Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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3,436 – 3,450 of 5,327 results

3,436

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 | C24H34ClN5O4S | 10MG

Yonkenafil hydrochloride is a research-grade phosphodiesterase 5 (PDE5) inhibitor supplied as the hydrochloride salt for biochemical and pharmacological studies. It is commonly used in in vitro and in vivo experiments to investigate PDE5-mediated signaling, vascular effects, and neuroprotection, and is typically handled as a DMSO-soluble compound.

Research-grade PDE5 inhibitor for biochemical and pharmacological studies.
High purity suitable for sensitive assays.
Hydrochloride salt form improves solubility in polar solvents.
Soluble in DMSO for easy assay preparation.
Reported molecular formula C24H34ClN5O4S and molecular weight 524.08.
Available in multiple small pack sizes for laboratory use.

Pricing & Availability

3,437

Medchemexpress LLC Bleomycin (hydrochloride) | 67763-87-5 | 99.5% | 5 MG

Bleomycin hydrochloride is a DNA synthesis inhibitor, a DNA damaging agent, and an antitumor antibiotic. It is primarily used for research purposes, including the creation of animal models of pulmonary fibrosis.

Inhibits DNA synthesis.
Acts as a DNA damaging agent.
Functions as an antitumor antibiotic.
Useful for creating animal models of pulmonary fibrosis.

Pricing & Availability

3,438

Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 | 10 MG

GB111-NH2 hydrochloride is a cysteine cathepsin inhibitor and can be used for cancer study.

It is a cysteine cathepsin inhibitor.
It can be used for cancer study.
It is for research use only.
It has a purity of 99.26%.
Its appearance is a white to off-white solid.
It should be shipped at room temperature in continental US and may vary elsewhere.
Storage conditions are -20°C, sealed storage, away from moisture and light.
In solvent, it should be stored at -80°C for 6 months or -20°C for 1 month (sealed storage, away from moisture and light).
It is soluble in DMSO at 125 mg/mL.

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3,439

Medchemexpress LLC Akalumine (hydrochloride) | 2558205-28-8 | 99.92% | 338.85 | 25 MG

AkaLumine hydrochloride is a D-luciferin analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. It emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc, offering high tissue-penetration and increased detection sensitivity for deep-tissue targets. It is intended for research use only and not for sale to patients.

D-luciferin analogue
Km of 2.06 μM for recombinant firefly luciferase protein
Emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc
High tissue-penetration
Increases detection sensitivity from deep-tissue targets

Pricing & Availability

3,440

Medchemexpress LLC 4-Pyridinemethanamine, N-[(3S)-1-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]-3-pyrrolidinyl] | 99.6% | 522.31 | 25 MG

OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. It significantly inhibits tumor growth in mouse xenograft models without detectable toxicity and regulates the production of γ-H2AX in cancer cells.

Potent protein methyltransferase SUV39H2 inhibitor (IC50 of 6.49 nM).
Shows significant inhibition of tumor growth in mouse xenograft models without detectable toxicity.
Regulates the production of γ-H2AX in cancer cells.

Pricing & Availability

3,441

Medchemexpress LLC Bobcat339 hydrochloride | 2436747-44-1 | 99.6% | 334.20 | 1 ML

Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of the TET enzyme, with IC50 values of 33 μM for TET1 and 73 μM for TET2. It is valuable in the field of epigenetics and serves as a foundation for developing new therapeutics targeting DNA methylation and gene transcription.

Potent and selective cytosine-based inhibitor of TET enzyme.
Useful in epigenetics research.
Serves as a starting point for new therapeutics targeting DNA methylation and gene transcription.
Inhibitory activity is directly related to Cu(II) content; the Bobcat339-copper mixture shows significantly higher TET inhibition than either alone.
Significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells at 10 μM for 24 hours.

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3,442

Medchemexpress LLC SKF-34288 hydrochloride (3-Mercaptopicolinic acid hydrochloride) | 320386-54-7 | 98.6% | 100 MG

SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor with a Ki of 2-9 μM. It acts as a potent hypoglycemic agent by inhibiting glucose synthesis and also inhibits Asn metabolism, leading to an increase in amino acids and amides.

