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Nitrogen mustard compounds

Nitrogen mustards are cytotoxic organic compounds with the chloroethylamine functional group, which consists of the following structure: Cl(CH2)2NR2, where R can be any organic group. They are nitrogen analogs of mustard gas.
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Keyword Search:
136 – 150 of 188 results
136

Medchemexpress LLC 1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4 | 56239-24-8 | 99.0% | C9H12D4ClN3O3 | 1 MG
SDP

trans-4'-Hydroxy CCNU Lomustine-d4 is a deuterium-labeled compound, primarily used as a tracer or as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes, like deuterium, into drug molecules serves as a critical method for quantitation during drug development, with the potential to influence pharmacokinetic and metabolic profiles.

  • Can be used as a tracer.
  • Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
  • Deuterium labeling can affect pharmacokinetic and metabolic profiles of drugs.

ENCOMPASS_PREFERRED
137

Medchemexpress LLC Toringin | 1329-10-8 | 5 MG
SDP

Toringin is a bioflavonoid isolated from the bark of Docyniopsis tschonoski. It decreases the cis-effect of expanded CTG repeats and cytotoxicity, and rescues PC12 neuronal cells when exposed to isosakuranetin. As a flavonoid, Toringin exhibits various biological activities beneficial against conditions such as cancers and coronary heart disease, and is effective in ameliorating RNA gain of function caused by expanded CTG repeats.

  • Decreases cis-effect of expanded CTG repeats
  • Decreases cytotoxicity
  • Rescues PC12 neuronal cells
  • Ameliorates RNA gain of function
  • Exhibits various biological activities
  • Beneficial against cancers and coronary heart disease

ENCOMPASS_PREFERRED
138

eMolecules​ 50893-53-3 | 1-Chloroethyl chloroformate | Oakwood Chemical | MFCD00000647 | 142.960 | C3H4Cl2O2 | 99.000 | CC(Cl)OC(Cl)=O | 1kg | 537678299

1-Chloroethyl chloroformate | Oakwood Chemical | 50893-53-3 | MFCD00000647 | 142.960 | C3H4Cl2O2 | 99.000 | CC(Cl)OC(Cl)=O | 1kg | 537678299

ENCOMPASS_PREFERRED
139

Chemscene (4-Aminobutyl)dimethylamine 25g

(4-Aminobutyl)dimethylamine 25g

ENCOMPASS_PREFERRED
140

eMolecules​ 407-24-9 | Bistrifluoroacetamide | Combi-Blocks, Inc. | MFCD00013564 | 209.047 | C4HF6NO2 | 98.000 | FC(F)(F)C(=O)NC(=O)C(F)(F)F | 25g | 586077145

Bistrifluoroacetamide | Combi-Blocks, Inc. | 407-24-9 | MFCD00013564 | 209.047 | C4HF6NO2 | 98.000 | FC(F)(F)C(=O)NC(=O)C(F)(F)F | 25g | 586077145

ENCOMPASS_PREFERRED
141

Medchemexpress LLC 5-amino-N-(3-fluoro-4-methoxybenzyl)-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide | 1451994-10-7 | 99.3% | 50 MG
SDP

VU0467485 (AZ13713945) is a potent, selective, orally bioavailable positive allosteric modulator of the muscarinic acetylcholine receptor M4, provided as a research reagent for receptor pharmacology and preclinical studies.

  • Potent and selective M4 positive allosteric modulator.
  • Orally bioavailable properties support in vivo evaluation.
  • High purity suitable for pharmacological assays.
  • Available in multiple pack sizes, including 50 mg.
  • Commonly used for studies of M4 signaling and antipsychotic-like activity in preclinical models.

ENCOMPASS_PREFERRED
142

Medchemexpress LLC Mizagliflozin | 666843-10-3 | 99.2% | 564.67 | 5 MG
SDP

Mizagliflozin (DSP-3235 free base) is a potent, orally active, and selective SGLT1 inhibitor with a Ki of 27 nM for human SGLT1. It shows 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. It also exhibits potential in the amelioration of chronic constipation.

  • Potent, orally active, and selective SGLT1 inhibitor (Ki of 27 nM for human SGLT1)
  • 303-fold selectivity over SGLT2
  • Solid appearance, off-white to light yellow color
  • Used as an antidiabetic agent to modify postprandial blood glucose excursion
  • Exhibits potential in the amelioration of chronic constipation

ENCOMPASS_PREFERRED
143

Medchemexpress LLC ML-184 10mg | 794572-10-4 | 470.63 g·mol⁻¹ | C25H34N4O3S | 10 MG
SDP

ML-184 is a selective GPR55 agonist research compound supplied for in vitro and preclinical pharmacology studies. It is provided as a solid and as ready-to-use DMSO solutions, and is characterized by molecular formula C25H34N4O3S and molecular weight 470.63 g·mol⁻¹.

