Thioureas
AdipoGen LY2835219
Chemical. CAS 1231930-82-7. Formula C27H32F2N8 . CH4O3S. MW 602.7. LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 CDK4 and CDK6 IC50s = 2 and 10 nM, respectively. Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds.
AdipoGen Salidroside
Chemical. CAS 10338-51-9. Formula C14H20O7. MW 300.3. Synthetic. Glycoside isolated from plants, most commonly from members of the genus Rhodiola, with many biological activities. Shown to have neuroprotective, antioxidant, antiviral, antidepressant, cardioprotective, anti-inflammatory and anticancer activity. Ameliorates insulin resistance.
Biomatik Corporation Indole-3-Butyric Acid [IBA]. Grade Biotechnology. Storage 4C. CAS 133-32-4
Indole-3-Butyric Acid [IBA]. Grade Biotechnology. Storage 4C. CAS 133-32-4
Biomatik Corporation Pepstatin A. Grade High Purity. Storage 4C. CAS 8913806
Pepstatin A. Grade High Purity. Storage 4C. CAS 8913806
AdipoGen Ozagrel
Chemical. CAS 82571-53-7. Formula C13H12N2O2. MW 228.2. Synthetic. Ozagrel, an antithrombic drug, is a potent and selective TXA Synthase thromboxane A2 TXAS inhibitor. Acts as a selective inhibitor of TXAS with an IC50=11nM. The beneficial effects of TXAS inhibition by ozagrel include improved motor coordination after experimental stroke, and antihypertensive effects in spontaneously hypertensive rats.
Biomatik Corporation Glucose Oxidase, 225U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
Glucose Oxidase, 225U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
Biomatik Corporation Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7
Leupeptin, Hemisulfate Salt. Grade Biotechnology. Storage -20C. CAS 103476-89-7
Biomatik Corporation Glucose Oxidase, 100U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
Glucose Oxidase, 100U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
Biomatik Corporation Glucose Oxidase, 225U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
Glucose Oxidase, 225U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
AdipoGen Elbasvir
Chemical. CAS 88321-09-9. Formula C17H30N2O5. MW 342.4. Aloxistatin is a cell permeable irreversible inhibitor of lysosomal and cytosolic cysteine proteases cathepsin B an L, calpain 1/2, papain and has diverse biological activities. It is an ethyl ester form of E-64c that inhibits calpain and the cysteine proteases cathepsins F, K, B, H, and L.
Biomatik Corporation Glucose Oxidase, 100U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
Glucose Oxidase, 100U/MG. Grade High Purity. Storage -20C. CAS 9001-37-0
Chem-Impex International, Inc. N-(2-Pyridinyl)thiourea | MFCD00041227 | 5G
N-(2-Pyridinyl)thiourea, MFCD00041227, 5G
AdipoGen Salidroside
Chemical. CAS 10338-51-9. Formula C14H20O7. MW 300.3. Synthetic. Glycoside isolated from plants, most commonly from members of the genus Rhodiola, with many biological activities. Shown to have neuroprotective, antioxidant, antiviral, antidepressant, cardioprotective, anti-inflammatory and anticancer activity. Ameliorates insulin resistance.
Matrix Scientific 1,3-DIBUTYL-2-THIOUREA-250G
1,3-Dibutyl-2-thiourea, 250g,C9H20N2S, MFCD00004926, mw 188.34, [109-46-6]
AdipoGen TPEN
Chemical. CAS 16858-02-9. Formula C26H28N6. MW 424.5. TPEN is a cell permeable metal ion chelator. TPEN is a chelator that has a high affinity for zinc Zn2, next to other transition metals Zn2 >Fe2 >Mn2 and is used in zinc treatment studies to limit intra- and extracellular concentrations of the mineral. TPEN has lower affinity for Ca2 and Mg2 and can also form complexes with other soft metal ions such as Cd2. In addition to a heavy metal chelator, TPEN is also known to be an apoptosis inducer. Depletion of zinc by TPEN induces apoptosis in several cell lines. TPEN shows anticancer activity through induction of caspase-dependent apoptosis, via reactive oxygen species ROS signaling mechanism and inhibiting cell autophagy. TPEN also inhibits RNA binding protein Lin28 and has been shown to be useful in extracting Abeta depostis from Alzheimers disease brain tissue.