Demonstrated activity in vitro and in vivo assays.
- Supplied in small, research-oriented pack sizes for pharmacology studies.
Medchemexpress LLC Way-100135 dihydrochloride | 149055-79-8 | 98.1% | 468.46 g/mol | C24H35Cl2N3O2 | 5 MG
WAY-100135 dihydrochloride is a research-grade small molecule used as a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. Supplied as the dihydrochloride salt with reported in vitro potency (IC50 ≈ 34 nM) and high purity, it is intended for pharmacology and neuroscience studies.
- Selective antagonist of 5-HT1A receptors.
- High purity suitable for analytical and preclinical research.
- Commonly used for receptor pharmacology and signaling studies.
- Available in small pack sizes for laboratory experiments.
- Molecular weight provided for dosing and calculation purposes.
Selleck Chemical LLC Methyl 3-aminopropanoate HCl
-Alanine ethyl ester is the ethyl ester of the non-essential amino acid -alanine
Medchemexpress LLC Lomerizine dihydrochloride | 101477-54-7 | 100.0% | 541.46 | C27H32Cl2F2N2O3 | 10 MG
Lomerizine dihydrochloride is a research chemical that acts as an antagonist of L-type and T-type voltage-gated calcium channels. It is used in preclinical and in vitro studies investigating calcium signaling, migraine mechanisms, and vascular effects.
- Antagonist of L- and T-type voltage-gated calcium channels.
- High reported purity (99.95%).
- Molecular weight 541.46 g/mol.
- CAS number 101477-54-7 for unambiguous identification.
- Supplied as a solid in 10 mg quantities for small-scale research use.
- Intended for research purposes; follow safety and handling guidance.
Medchemexpress LLC Thiophene-2-amidoxim 500mg | 108443-93-2 | 142.18 g/mol | C5H6N2OS | 500 MG
Thiophene-2-amidoxime is a small-molecule synthetic intermediate used in pharmaceutical and medicinal chemistry as a precursor for constructing heterocyclic compounds and for method development in drug synthesis. It is supplied as a solid at research-grade purity for laboratory use.
- High purity suitable for research and synthesis applications.
- Solid form, easy to weigh and handle in standard laboratory procedures.
- Commonly used as a building block in heterocyclic and medicinal chemistry.
- Available in small lab-scale quantities for method development.
- Compatible with common organic solvents and standard synthetic reactions.
Apexbio Technology LLC Vatalanib (PTK787) 2HCl 212141-51-0 50mg
Vatalanib (PTK787) 2HCl (CAS 212141-51-0) is a small molecule inhibitor targeting vascular endothelial growth factor (VEGF) receptor tyrosine kinases including VEGFR/KDR (IC50 0 037 M) VEGFR/Flt-1 (IC50 0 077 M) and VEGFR/Flk (IC50 0 27 M) It also inhibits other receptor tyrosine kinases such as PDGFR- (IC50 0 58 M) c-Kit (IC50 0 73 M) and c-Fms (IC50 1 4 M) Through blockade of these pathways Vatalanib suppresses VEGF-mediated signaling and angiogenesis It is utilized in research investigating mechanisms of angiogenesis and has potential applications in studies of solid tumors and other angiogenesis-dependent diseases
Medchemexpress LLC Gyki 52466 dihydrochloride | 2319722-40-0 | MFCD00153803 | 99.8% | 366.24 g/mol | C17H17Cl2N3O2 | 10 MG
GYKI 52466 dihydrochloride is a selective, noncompetitive antagonist of AMPA and kainate ionotropic glutamate receptors used in pharmacological research into anticonvulsant effects, neuroprotection, and excitatory neurotransmission studies.
- Selective noncompetitive AMPA/kainate receptor antagonist.
- Orally active with documented anticonvulsant activity.
- High purity for research use (≈99.8%).
- Supplied in small-molecule research quantities (e.g., 10 MG).
- Molecular weight 366.24 g/mol; CAS 2319722-40-0.
- Store sealed, away from moisture and light; recommended storage at 4°C (in solvent: -80°C/-20°C for long-term/short-term).
Selleck Chemical LLC Lomerizine 2HCl S4084-1g
Lomerizine dihydrochloride (KB-2796) is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine
![eMolecules Methyl 2-(2-aminobenzo[d]thiazol-6-yl)acetate | 99738-99-5 | MFCD18643368 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502141664.JPG-250.jpg)
eMolecules Methyl 2-(2-aminobenzo[d]thiazol-6-yl)acetate | 99738-99-5 | MFCD18643368 | 1g
Ambeed | Methyl 2-(2-aminobenzo[d]thiazol-6-yl)acetate | 1g | 600845972 | A701819 | | 99738-99-5 | MFCD18643368 | 222.260 | C10H10N2O2S
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Selleck Chemical LLC Quinacrine 2HCl S4255-1g
Quinacrine 2HCl(Quinacrine dihydrochloride) is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent Quinacrine is an effective phospholipase A2 inhibitor
Apexbio Technology LLC PX-478 2HCl 685898-44-6 100mg
PX-478 2HCl (CAS 685898-44-6) commonly known as PX-478 is a small molecule inhibitor targeting hypoxia-inducible factor-1 (HIF-1 ) a transcription factor involved in regulating cellular responses to hypoxic stress including glycolysis angiogenesis and erythropoiesis PX-478 reduces HIF-1 protein levels in multiple tumor cell lines under both normoxic and hypoxic conditions demonstrating IC50 values around 20-30 M depending on cell type In xenograft studies with C6 tumor-bearing mice oral administration of PX-478 inhibited HIF-1 transcriptional activity within tumor hypoxic zones PX-478 is utilized as a research tool to examine hypoxia-related tumor biology and to explore therapeutic sensitization strategies