Cinnamic acids and derivatives
TARGETMOL CHEMICALS INC Seviteronel R enantiomer 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Seviteronel R enantiomer (VT-464 R enantiomer) is a Seviteronel isomer produced during the manufacturing process. Purity 99.98%
Medchemexpress LLC Entacapone | 130929-57-6 | MFCD00866580 | 99.2% | 305.29 g/mol | C14H15N3O5 | 5 MG
Entacapone (Standard) is an analytical reference standard of entacapone provided for research and analytical use. Supplied in small quantitative sizes suitable for assay development, method validation, and quality control, the product includes batch documentation and a Certificate of Analysis reporting high purity. It is used as a reference material in studies involving COMT inhibition and related biochemical assays.
- Analytical standard for assay development and method validation.
- Available in small sizes, including a 5 mg vial.
- Certified purity approximately 99.2% (COA available).
- Useful for quality control and reference material applications.
- Molecular formula C14H15N3O5; molecular weight 305.29 g/mol.
Medchemexpress LLC Entacapone | 130929-57-6 | 99.97% | C14H15N3O5 | 50 MG
Entacapone is a potent, reversible, peripherally acting, and orally active catechol-O-methyltransferase (COMT) inhibitor. It is selective for COMT over other catecholamine metabolizing enzymes and can be used for Parkinson's disease research. Entacapone also inhibits FTO demethylation, making it relevant for metabolic disorders research.
- Inhibits COMT with IC50 values in the nanomolar range
- Demonstrates agonist activity at GPR35 in HT-29 and U2OS cells
- Enhances m6A on mRNA in Hep-G2 cells
- Decreases body weight and fat mass in obese mouse models
- Reduces total cholesterol, low-density lipoprotein cholesterol, and triglycerides
![Medchemexpress LLC Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester | 1439366-88-7 | 99.7% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231161.png-250.jpg)
Medchemexpress LLC Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester | 1439366-88-7 | 99.7% | 1 ML
ARN 077 (enantiomer) is the less-active stereoisomer of ARN 077 (also reported as URB913 enantiomer). It is supplied for research use and reported to inhibit rat NAAA with an IC50 of 3.53 μM for the less-active enantiomer. The compound is offered as a 10 mM solution in DMSO (1 mL) and as solid quantities for laboratory use.
- Supplied as 10 mM solution in DMSO, 1 mL, and as solids for flexibility in experiments.
- High reported purity (≈99.7%), suitable for research applications.
- Molecular formula C16H21NO4, molecular weight 291.34 g/mol.
- Reported CAS number 1439366-88-7 for unambiguous identification.
- Intended for research use only; not for human or diagnostic use.
eMolecules 1629972-11-7 | 3-Isobutoxy-4-methoxyphenylboronic acid | Combi-Blocks | MFCD12756417 | 224.060 | C11H17BO4 | 98.000 | COc1ccc(cc1OCC(C)C)B(O)O | 1g | 117524383
3-Isobutoxy-4-methoxyphenylboronic acid | Combi-Blocks | 1629972-11-7 | MFCD12756417 | 224.060 | C11H17BO4 | 98.000 | COc1ccc(cc1OCC(C)C)B(O)O | 1g | 117524383
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 10MG
SAR405 R enantiomer is the less active stereoisomer of the PIK3C3/Vps34 inhibitor SAR405, provided as a solid for in vitro research use only. It is suited for comparative pharmacology and control studies and includes handling and storage guidance for reliable experimental use.
- Less active enantiomer used as a comparative control in assays.
- High purity (≈99.9%).
- Solid, white to off-white appearance.
- Molecular formula C19H21ClF3N5O2; molecular weight 443.85.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Store powder at -20°C for long-term stability; store solutions at -80°C.
- Intended for laboratory research use only.
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 50 MG
m-Coumaric acid (Standard) is an analytical standard intended for research and analytical applications. It is a polyphenol metabolite from caffeic acid, formed by gut microflora, and is BBB-penetrant (blood-brain barrier) from chlorogenic acid.
- Stimulates cerebral nerves in vitro
- Evokes neurite outgrowth in hippocampal neuronal cells
- Promotes neuronal differentiation
- Increases spontaneous locomotor activity in mice
- Inhibits the oxidation of L-dopa by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Used as an analytical standard in HPLC, GC, and MS research experiments
Chem-Impex International, Inc. trans-Ferulic acid | 1135-24-6 | MFCD00004400 | 250G
trans-Ferulic acid, 1135-24-6, MFCD00004400, 250G
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 100 G
4-Methoxycinnamic acid is recognized as a natural phenylpropanoid found in A. preissii. It is used for research purposes only and is not sold to patients.
- Detected as natural phenylpropanoid in A. preissii.
- For research use only.
- Purity: 99.87%.
- Appears as a solid with an off-white to light yellow color.
- Initial source is an endogenous metabolite.
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 1 ML
p-Coumaric Acid Ethyl Ester, also known as Ethyl (E)-p-hydroxycinnamate or Ethyl trans-4-hydroxycinnamate, is a reversible, non-competitive inhibitor of tyrosinase. It quenches the enzyme's intrinsic fluorescence and alters the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain, without binding to the copper ion. This compound finds application in the development of various products, including medicines, cosmetics, and fruit preservation products that utilize pollen.
- Non-competitive and reversible tyrosinase inhibitor.
- Changes L-tyrosine binding affinity through conformational changes in tyrosinase's catalytic domain.
- Does not bind to the copper ion of the enzyme.
- Applicable in developing medicines.
- Used in cosmetic formulations.
- Utilized in fruit preservation products.
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 100 MG
Ferulic acid 4-O-sulfate, also known as Ferulic acid 4-sulfate, is a metabolite of Ferulic acid that has been observed to relax arteries and decrease blood pressure in mice.
- In vitro: This compound, at concentrations ranging from 0.1 to 30 μM, elicited significant concentration-dependent relaxations in the aorta, femoral, and saphenous arteries of mice.
- In vivo: When administered intravenously to male Swiss mice at dosages of 16.13 and 161.3 μg/kg, ferulic acid 4-O-sulfate demonstrated the ability to relax arteries and lower blood pressure, with a significant decrease in mean arterial pressure (MAP) observed immediately post-injection.
Medchemexpress LLC M-coumaric acid (standard) | 588-30-7 | 99.9% | 164.16 | 10 MG
M-coumaric acid (standard) | 588-30-7 | 99.9% | 164.16 | 10 MG