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Nitrogen mustard compounds

Nitrogen mustards are cytotoxic organic compounds with the chloroethylamine functional group, which consists of the following structure: Cl(CH2)2NR2, where R can be any organic group. They are nitrogen analogs of mustard gas.
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Keyword Search:
121 – 135 of 175 results
121

Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | 340.39 g/mol | C20H21FN2O2 | 5 MG
SDP

HN37 is a small-molecule research compound that functions as a potent activator of the KCNQ2 potassium channel. It contains an alkyne moiety suitable for click-chemistry derivatization and is intended for in vitro pharmacology and chemical biology applications.

  • Potent KCNQ2 activation with EC50 of 37 nM.
  • Alkyne functional group suitable for copper-catalyzed azide-alkyne cycloaddition.
  • High reported purity for reproducible assay performance.
  • Soluble in DMSO at 50 mg/mL for preparation of concentrated stocks.
  • Available in multiple milligram quantities for research use.

ENCOMPASS_PREFERRED
122

Medchemexpress LLC Rv01 | 1016897-10-1 | 98.1% | 263.29 g/mol | C17H13NO2 | 50MG
SDP

RV01 is a resveratrol analogue that inhibits aldehyde dehydrogenase (ALDH) activity and reduces ethanol-induced ALDH2 mRNA expression. Supplied as a solid research compound for in vitro biochemical and cellular studies, it has documented solubility in DMSO and defined storage/stability conditions.

ENCOMPASS_PREFERRED
123

Medchemexpress LLC Swertisin | 6991-10-2 | 5 MG
SDP

Swertisin is an oral adenosine A1 receptor antagonist and an SGLT2 inhibitor. It exhibits anti-diabetic and antioxidant properties, inhibits HBV, and improves cognitive and memory impairments in mice.

  • Acts as an oral adenosine A1 receptor antagonist and SGLT2 inhibitor
  • Exhibits anti-diabetic and antioxidant properties
  • Inhibits HBV
  • Improves cognitive and memory impairments
  • Inhibits glucose uptake in HEK293 cells
  • Suppresses HBsAg, HBeAg, and HBV DNA levels
  • Reduces SGLT2 expression and lowers blood sugar in vivo

ENCOMPASS_PREFERRED
124

eMolecules​ 1176306-10-7 | Medchem Express | Alamandine | 5mg | 599151279 | HY-P3108 | 855.011 | C40H62N12O9

Ambeed | tert-Butyl 3-iodo-1H-pyrazole-1-carboxylate | 1g | 572931523 | A223374 | 1233513-13-7 | MFCD12407121 | 294.092 | C8H11IN2O2

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eMolecules Building Block Tool

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125

Medchemexpress LLC HN37 | 1821222-10-9 | 99.5% | C20H21FN2O2 | 50 MG
SDP

HN37 is a potent and chemically stable antiepileptic agent candidate with an EC50 of 37 nM for KCNQ2. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In vitro, HN37 is a potent neuronal Kv7 activator with subtype selectivity similar to RTG.

  • Potent and chemically stable antiepileptic agent candidate
  • EC50 of 37 nM for KCNQ2
  • Click chemistry reagent with an Alkyne group
  • Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
  • Potent neuronal Kv7 activator with subtype selectivity similar to RTG

ENCOMPASS_PREFERRED
126

Medchemexpress LLC CDC25B-IN-1 | 2374831-10-2 | 98.1% | 321.37 g/mol | C20H19NO3 | 50MG
SDP

CDC25B-IN-1 is a small-molecule research inhibitor of the cell division cycle 25B (CDC25B) phosphatase. It has a reported Ki of approximately 8.5 μM, reduces cell proliferation and colony formation, and increases the proportion of cells in the G2/M phase. The compound is supplied at high reported purity and is available in multiple pack sizes, including mg quantities and as a DMSO solution suitable for biochemical and cell-based assays.

  • Potent inhibitor of CDC25B phosphatase with reported Ki ≈ 8.5 μM.
  • Inhibits cell proliferation and colony formation in cellular assays.
  • Causes accumulation of cells in the G2/M phase.
  • Supplied with high reported purity for research use.
  • Available in multiple pack sizes and as a DMSO solution for convenience.

ENCOMPASS_PREFERRED
127

Medchemexpress LLC 2-chloroethyl (2-chloroethyl)phosphonate | 17378-30-2 | MFCD24393365 | >95.0% | 206.99 | C4H9Cl2O3P | 5 MG
SDP

2-Chloroethyl (2-chloroethyl)phosphonate is an organophosphorus compound used as an intermediate in organic synthesis. It is a low-molecular-weight phosphonate (C4H9Cl2O3P, MW 206.99) with CAS 17378-30-2, provided with supporting documentation; consult the certificate of analysis for recommended storage and handling.

