Isocyanates
Medchemexpress LLC Der p 23 protein, Dermatophagoides pteronyssinus | >95.0% | 100 UG
Der p 23 is a recombinant major allergen from the house dust mite Dermatophagoides pteronyssinus, expressed in HEK293 cells and supplied as a lyophilized C-terminal His-tagged protein. It is >95% pure by reducing SDS-PAGE, has an approximate molecular weight of 19 kDa, and endotoxin <1 EU/μg. The product is formulated in PBS (pH 7.4) and is recommended to be stored at -20°C; add carrier protein for long-term storage.
- Recombinant protein expressed in HEK293 cells.
- C-terminal His tag for purification and detection.
- High purity (>95%) suitable for immunological assays.
- Low endotoxin level (<1 EU/μg) for sensitive applications.
- Lyophilized formulation; PBS-based, recommended -20°C storage.
Medchemexpress LLC Hexamethylene bisacetamide | 3073-59-4 | MFCD00008684 | 99.6% | 200.28 | C10H20N2O2 | 100MG
Hexamethylene bisacetamide (HMBA) is a small-molecule differentiation inducer used in cell biology and cancer research to promote terminal differentiation and modulate signaling pathways. It is provided as a high-purity solid suitable for in vitro experiments and biochemical studies, with specified solubility and storage conditions for short- and long-term use.
- High purity (99.6%).
- Molecular weight 200.28.
- Chemical formula C10H20N2O2.
- Soluble in water (100 mg/mL) and DMSO (25 mg/mL) with ultrasonic assistance.
- Appearance: white to off-white solid, supplied in 100 mg packaging.
- Storage: long-term 4°C protected from light; in solution -80°C for 6 months or -20°C for 1 month.
Cayman Chemical Zeaxanthin Fatty Acids and Der
A carotenoid with diverse biological activities; decreases immobility time in the forced swim test and reduces hippocampal levels of IL-6, IL-1β, and TNF-α in a rat model of STZ-induced diabetes at 50 mg/kg; reduces albuminuria, serum levels of urea nitrogen and MDA, and kidney damage in a rat model of STZ-induced diabetic nephropathy; high dietary intake of zeaxanthin is positively correlated with reduced risk of advanced neovascular age-related macular degeneration in humans
Cayman Chemical 14 15EpETE Fatty Acids and Der
EDHF is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (NO) and COX-derived (prostacyclin) vasodilators.{6485,7204} CYP450 metabolism of PUFAs, produces epoxides such as (±)14(15)-EpETrE which are prime candidates for the actual active mediator.{5826} However, the CYP450 metabolites of EPA (Item No. 90110) and DHA (Item No. 90310) have been little studied relative to arachidonate epoxygenase metabolites. (±)14(15)-EpETE is the ω-3 homolog of (±)14(15)-EpETrE, derived via epoxidation of the 14,15-double bond of EPA. The EDHF activity of (±)14(15)-EpETE has not yet been determined.
Cayman Chemical 14 15EpEDE Fatty Acids and Der
An EpEDE acid formed from DGLA, either by a strong oxidizing agent or by cytochrome P450 epoxygenases; biological properties are poorly understood
Medchemexpress LLC Der p 23 protein | >95.0% | 10 UG
Recombinant Der p 23 protein (residues A22-T90) is a C-terminal His-tagged, HEK293-expressed allergen supplied as a lyophilized powder for immunological assays, antibody generation, and allergy research.
- Recombinant major mite allergen suitable for allergy research.
- Expressed in HEK293 for eukaryotic post-translational modifications.
- C-terminal His tag enables affinity purification and detection.
- High purity (>95.0%) confirmed by reducing SDS-PAGE.
- Low endotoxin (<1 EU/μg) suitable for sensitive immunoassays.
- Lyophilized format for long-term storage and convenient handling.
- Includes storage and reconstitution guidance to preserve activity.
Cayman Chemical LBiopterin Fatty Acids and Der
An intermediate for tetrahydro-L-biopterin; oxidized form of BH4, a NOS cofactor; toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs); rarely found under physiological conditions except in the epidermis of patients with Vitiligo
Cayman Chemical Quinestrol Fatty Acids and Der
A synthetic estrogen; effective in hormone replacement therapy
Cayman Chemical Perifosine Fatty Acids and Der
An alkylphospholipid that induces apoptotic cell death in a time- and dose-dependent manner in a variety of tumor cell lines but not in normal vascular endothelial cells; causes inhibition of PC-3 prostate carcinoma cell growth (GI50 = 5 µM at 24h) associated with rapidly decreased Akt activation; induces p21WAF1 expression in squamous carcinoma cells, leading to loss in cyclin-dependent kinase activity and cell cycle arrest
eMolecules P-Tolyl isocyanate | 374675-64-6 | 1G | Purity: 95%
Combi-Blocks | P-Tolyl isocyanate | 1G | 374675-64-6 | MFCD00002029
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Medchemexpress LLC 2-Amino-5-methylbenzoic acid | 2941-78-8 | 151.16 | 500 G
2-Amino-5-methylbenzoic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is an impurity of cetilistat.
- Biochemical reagent
- Biological material or organic compound
- Used for life science related research
- Off-white to light yellow solid appearance
- Purity of 99.8%
- Molecular weight of 151.16
- Store powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC FG-3019 10mg | 10mg
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF) FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2]
Medchemexpress LLC Der p 23 protein (Dermatophagoides pteronyssinus) | >95.0% | 5 UG
Recombinant Der p 23 is the mature major allergen from the house dust mite Dermatophagoides pteronyssinus, provided lyophilized for laboratory use. The preparation corresponds to amino acids A22-T90, is expressed in HEK293 cells with a C-terminal His tag, and is supplied at 5 μg with >95% purity. It is intended for immunoassays, antibody production, and allergen characterization.
- Expressed in HEK293 cells for eukaryotic folding and modifications.
- C-terminal His tag facilitates detection and purification.
- Purity >95.0% as determined by reducing SDS-PAGE.
- Contains the mature region A22-T90, approx. 19 kDa.
- Lyophilized from PBS, pH 7.4, for increased stability.
- Supplied as 5 μg aliquots suitable for analytical assays.
- Store lyophilized at -20°C; aliquot and freeze for long-term storage.
- Suitable for immunoassays and antibody generation applications.
Medchemexpress LLC 5-(N,N-Hexamethylene)-amiloride | 1428-95-1 | 99.1% | 1 ML
5-(N,N-Hexamethylene)-amiloride, also known as Hexamethylene amiloride (HMA), is a potent Na+/H+ exchanger inhibitor derived from amiloride. It effectively decreases intracellular pH (pHi) and has been shown to induce apoptosis in leukemic cells. This compound also acts as an inhibitor of the HIV-1 Vpu virus ion channel and inhibits the replication of mouse hepatitis virus (MHV) and human coronavirus 229E (HCoV229E) in cultured L929 cells.
- Potent Na+/H+ exchanger inhibitor
- Decreases intracellular pH (pHi)
- Induces apoptosis in leukemic cells
- Inhibits HIV-1 Vpu virus ion channel
- Inhibits replication of mouse hepatitis virus (MHV) and human coronavirus 229E (HCoV229E)
- Inhibits human cardiac ion channels hERG, Nav1.5, and Cav1.2
- Exhibits microsomal and mouse plasma stability
- Displays Caco-2 cell permeability
Cayman Chemical 11 12EpETE Fatty Acids and Der
An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo; its effects of remain to be determined