Carboximidamides
Medchemexpress LLC PXS-5120A | 2125955-70-4 | 98.1% | 50 MG
PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase-like 2/3 (LOXL2/3) with anti-fibrotic activity. It demonstrates high selectivity for LOXL2 over LOXL and effectively inhibits various forms of LOXL2, LOXL3, and LOXL4.
- Potent, irreversible fluoroallylamine inhibitor
- Exhibits anti-fibrotic activity
- Highly selective for LOXL2 (Ki of 83 nM; pIC50 of 8.4) over LOXL (pIC50 of 5.8)
- Inhibits recombinant human, fibroblast, mouse, and rat LOXL2, as well as human LOXL3 and LOXL4
- Readily absorbed following oral gavage in vivo with prolonged plasma concentrations
Sigma Aldrich Fine Chemicals Biosciences Metformin Impurity A | 461-58-5 | MFCD00008066 | 25mg
Metformin Impurity A | Mol Wt: 84.08 | 461-58-5 | MFCD00008066 | 25mg
eMolecules 70-53-1 | H-DL-Lys-OH??HCl | Ambeed | MFCD00064563 | 182.650 | C6H15ClN2O2 | 95.000 | Cl.NCCCCC(N)C(O)=O | 5g | 525052035
H-DL-Lys-OH??HCl | Ambeed | 70-53-1 | MFCD00064563 | 182.650 | C6H15ClN2O2 | 95.000 | Cl.NCCCCC(N)C(O)=O | 5g | 525052035
![eMolecules 771580-70-2 | [4-(TRIFLUOROMETHYL)PYRIDINE-3-YL]METHYLAMINE | AstaTech | MFCD06201889 | 176.142 | C7H7F3N2 | 95.000 | NCc1cnccc1C(F)(F)F | 0.25g | 449739581](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502466483.JPG-250.jpg)
eMolecules 771580-70-2 | [4-(TRIFLUOROMETHYL)PYRIDINE-3-YL]METHYLAMINE | AstaTech | MFCD06201889 | 176.142 | C7H7F3N2 | 95.000 | NCc1cnccc1C(F)(F)F | 0.25g | 449739581
[4-(TRIFLUOROMETHYL)PYRIDINE-3-YL]METHYLAMINE | AstaTech | 771580-70-2 | MFCD06201889 | 176.142 | C7H7F3N2 | 95.000 | NCc1cnccc1C(F)(F)F | 0.25g | 449739581
Selleck Chemical LLC Allantoin S3856-25mg
Allantoin (Glyoxyldiureide 5-Ureidohydantoin) produced from uric acid is a major metabolic intermediate in most organisms including animals plants and bacteria
Chem-Impex International, Inc. Chloro-dipyrrolidinocarbenium hexafluorophosphate | MFCD00191333 | 25G
Chloro-dipyrrolidinocarbenium hexafluorophosphate, MFCD00191333, 25G
Chem-Impex International, Inc. Fluoro-N,N,N',N'-bis(tetramethylene)formamidinium hexafluorophosphate | 164298-25-3 | MFCD02683430 | 5G
Fluoro-N,N,N',N'-bis(tetramethylene)formamidinium hexafluorophosphate, 164298-25-3, MFCD02683430, 5G
Medchemexpress LLC Atx inhibitor 1 | 2225892-70-4 | 99.3% | 501.30 g/mol | C21H23Cl2N2O6P | 5 MG
ATX inhibitor 1 is a potent autotaxin (ATX) inhibitor with nanomolar activity (IC50 = 1.23 nM by FS-3 assay; 2.18 nM by bis-pNPP). It is supplied as a solid research compound for in vitro and preclinical research use only.
- Potent autotaxin inhibitor with nanomolar IC50 values (1.23 nM FS-3; 2.18 nM bis-pNPP).
- Molecular formula: C21H23Cl2N2O6P.
- Molecular weight: 501.30 g/mol.
- Purity: 99.3% by HPLC.
- Physical form: solid powder.
- Storage: powder -20°C for 3 years or 4°C for 2 years; in solvent -80°C for 6 months.
- Available sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, or 10 mM in DMSO solutions.
- For research use only; not for human therapeutic use.
Medchemexpress LLC Nortanshinone | 97399-70-7 | 1 MG
Nortanshinone is a pigment isolated from Dan-Shen, appearing as a brown to reddish-brown solid. It is classified under quinones and naphthalene quinones.
- For laboratory research
- Purity of 98.0%
- Molecular formula: C17H12O4
- Molecular weight: 280.27
- Isolated from plants such as Leguminosae and Labiatae
Selleck Chemical LLC Rhosin hydrochloride 10mM 1mL in DMSOPurity 99.99
Rhosin hydrochloride 10mM 1mL in DMSOPurity 99.99
Sigma Aldrich Fine Chemicals Biosciences Clonidine hydrochloride solid | 4205-91-8 | MFCD00036705 | 250MG
Clonidine hydrochloride solid | Mol Wt: 266.55 | 4205-91-8 | MFCD00036705 | 250MG
Medchemexpress LLC PXS-5120A | 2125955-70-4 | 98.1% | C22H25ClFN3O4S | 10MG
PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of lysyl oxidase-like enzymes LOXL2 and LOXL3, described in the medicinal chemistry literature as a mechanism-based inhibitor with anti-fibrotic activity and high selectivity for LOXL2. It is supplied for research use and has been characterized by CAS, formula, and molecular weight in supplier and public databases.
- Irreversible mechanism-based inhibitor of LOXL2 and LOXL3.
- Greater than 300-fold selectivity for LOXL2 versus LOX.
- Reported Ki ~83 nM for LOXL2 and pIC50 ≈ 8.4.
- Suitable for anti-fibrotic and LOXL biology research.
- Characterized molecular formula and molecular weight for analytical use.
Medchemexpress LLC Allantoin | 97-59-6 | MFCD00005260 | 98.9% | 158.12 g/mol | C4H6N4O3 | 10 MG
Allantoin analytical standard supplied for research and analytical applications, including method development, calibration, and quality control. It is a crystalline compound with a molecular weight of 158.12 g/mol and reported high purity suitable for laboratory reference use.
- High-purity analytical standard for assay calibration
- Suitable for method development and quality control
- Available in small reference quantities for laboratory use
- Chemical formula C4H6N4O3; molecular weight 158.12 g/mol
- Storage and handling details provided in the certificate of analysis