Coumarins and derivatives
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | MFCD00006856 | 500 G
4-Hydroxycoumarin is an orally active coumarin derivative and a versatile heterocyclic scaffold, utilized in the synthesis of various organic compounds. It possesses both electrophilic and nucleophilic properties.
- Orally active coumarin derivative
- Versatile heterocyclic scaffold for organic synthesis
- Possesses both electrophilic and nucleophilic properties
- Functions as an HIV protease inhibitor
- Acts as a tyrosine kinase inhibitor
- Exhibits anti-inflammatory effects
- Exhibits antibacterial effects
- Exhibits anti-tumor effects
Apexbio Technology LLC 3-Carboxy-7-Hydroxycoumarin 779-27-1 250mg
3-Carboxy-7-Hydroxycoumarin (CAS 779-27-1) is a coumarin-based fluorescent molecule It is characterized by blue fluorescence emission upon excitation with ultraviolet light Structurally it features a carboxyl group that enables conjugation via carbodiimide activation (e g EDAC-mediated formation of succinimidyl ester intermediates) allowing covalent attachment to amine-containing residues in proteins and nucleic acids Based on these properties 3-Carboxy-7-Hydroxycoumarin is commonly employed in biochemical research for fluorescent labeling including analysis of protein protein interactions nucleic acid visualization and biomolecule detection assays
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 1000 G
4-Hydroxycoumarin is an orally active coumarin derivative, a versatile heterocyclic scaffold used in the synthesis of various organic compounds. It exhibits both electrophilic and nucleophilic properties. It acts as an HIV protease inhibitor and tyrosine kinase inhibitor, and also possesses anti-inflammatory, antibacterial, and anti-tumor effects.
- Orally active coumarin derivative
- Versatile scaffold for organic synthesis
- Exhibits electrophilic and nucleophilic properties
- Acts as an HIV protease and tyrosine kinase inhibitor
- Possesses anti-inflammatory, antibacterial, and anti-tumor effects
- High purity white to off-white solid
- Shown to inhibit tumor growth in mouse melanoma models
- Reduces colitis symptoms in rat models
Medchemexpress LLC 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester | 134471-24-2 | >=96.0% | 1 G
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. It is a blue fluorescent dye used for labeling proteins and nucleic acids.
- Blue fluorescent dye
- Amine-reactive succinimidyl ester
- Used for labeling proteins and nucleic acids
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | 250 MG
6-Hydroxycoumarin is a coumarin exhibiting various biological activities, including anti-inflammatory, anti-pyretic, anti-oxidant, and vasodilator effects. It also demonstrates anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic, and antitumor properties.
- Exhibits anti-inflammatory activity
- Exhibits anti-pyretic activity
- Exhibits anti-oxidant activity
- Functions as a vasodilator
- Shows anti-amoebic activity
- Shows anti-bacterial activity
- Shows anti-fungal activity
- Acts as a bacteriostatic agent
- Exhibits antitumor activity
- For research use only
Medchemexpress LLC 6-Hydroxycoumarin | 6093-68-1 | 1 ML
6-Hydroxycoumarin is a coumarin compound known for its diverse biological activities. It exhibits anti-inflammatory, anti-pyretic, anti-oxidant, and vasodilator properties. This compound also demonstrates anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic, and antitumor effects.
- Exhibits anti-inflammatory properties
- Acts as an anti-pyretic agent
- Functions as an anti-oxidant
- Demonstrates vasodilator effects
- Shows anti-amoebic activity
- Possesses anti-bacterial and anti-fungal properties
- Has bacteriostatic effects
- Exhibits antitumor activity
Medchemexpress LLC AZP-531 | 1088543-62-7 | 99.8% | 962.02 | 1 MG
AZP-531 is an analogue of unacylated ghrelin for research use, designed to improve glycaemic control and reduce weight. It shows survival effects on pancreatic β-cells and human pancreatic islets, and is highly stable in human plasma in vitro with no degradation after one day at 37°C.
- Exhibits survival effects on pancreatic β-cells and human pancreatic islets.
- Stable in human plasma in vitro at 37°C for one day.
- Prevents high-fat diet-induced weight gain, proinflammatory effects, and prediabetic metabolic state in mice.
- Stimulates mitochondrial function markers in brown adipose tissue.
- Well-tolerated in clinical trials; improves glucose without increasing insulin.
- Reduces mean body weight and HbA1c in clinical trials.
Selleck Chemical LLC Palomid 529 (P529) S2238-1g
Palomid 529 (P529 SG 00529) inhibits both the mTORC1 and mTORC2 complexes reduces phosphorylation of pAktS473 pGSK3 S9 and pS6 Phase 1
Medchemexpress LLC 7-Hydroxycoumarin-4-acetic acid | 6950-82-9 | 1 G
7-Hydroxycoumarin-4-acetic acid is a pH-indicator dye that covalently binds to bovine serum albumin (BSA). This solid, white to off-white compound is suitable for various laboratory applications.
- Used as a pH-indicator dye
- Covalently binds to bovine serum albumin (BSA)
- Solid, white to off-white appearance
- Suitable for research use
Medchemexpress LLC 4-Hydroxycoumarin | 1076-38-6 | 25 MG
4-Hydroxycoumarin is an orally active coumarin derivative and a versatile heterocyclic scaffold used in the synthesis of various organic compounds. It possesses both electrophilic and nucleophilic properties, acting as an HIV protease inhibitor and a tyrosine kinase inhibitor. This compound also demonstrates anti-inflammatory, antibacterial, and anti-tumor effects.
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 100 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase. It exhibits photoprotective effects on sea urchin zygotes and embryos, and also demonstrates free radical scavenging activities.
- Inhibits tyrosinase (IC50 for recombinant human tyrosinase of 26 μM) and lipoxygenase (IC50 for LOX of 9.5 μM).
- Displays DPPH free radical scavenging activity (IC50 = 31.2 μM).
- Provides photoprotective effects on sea urchin zygotes and embryos.
- Can be formulated into a vesicle delivery system for efficient local accumulation in the skin.