  • Organophosphorus intermediate for organic synthesis.
  • Molecular formula C4H9Cl2O3P; molecular weight 206.99.
  • CAS number 17378-30-2 for unambiguous identification.
  • Purity greater than 95% by HPLC.
  • Available in small research quantities, such as 5 mg.
  • Supplied with certificate of analysis for storage and handling guidance.

ENCOMPASS_PREFERRED
128

Medchemexpress LLC Vu0467485 | 1451994-10-7 | 99.3% | 25 MG
SDP

VU0467485 (AZ13713945) is a potent, selective, orally bioavailable muscarinic acetylcholine receptor 4 (M4) positive allosteric modulator supplied for research use.

  • Potent and selective M4 positive allosteric modulator
  • Orally bioavailable in preclinical studies
  • High purity suitable for analytical and screening applications
  • Available in small milligram-scale packages for research
  • Characterized molecular weight and formula for reproducibility

ENCOMPASS_PREFERRED
129

Medchemexpress LLC ML-184 10mg | 794572-10-4 | 470.63 g·mol⁻¹ | C25H34N4O3S | 10 MG
SDP

ML-184 is a selective GPR55 agonist research compound supplied for in vitro and preclinical pharmacology studies. It is provided as a solid and as ready-to-use DMSO solutions, and is characterized by molecular formula C25H34N4O3S and molecular weight 470.63 g·mol⁻¹.

  • Selective GPR55 agonist (EC50 ≈ 250 nM)
  • Suitable for in vitro and preclinical research applications
  • Available as a 10 mg solid and as 10 mM solution in DMSO
  • High purity (99.57%) as provided by manufacturer
  • Store powder at -20°C for long-term stability; store solutions at -80°C for extended storage

ENCOMPASS_PREFERRED
130

eMolecules​ 1246998-10-6 | 2-(Pentafluorosulfur)aniline | J&W PharmLab LLC | MFCD21362226 | 219.170 | C6H6F5NS | 96.000 | Nc1ccccc1S(F)(F)(F)(F)F | 50mg | 722712393

2-(Pentafluorosulfur)aniline | J&W PharmLab LLC | 1246998-10-6 | MFCD21362226 | 219.170 | C6H6F5NS | 96.000 | Nc1ccccc1S(F)(F)(F)(F)F | 50mg | 722712393

ENCOMPASS_PREFERRED
131

eMolecules​ 1523618-10-1 | ChemScene | 4-(Cyclopropylsulfonimidoyl)aniline | 100mg | 761283903 | CS-0184344 | MFCD27987215 | 196.27 | C9H12N2OS

Medchem Express | -Lactamase-IN-2 | 5mg | 582658792 | HY-138247 | 2114651-20-4 | 208.188 | C11H9FO3

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eMolecules Building Block Tool<|a>

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132

Medchemexpress LLC 1-(2-chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4 | 00-00-0 | 99.0% | 253.72 | C9H12D4ClN3O3 | 5 MG
SDP

Deuterium-labeled trans-4'-Hydroxy CCNU Lomustine-d4 is a research-grade labeled analogue of trans-4'-Hydroxy lomustine intended for use as a tracer and internal standard in quantitative analytical methods. The product is supplied as a high-purity solid in a 5 MG vial and requires cold storage to maintain stability.

  • Deuterium-labeled internal standard for NMR, GC-MS, and LC-MS.
  • High purity (99.0%).
  • Solid, white to off-white appearance.
  • Suitable as a tracer for pharmacokinetic and metabolic studies.
  • Powder storage: -20°C for long-term stability; in solvent: -80°C for short-term stability.
  • Supplied as a 5 MG vial for laboratory use.

ENCOMPASS_PREFERRED
133

Medchemexpress LLC Bis(2-chloroethyl)amine hydrochloride | 821-48-7 | MFCD00012515 | 98.0% | 178.49 | C4H10Cl3N | 1kg
SDP

Bis(2-chloroethyl)amine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research

ENCOMPASS_PREFERRED
134

Chemscene ChemScene | 4,7-Dibromoisoquinoline | 250MG | CS-0139734 | 0.97 | 223671-10-1| MFCD13191776 | 286.95
SDP

ChemScene | 4,7-Dibromoisoquinoline | 250MG | CS-0139734 | 0.97 | 223671-10-1| MFCD13191776 | 286.95

ENCOMPASS_PREFERRED
135

Medchemexpress LLC 5-amino-N-[(3-fluoro-4-methoxyphenyl)methyl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide | 1451994-10-7 | 99.3% | 5 MG
SDP

VU0467485 is a potent, selective, and orally bioavailable positive allosteric modulator of the muscarinic acetylcholine receptor M4, supplied as a solid research compound for in vitro and in vivo pharmacology studies.

  • Potent M4 positive allosteric modulator.
  • High purity (99.29%).
  • Molecular formula C17H17FN4O2S and molecular weight 360.41 g·mol⁻1.
  • Light yellow to yellow solid appearance.
  • Available in small solid quantities for research, including 5 MG packaging.

ENCOMPASS_PREFERRED