Orally active PEPCK inhibitor (Ki: 2-9 μM)
Potent hypoglycemic agent that inhibits glucose synthesis
Inhibits Asn metabolism
Increases amino acids and amides
Reduces blood glucose in starved rats
Neutralizes Salbutamol-mediated hyperglycaemia in rabbits
Reduces pyruvate-induced blood glucose level in rats
Inhibits C2C12 cell proliferation
Induces myogenic differentiation of C2C12 cells

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3,443

Medchemexpress LLC EPZ020411 hydrochloride | 2070015-25-5 | 98.2% | 50 MG

EPZ020411 hydrochloride is a potent and selective inhibitor of protein arginine methyltransferase 6 (PRMT6) with an IC50 of 10 nM. It exhibits over 10-fold selectivity for PRMT6 compared to PRMT1 and PRMT8. This compound is valuable for cancer research and has demonstrated the ability to decrease H3R2 methylation in A375 cells, as well as reduce neomycin- and cisplatin-induced cell apoptosis, thereby increasing hair cell survival.

Selective inhibitor of PRMT6
IC50 of 10 nM for PRMT6
Over 10-fold selectivity for PRMT6 over PRMT1 and PRMT8
Can be used for cancer research
Decreases H3R2 methylation in A375 cells
Reduces neomycin- and cisplatin-induced cell apoptosis
Increases hair cell survival

Pricing & Availability

3,444

Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 25 MG

Midodrine hydrochloride is a selective and orally active adrenergic α1-receptor agonist. It strengthens vascular contraction and can be used for research on cardiovascular diseases such as orthostatic hypotension.

Strengthens vascular contraction
Increases p-AMPK and PPARδ expression in C2C12, HL1, and HepG2 cells
Increases Ca2+ in C2C12, HL1, and HepG2 cells
Increases maximal mitochondrial oxidative phosphorylation and ATP content in C2C12 cells
Reduces cellular lipid content in 3T3-L1 cells
Reduces platelet-activating factor (Paf)-induced death in mice
Shows anti-hypotensive effects in orthostatic hypotension rat models
Relieves hypertension in spontaneously hypertensive rat models

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3,445

Medchemexpress LLC Tivozanib hydrochloride hydrate | 682745-41-1 | 99.8% | 509.34 | 50 MG

Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib. It is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2, and 3, with IC50s of 30, 6.5, and 15 nM, respectively. It demonstrates antitumor efficacy.

Selective, orally active inhibitor for VEGFR-1, 2, and 3
Exhibits antitumor efficacy
Inhibits phosphorylation of VEGFR-1, VEGFR-2, and VEGFR-3 with IC50s of 0.16-0.24 nM in vitro
Inhibits VEGF-induced proliferation and migration of HUVECs in vitro
Selectively inhibits VEGF-stimulated phosphorylation of MAPKs in endothelial cells in vitro
Shows antitumor efficacy against breast, colon, hepatic, lung, ovarian, pancreatic, and prostate cancer in athymic mice models in vivo
Reversibly suppresses vascular permeability and angiogenesis in Calu-6 tumor bearing rats in vivo

Pricing & Availability

3,446

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML

Leelamine hydrochloride is a tricyclic diterpene molecule extracted from the bark of pine trees. It acts as a cannabinoid receptor type 1 (CB1) agonist and an inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, independent of androgen receptor status. It also suppresses the transcriptional activity of the androgen receptor, which regulates fatty acid synthesis.

Acts as a cannabinoid receptor type 1 (CB1) agonist
Inhibits SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells
Suppresses the transcriptional activity of the androgen receptor
Extracted from the bark of pine trees
Appears as a white to off-white solid
Store at -20°C in sealed conditions, away from moisture
For storage in solvent, store at -80°C for 6 months, or -20°C for 1 month in sealed conditions, away from moisture

Pricing & Availability

3,447

Medchemexpress LLC Voreloxin hydrochloride | 175519-16-1 | 99.6% | 437.90 | 25 MG

Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA double-strand breaks, G2 arrest, and apoptosis.

