Cinnamic acids and derivatives
eMolecules 871125-82-5 | 4-(4'-Fluorobenzyloxy)phenylboronic acid | Combi-Blocks, Inc. | MFCD07784403 | 246.040 | C13H12BFO3 | 95.000 | OB(O)c1ccc(OCc2ccc(F)cc2)cc1 | 25g | 603141609
4-(4'-Fluorobenzyloxy)phenylboronic acid | Combi-Blocks, Inc. | 871125-82-5 | MFCD07784403 | 246.040 | C13H12BFO3 | 95.000 | OB(O)c1ccc(OCc2ccc(F)cc2)cc1 | 25g | 603141609
eMolecules 1072951-98-4 | 4-(3'-Fluorobenzyloxy)phenylboronic acid | Combi-Blocks, Inc. | MFCD08276970 | 246.040 | C13H12BFO3 | 98.000 | OB(O)c1ccc(OCc2cccc(F)c2)cc1 | 5g | 603141610
4-(3'-Fluorobenzyloxy)phenylboronic acid | Combi-Blocks, Inc. | 1072951-98-4 | MFCD08276970 | 246.040 | C13H12BFO3 | 98.000 | OB(O)c1ccc(OCc2cccc(F)c2)cc1 | 5g | 603141610
Selleck Chemical LLC Curcumin analog C1
Curcumin analog C1 (Curcumin analog Compound C1) is a potent transcription factor EB (TFEB) activator with promise for the prevention or treatment of Alzheimer s disease
Medchemexpress LLC p-Coumaric acid (trans-4-hydroxycinnamic acid) | 501-98-4 | 164.16 | 10 G
p-Coumaric acid, an isomer of cinnamic acid, demonstrates diverse biological activities including antibacterial, anti-inflammatory, antioxidant, and anti-tumor effects. It has been shown to inhibit cell proliferation and promote apoptosis, making it a subject of interest in various research applications.
- Inhibits proliferation of A375 and B16 cells.
- Promotes cell apoptosis in human and mouse melanoma cells.
- Exhibits antibacterial activity against gram-negative and gram-positive bacteria.
- Reduces polyp incidence and precancerous lesions in animal models.
- Alleviates doxorubicin-induced nephrotoxicity by inhibiting oxidative stress, inflammation, and apoptosis.
- Modulates cell cycle progression and protein expression in A375 and B16 cells.
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | 99.86% | 164.16 | 10 G
2-Hydroxycinnamic acid is a chemical compound primarily used as a laboratory reagent. This product is supplied as a white to off-white solid with a molecular weight of 164.16 and a purity of 99.86% (HPLC). It is categorized as harmful if swallowed, causing skin and serious eye irritation, and potentially respiratory irritation. Proper handling and storage are crucial for safe use in laboratory environments.
- Appearance: White to off-white solid
- High purity: 99.86% (HPLC)
- Avoid inhalation and contact with eyes and skin
- Use only in areas with appropriate exhaust ventilation
- Wear protective gloves, eye protection, and suitable respirator
- Store tightly sealed in a cool, well-ventilated area, away from direct sunlight and ignition sources
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC α-cyano-4-hydroxycinnamic acid | 28166-41-8 | MFCD00004204 | 99.9% | 189.17 g·mol⁻¹ | C10H7NO3 | 100 MG
α-Cyano-4-hydroxycinnamic acid is a cinnamic acid derivative used as a research reagent and biochemical tool. It acts as a potent, non-competitive inhibitor of monocarboxylate transporters (MCTs) and is commonly used as a matrix in MALDI mass spectrometry and in studies of lactate transport and metabolism.
- Potent non-competitive inhibitor of monocarboxylate transporters.
- Suitable as a MALDI matrix for peptide analysis.
- High purity, 99.9% (reported 99.92%).
- Molecular weight 189.17 g·mol⁻¹.
- Supplied as a solid for laboratory use.
Sigma Aldrich Fine Chemicals Biosciences p-Coumaric acid 98.0 HPLC25G
P8 p-Coumaric acid 98.0 HPLC25G
Medchemexpress LLC Cinnamic acid | 621-82-9 | MFCD00004369 | 148.16 | 500 MG
Cinnamic acid is a chemical compound with potential applications in cancer intervention. It has shown dose-dependent growth inhibition in various tumor cells, including glioblastoma, melanoma, prostate, and lung carcinoma cells, with IC50 values ranging from 1 to 4.5 mM.
- Potential use in cancer intervention.
- Exhibits dose-dependent growth inhibition in tumor cells.
- Induces morphological changes consistent with melanocyte differentiation.
- Causes a dose-dependent loss of invasive capacity in treated tumor lines.
- Effective in glioblastoma, melanoma, prostate, and lung carcinoma cells.
Medchemexpress LLC cis-p-Coumaric acid | 4501-31-9 | 164.16 | 5 MG
cis-p-Coumaric acid, also known as cis-4-Hydroxycinnamic acid, is the cis-form of p-Coumaric acid. This compound is found in higher concentrations in viable groundnut seeds compared to non-viable ones.
- Exhibits oral activity.
- Inhibits cell proliferation.
- Promotes apoptosis.
Medchemexpress LLC 3-Methylcinnamic acid | 3029-79-6 | 99.77% | C10H10O2 | 5 G
3-Methylcinnamic acid is a drug intermediate utilized in the synthesis of various active compounds. This product is strictly for research use only and is not intended for patient administration. Careful handling and storage are recommended to maintain product integrity and safety.
- Store powder at -20°C for up to 3 years or at 4°C for 2 years.
- When in solvent, store at -80°C for 6 months or at -20°C for 1 month.
- Avoid breathing dust, fume, gas, mist, vapors, or spray.
- Wash hands thoroughly after handling.
- Use only outdoors or in a well-ventilated area.
- Wear appropriate protective equipment including gloves, clothing, and eye/face protection.
- May cause irritation to skin, eyes, and respiratory tract.
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 1 ML
p-Coumaric Acid Ethyl Ester, also known as Ethyl (E)-p-hydroxycinnamate or Ethyl trans-4-hydroxycinnamate, is a reversible, non-competitive inhibitor of tyrosinase. It quenches the enzyme's intrinsic fluorescence and alters the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain, without binding to the copper ion. This compound finds application in the development of various products, including medicines, cosmetics, and fruit preservation products that utilize pollen.
- Non-competitive and reversible tyrosinase inhibitor.
- Changes L-tyrosine binding affinity through conformational changes in tyrosinase's catalytic domain.
- Does not bind to the copper ion of the enzyme.
- Applicable in developing medicines.
- Used in cosmetic formulations.
- Utilized in fruit preservation products.
Medchemexpress LLC p-Coumaric acid ethyl ester | 7362-39-2 | MFCD00210460 | 50 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase. It quenches the intrinsic fluorescence of the enzyme and changes the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain of tyrosinase, without binding to the copper ion of the enzyme. This compound is utilized in the development of medicines, cosmetics, and for fruit preservation.
- Non-competitive, reversible inhibitor of tyrosinase
- Quenches the intrinsic fluorescence of the enzyme
- Induces conformational changes in the catalytic domain of tyrosinase without binding to copper ion
- Exhibits anti-platelet activity in rabbit platelet-rich plasma
- Utilized in medicine and cosmetic development
- Used for fruit preservation