Tertiary amines
eMolecules N-Cyclohexylformamide | 766-93-8 | MFCD00003828 | 25g
Oakwood Chemicals | N-Cyclohexylformamide | 25g | 480150763 | 099604 | | 766-93-8 | MFCD00003828 | 127.187 | C7H13NO
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Medchemexpress LLC Trimethylamine N-oxide dihydrate | 62637-93-8 | 99.9% | 111.14 | 10 MG
Trimethylamine N-oxide dihydrate | 62637-93-8 | 99.9% | 111.14 | 10 MG
Medchemexpress LLC Trimethylamine n-oxide dihydrate | 62637-93-8 | 98.0% | 111.14 | 50 MG
Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite derived from dietary choline and other trimethylamine-containing nutrients. It is known to induce inflammation by activating the ROS/NLRP3 inflammasome. Additionally, this compound accelerates fibroblast-myofibroblast differentiation and promotes cardiac fibrosis through the activation of the TGF-β/smad2 signaling pathway. It is intended for research use only and not for patient use.
- Gut microbe-dependent metabolite
- Induces inflammation via ROS/NLRP3 inflammasome activation
- Accelerates fibroblast-myofibroblast differentiation
- Induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway
- Found in marine organisms, offering protection against adverse environmental effects (temperature, salinity, high urea, hydrostatic pressure)
Medchemexpress LLC Trimethylamine N-oxide dihydrate | 62637-93-8 | ≥98.0% | 111.14 | 25 G
Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite derived from dietary choline and other trimethylamine-containing nutrients. It induces inflammation by activating the ROS/NLRP3 inflammasome. Additionally, it accelerates fibroblast-myofibroblast differentiation and triggers cardiac fibrosis through the activation of the TGF-β/smad2 signaling pathway. Trimethylamine N-oxide is also found in various marine organisms, where it offers protection against the adverse effects of temperature, salinity, high urea, and hydrostatic pressure.
- Induces inflammation by activating the ROS/NLRP3 inflammasome.
- Accelerates fibroblast-myofibroblast differentiation.
- Triggers cardiac fibrosis through activation of the TGF-β/smad2 signaling pathway.
- Provides protection against adverse effects of temperature, salinity, high urea, and hydrostatic pressure in marine organisms.
Medchemexpress LLC Trimethylamine N-oxide dihydrate | 62637-93-8 | 99.86% | 111.14 | 10 MG
Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite derived from dietary choline and other trimethylamine-containing nutrients. It is known to induce inflammation and accelerate fibroblast-myofibroblast differentiation. This compound is commonly found in marine organisms, providing protection against adverse effects of temperature, salinity, high urea, and hydrostatic pressure.
- Increases the size and migration of fibroblasts.
- Enhances TGF-β receptor I expression.
- Promotes Smad2 phosphorylation.
- Up-regulates α-SMA and collagen I expression.
- Decreases ubiquitination of TGF-βRI and inhibits smurf2 expression.
- Can be used in animal models to induce cardiovascular and metabolic diseases.
- Stimulates cardiac hypertrophy.
- Induces cardiac hypertrophy and fibrosis in SD rats.
Medchemexpress LLC Trimethylamine N-oxide dihydrate | 62637-93-8 | >98.0% | 111.14 | 10 MG
Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. It induces inflammation by activating the ROS/NLRP3 inflammasome. Additionally, it accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway.
- Gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients.
- Induces inflammation by activating the ROS/NLRP3 inflammasome.
- Accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway.
- Can be used in animal modeling to create cardiovascular and metabolic disease models.
- Found in tissues of various marine organisms, protecting against adverse effects of temperature, salinity, high urea, and hydrostatic pressure.
Medchemexpress LLC Trimethylamine N-oxide dihydrate | 62637-93-8 | 99.9% | 111.14 | 1 MG
Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite implicated in various biological processes. It is known to induce inflammation via ROS/NLRP3 inflammasome activation and accelerate fibroblast-myofibroblast differentiation, contributing to cardiac fibrosis through the TGF-β/smad2 signaling pathway. This product is for research use only.
- Induces inflammation and cardiac fibrosis.
- Accelerates fibroblast-myofibroblast differentiation.
- Modulates key signaling pathways including ROS/NLRP3 and TGF-β/smad2.
- Used in animal modeling for cardiovascular and metabolic diseases.
- Offers protective effects in marine organisms against environmental stressors.
Medchemexpress LLC Trimethylamine N-oxide (dihydrate) | 62637-93-8 | 98.0% | 111.14 | 100 MG
Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite derived from dietary choline and other trimethylamine-containing nutrients. It induces inflammation by activating the ROS/NLRP3 inflammasome. It also accelerates fibroblast-myofibroblast differentiation and triggers cardiac fibrosis by activating the TGF-β/smad2 signaling pathway. This compound is intended for research use only.
- Gut microbe-dependent metabolite.
- Induces inflammation via ROS/NLRP3 inflammasome activation.
- Accelerates fibroblast-myofibroblast differentiation.
- Induces cardiac fibrosis through TGF-β/smad2 signaling pathway activation.
- Useful for creating cardiovascular and metabolic disease models in animals.