Induces G2 arrest partially through topoisomerase II in A549 lung cancer cell line.
Cytotoxic activity requires DNA intercalation.
Exhibits potent cytotoxic activity in AML cell lines, including MV4-11 and HL-60.
Shows additive or synergistic activity in acute leukemia cell lines when combined with cytarabine.
Causes accumulation of cells in the S and G2 phases of the cell cycle.
Induces bone marrow aplasia in vivo when combined with cytarabine.

Pricing & Availability

3,448

Medchemexpress LLC Mozavaptan hydrochloride | 138470-70-9 | MFCD11111965 | 99.9% | 464.0 g/mol | C27H30ClN3O2 | 5MG

Mozavaptan hydrochloride (OPC-31260 hydrochloride) is a benzazepine-derived, potent and selective vasopressin V2 receptor antagonist (reported IC50 ≈14 nM) used as a research chemical for studies of vasopressin signaling and conditions such as hyponatremia and SIADH. It is supplied as a white to off-white solid and is commonly available in small milligram quantities or as a DMSO solution for in vitro and pharmacology experiments. Molecular formula C27H30ClN3O2; molecular weight 464.0 g/mol; CAS 138470-70-9.

High purity suitable for research (≈99.9%)
Potent V2 receptor antagonist activity for pharmacology studies
Available in solid and DMSO solution formats
Compact packaging for small-scale experiments
Standard identifiers provided for traceability

Pricing & Availability

3,449

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g·mol⁻¹ | C24H34ClN5O4S | 10MM 1ML

Yonkenafil hydrochloride is a research-grade phosphodiesterase-5 (PDE5) inhibitor supplied as a high-purity hydrochloride salt for preclinical pharmacology and biochemical assays. It is available as a ready-to-use 10 mM DMSO solution or as a solid for reconstitution.

High purity suitable for research use.
Provided as 10 mM solution in DMSO or solid for reconstitution.
Molecular weight 524.08 g·mol⁻¹; chemical formula C24H34ClN5O4S.
Soluble in DMSO (≈190.8 mM); ultrasonic assistance may be required.
Solid storage at 4°C; solutions stable at -80°C (up to 6 months) or -20°C (up to 1 month).
Intended for preclinical studies involving PDE5 modulation.

Pricing & Availability

3,450

Medchemexpress LLC VU0357017 hydrochloride | 1135242-13-5 | MFCD17215959 | 99.9% | 369.89 | C18H28ClN3O3 | 10 MG

VU0357017 hydrochloride is a brain-penetrant, selective allosteric agonist of the M1 muscarinic acetylcholine receptor used as a research tool to probe M1 receptor pharmacology and signaling. Supplied as the hydrochloride salt, the compound is characterized by a defined molecular weight and high reported purity.

Potent M1 allosteric agonist with reported EC50 ≈ 477 nM.
Brain-penetrant small molecule suitable for in vitro and in vivo studies.
High chemical purity as provided by manufacturer.
Provided as a hydrochloride salt for improved solubility.
Available in small research pack sizes for laboratory use.

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Alcohols and polyols

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Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 | C24H34ClN5O4S | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bleomycin (hydrochloride) | 67763-87-5 | 99.5% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Akalumine (hydrochloride) | 2558205-28-8 | 99.92% | 338.85 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-Pyridinemethanamine, N-[(3S)-1-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]-3-pyrrolidinyl] | 99.6% | 522.31 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bobcat339 hydrochloride | 2436747-44-1 | 99.6% | 334.20 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SKF-34288 hydrochloride (3-Mercaptopicolinic acid hydrochloride) | 320386-54-7 | 98.6% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EPZ020411 hydrochloride | 2070015-25-5 | 98.2% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tivozanib hydrochloride hydrate | 682745-41-1 | 99.8% | 509.34 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Voreloxin hydrochloride | 175519-16-1 | 99.6% | 437.90 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mozavaptan hydrochloride | 138470-70-9 | MFCD11111965 | 99.9% | 464.0 g/mol | C27H30ClN3O2 | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g·mol⁻¹ | C24H34ClN5O4S | 10MM 1ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VU0357017 hydrochloride | 1135242-13-5 | MFCD17215959 | 99.9% | 369.89 | C18H28ClN3O3 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More