Nitrogen mustard compounds
Medchemexpress LLC RV01 | 1016897-10-1 | 98.1% | 263.29 g/mol | C17H13NO2 | 10MG
RV01 is a resveratrol analogue used as a research tool to probe ALDH2-related pathways and oxidative stress. It inhibits DNA damage, reduces ethanol-induced ALDH2 mRNA expression, scavenges hydroxyl radicals, and decreases iNOS expression, indicating anti-neuroinflammatory activity. Supplied as a powder for biochemical and cell-based research applications.
- Inhibits DNA damage and reduces ALDH2 mRNA expression.
- Scavenges hydroxyl radicals, indicating antioxidant activity.
- Decreases iNOS expression and exhibits anti-neuroinflammatory effects.
- Provided as a research-grade powder suitable for biochemical studies.
- High purity for reliable experimental results.
Medchemexpress LLC ZL0580 | 2377151-10-3 | 99.4% | 532.53 | C25H23F3N4O4S | 5 MG
ZL0580 is a BRD4 BD1-binding small molecule that induces epigenetic suppression of HIV by inhibiting Tat transactivation and transcription elongation and by promoting a repressive chromatin structure at the HIV promoter. It is supplied as a high-purity solid or as DMSO solutions for research applications and is stable under recommended storage conditions.
Medchemexpress LLC Rv01 | 1016897-10-1 | 98.1% | 263.29 g/mol | C17H13NO2 | 50MG
RV01 is a resveratrol analogue that inhibits aldehyde dehydrogenase (ALDH) activity and reduces ethanol-induced ALDH2 mRNA expression. Supplied as a solid research compound for in vitro biochemical and cellular studies, it has documented solubility in DMSO and defined storage/stability conditions.
Medchemexpress LLC CDC25B-IN-1 | 2374831-10-2 | 98.1% | 321.37 g/mol | C20H19NO3 | 50MG
CDC25B-IN-1 is a small-molecule research inhibitor of the cell division cycle 25B (CDC25B) phosphatase. It has a reported Ki of approximately 8.5 μM, reduces cell proliferation and colony formation, and increases the proportion of cells in the G2/M phase. The compound is supplied at high reported purity and is available in multiple pack sizes, including mg quantities and as a DMSO solution suitable for biochemical and cell-based assays.
- Potent inhibitor of CDC25B phosphatase with reported Ki ≈ 8.5 μM.
- Inhibits cell proliferation and colony formation in cellular assays.
- Causes accumulation of cells in the G2/M phase.
- Supplied with high reported purity for research use.
- Available in multiple pack sizes and as a DMSO solution for convenience.
eMolecules 1246998-10-6 | 2-(Pentafluorosulfur)aniline | J&W PharmLab LLC | MFCD21362226 | 219.170 | C6H6F5NS | 96.000 | Nc1ccccc1S(F)(F)(F)(F)F | 50mg | 722712393
2-(Pentafluorosulfur)aniline | J&W PharmLab LLC | 1246998-10-6 | MFCD21362226 | 219.170 | C6H6F5NS | 96.000 | Nc1ccccc1S(F)(F)(F)(F)F | 50mg | 722712393
eMolecules 34981-10-7 | PYRIDINE-2,3,5,6-TETRAAMINE 3HCL | AstaTech | MFCD00235198 | 248.540 | C5H12Cl3N5 | 97.000 | Cl.Cl.Cl.Nc1cc(N)c(N)nc1N | 0.1g | 722706699
PYRIDINE-2,3,5,6-TETRAAMINE 3HCL | AstaTech | 34981-10-7 | MFCD00235198 | 248.540 | C5H12Cl3N5 | 97.000 | Cl.Cl.Cl.Nc1cc(N)c(N)nc1N | 0.1g | 722706699
![Medchemexpress LLC 4-(5-fluoro-1H-benzo[d]imidazol-2-yl)-N,N-dimethylaniline | 1458664-10-2 | MFCD20720876 | 99.6% | 255.29 | C15H14FN3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000222052.png-250.jpg)
Medchemexpress LLC 4-(5-fluoro-1H-benzo[d]imidazol-2-yl)-N,N-dimethylaniline | 1458664-10-2 | MFCD20720876 | 99.6% | 255.29 | C15H14FN3 | 5 MG
β-catenin-IN-2 (Compound H1B1) is a small-molecule β-catenin inhibitor for research use, reported as a pink to red solid with high purity. It is characterized by molecular formula C15H14FN3 and a molecular weight of 255.29 g/mol, and is used in studies of colorectal cancer and β-catenin pathway biology.