  • Selective GPR55 agonist (EC50 ≈ 250 nM)
  • Suitable for in vitro and preclinical research applications
  • Available as a 10 mg solid and as 10 mM solution in DMSO
  • High purity (99.57%) as provided by manufacturer
  • Store powder at -20°C for long-term stability; store solutions at -80°C for extended storage

ENCOMPASS_PREFERRED
144

Medchemexpress LLC Cdc25b-in-1 | 2374831-10-2 | 98.1% | 321.37 g/mol | C20H19NO3 | 10MG
SDP

CDC25B-IN-1 is a small-molecule research inhibitor of the cell division cycle 25B (CDC25B) phosphatase, referred to in the literature as compound 4a. It is provided as a 10 mg research sample (CAS 2374831-10-2) for biochemical and cellular studies targeting CDC25B-mediated signaling.

  • Potent CDC25B inhibition with reported Ki of 8.5 μM.
  • High purity suitable for research (≈98.1%).
  • Molecular weight 321.37 g/mol; formula C20H19NO3.
  • Suitable for in vitro biochemical and cell-based assays.
  • Storage under nitrogen recommended; refrigerated at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
  • Supplied as a small quantity research sample for laboratory use.

ENCOMPASS_PREFERRED
145

eMolecules​ 1122-54-9 | 4-Acetylpyridine | Ambeed | MFCD00006433 | 121.139 | C7H7NO | 98.000 | CC(=O)c1ccncc1 | 10g | 490549457

4-Acetylpyridine | Ambeed | 1122-54-9 | MFCD00006433 | 121.139 | C7H7NO | 98.000 | CC(=O)c1ccncc1 | 10g | 490549457

ENCOMPASS_PREFERRED
146

Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | C20H21FN2O2 | 100 MG
SDP

HN37 is a potent and chemically stable antiepileptic agent candidate, demonstrating an EC50 of 37 nM for KCNQ2. It functions as a click chemistry reagent, containing an Alkyne group that enables it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. It is also recognized as a potent neuronal Kv7 activator, exhibiting subtype selectivity similar to RTG.

  • Potent and chemically stable antiepileptic agent candidate
  • Functions as a click chemistry reagent
  • Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
  • Potent neuronal Kv7 activator
  • Exhibits subtype selectivity similar to RTG
  • Molecular weight of 340.39
  • Appears as an off-white to light yellow solid
  • Intended for research use only

ENCOMPASS_PREFERRED
147

STA Pharmaceutical 3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid | 5 g | CAS 875211-10-2 | InChIKey RXRDRSUDCSEVRK-UHFFFAOYSA-N

3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.

Specifications
- CAS: 875211-10-2
- MDL: No data
- InChIKey: RXRDRSUDCSEVRK-UHFFFAOYSA-N
- Molecular Weight: 417.505
- Molecular Formula: C26H27NO4
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)adamantane-1-carboxylic acid
- SMILES: OC(C12CC3CC(C2)CC(C1)(NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)C3)=O

ENCOMPASS
148

STA Pharmaceutical 3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid | 10 g | CAS 875211-10-2 | InChIKey RXRDRSUDCSEVRK-UHFFFAOYSA-N

3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.

Specifications
- CAS: 875211-10-2
- MDL: No data
- InChIKey: RXRDRSUDCSEVRK-UHFFFAOYSA-N
- Molecular Weight: 417.505
- Molecular Formula: C26H27NO4
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)adamantane-1-carboxylic acid
- SMILES: OC(C12CC3CC(C2)CC(C1)(NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)C3)=O

ENCOMPASS
149

Medchemexpress LLC ZL0580 | 2377151-10-3 | 99.4% | 532.53 | C25H23F3N4O4S | 5 MG
SDP

ZL0580 is a BRD4 BD1-binding small molecule that induces epigenetic suppression of HIV by inhibiting Tat transactivation and transcription elongation and by promoting a repressive chromatin structure at the HIV promoter. It is supplied as a high-purity solid or as DMSO solutions for research applications and is stable under recommended storage conditions.

ENCOMPASS_PREFERRED
150

eMolecules​ 471254-10-1 | 3-PYRROLIDINECARBOXAMIDE | AstaTech | MFCD09037932 | 114.148 | C5H10N2O | 95.000 | NC(=O)C1CCNC1 | 0.1g | 718055558

3-PYRROLIDINECARBOXAMIDE | AstaTech | 471254-10-1 | MFCD09037932 | 114.148 | C5H10N2O | 95.000 | NC(=O)C1CCNC1 | 0.1g | 718055558

ENCOMPASS_PREFERRED