- Potent β-catenin inhibitor for colorectal cancer research.
- Molecular formula C15H14FN3.
- Molecular weight 255.29 g/mol.
- Appearance: pink to red solid.
- Purity around 99.6% by HPLC.
- Available in small milligram-scale packages for laboratory studies.
- Typically prepared and handled in solution (DMSO) for assays.
Medchemexpress LLC Swertisin | 6991-10-2 | 1 MG
Swertisin is an oral adenosine A1 receptor antagonist and an SGLT2 inhibitor. It possesses anti-diabetic and antioxidant properties, inhibits HBV, and improves cognitive and memory impairments.
- Acts as an oral adenosine A1 receptor antagonist
- Functions as an SGLT2 inhibitor
- Possesses anti-diabetic properties
- Exhibits antioxidant properties
- Inhibits HBV
- Improves cognitive and memory impairments
eMolecules 1122-96-9 | AstaTech | 4-METHOXYPYRIDINE 1-OXIDE | 5g | 233625492 | 34702 | 95 | MFCD00006207 | 125.127 | C6H7NO2
Medchem Express | Delta-Tocopherol | 50mg | 482204049 | HY-113026 | 119-13-1 | MFCD20486794 | 402.663 | C27H46O2
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eMolecules 1176306-10-7 | Medchem Express | Alamandine | 5mg | 599151279 | HY-P3108 | 855.011 | C40H62N12O9
Ambeed | tert-Butyl 3-iodo-1H-pyrazole-1-carboxylate | 1g | 572931523 | A223374 | 1233513-13-7 | MFCD12407121 | 294.092 | C8H11IN2O2
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Medchemexpress LLC Mizagliflozin | 666843-10-3 | 99.2% | 564.67 | 5 MG
Mizagliflozin (DSP-3235 free base) is a potent, orally active, and selective SGLT1 inhibitor with a Ki of 27 nM for human SGLT1. It shows 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. It also exhibits potential in the amelioration of chronic constipation.
- Potent, orally active, and selective SGLT1 inhibitor (Ki of 27 nM for human SGLT1)
- 303-fold selectivity over SGLT2
- Solid appearance, off-white to light yellow color
- Used as an antidiabetic agent to modify postprandial blood glucose excursion
- Exhibits potential in the amelioration of chronic constipation
Medchemexpress LLC MS4077 | 2230077-10-6 | 99.7% | 1134.73 | 10 MG
MS4077 is an anaplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 37 nM for binding affinity to ALK. It is for research use only and not sold to patients.
- Effectively inhibits cancer cell proliferation.
- Concentration-dependently inhibits proliferation of SU-DHL-1 cells with an IC50 of 46 ± 4 nM.
- Potently reduces ALK fusion protein levels and inhibits ALK auto-phosphorylation and downstream STAT3 phosphorylation in SU-DHL-1 and NCI-H2228 cells.
- Reduces NPM-ALK protein levels with a DC50 of 3 ± 1 nM in SU-DHL-1 cells after 16-hour treatment.
- Achieves over 90% inhibition of both ALK Y1507 and STAT3 Y705 phosphorylation at 100 nM concentration.
- Reduces EML4-ALK protein levels with a DC50 of 34 ± 9 nM in NCI-H2228 cells after 16-hour treatment, with over 90% reduction at 100 nM.
eMolecules 1523618-10-1 | ChemScene | 4-(Cyclopropylsulfonimidoyl)aniline | 100mg | 761283903 | CS-0184344 | MFCD27987215 | 196.27 | C9H12N2OS
Medchem Express | -Lactamase-IN-2 | 5mg | 582658792 | HY-138247 | 2114651-20-4 | 208.188 | C11H9FO3
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eMolecules 19685-10-0 | Medchem Express | 10-Methoxycamptothecin | 5mg | 532150217 | HY-N0446 | MFCD11975376 | 378.384 | C21H18N2O5
Ambeed | (2S5S)-Hexane-25-diol | 250mg | 562292693 | A447376 | 34338-96-0 | MFCD00082583 | 118.176 | C6H14O2
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