Flavonoids
Cayman Chemical Tangeretin Neurochemicals
A polymethoxylated flavone isolated from citrus peels; inhibits signaling in cancer cells, reducing ERK signaling in T47D breast cancer cells (IC50 ~3 μM)
Medchemexpress LLC Myricetin | 529-44-2 | MFCD00006827 | 98.5% | 318.24 g/mol | C15H10O8 | 10 MG
Myricetin is an analytical reference standard of myricetin (CAS 529-44-2), a plant-derived flavonoid used as a reference material in analytical and research applications. Supplied as a high-purity solid suitable for HPLC, method validation, and quantitative analysis.
- Analytical reference standard for HPLC and method validation.
- High purity: 98.5% assay.
- Provided in small, controlled pack sizes for accurate weighing.
- Known molecular weight and formula for identification and calibration.
- Intended for research and analytical applications.
Medchemexpress LLC (±)-Catechin | 7295-85-4 | 99.5% | 250 MG
(±)-Catechin | 7295-85-4 | 99.5% | 250 MG
Apexbio Technology LLC Luteolin 491-70-3 10mM (in 1mL DMSO)
Luteolin (CAS 491-70-3) is a naturally occurring flavonoid characterized by anti-inflammatory antioxidant and chemopreventive properties Mechanistically it suppresses lipopolysaccharide (LPS)-mediated inflammation by inhibiting production of pro-inflammatory cytokines such as TNF- and IL-6 reducing inducible nitric oxide synthesis and blocking NF- B and AP-1 signaling pathways Additionally luteolin impedes TNF- -induced cyclooxygenase-2 (COX-2) expression In preclinical in vivo studies it exhibits antiproliferative activity against tumor cell proliferation exemplified by growth inhibition in Lewis lung carcinoma models Consequently luteolin is widely investigated in biomedical research targeting inflammation oxidative stress and cancer biology
TARGETMOL CHEMICALS INC LUTEOLIN 7-O-GLUCURONIDE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) possesses antioxidant activities. purity: 99%
Apexbio Technology LLC (-)-epicatechin 490-46-0 10mg
(-)-Epicatechin (CAS 490-46-0) is a flavonoid compound known for inducing pancreatic -cell regeneration and modulating nitric oxide (NO) metabolism It inhibits nitric oxide-related nitrite formation induced by interferon- and lipopolysaccharide in mouse macrophages and reduces peroxynitrite-mediated tyrosine nitration in HL-60 human leukemia cells Additionally in human endothelial cells (HUVECs) it enhances NO production displaying vasodilatory properties In diabetic rat models (alloxan-induced) (-)-epicatechin administration promotes -cell recovery reduces hyperglycemia and prevents -cell necrosis This profile underscores its research relevance for diabetes and vascular biology investigations
Apexbio Technology LLC AMG 487 473719-41-4 100mg
AMG 487 (CAS 473719-41-4) is a selective small molecule antagonist targeting chemokine receptor CXCR3 a G protein-coupled receptor involved in immune cell migration It competitively inhibits CXCR3 binding to its cognate chemokines including IP-10 and ITAC with IC50 values reported at approximately 8 nM and 8 2 nM respectively Cell-based assays indicate AMG 487 can effectively impede IP-10 ITAC and MIG-mediated chemotaxis and ITAC-induced calcium mobilization AMG 487 is metabolized via CYP3A4 and CYP3A5 to metabolites one of which (M2) inhibits CYP3A Given these characteristics AMG 487 provides a valuable pharmacological tool for investigating CXCR3 functions in inflammatory and immunological research
Apexbio Technology LLC (-)-Epigallocatechin gallate (EGCG) 989-51-5 500mg
(-)-Epigallocatechin gallate (EGCG CAS 989-51-5) is a major catechin component derived from green tea comprising approximately 59% of total catechins EGCG exhibits antioxidant antiangiogenic antitumor and antiviral properties by modulating cellular signaling pathways involved in apoptosis induction cell cycle arrest and tumorigenesis inhibition It suppresses viral replication in pathogens including HCV HIV-1 HBV HSV-1/2 EBV adenovirus influenza virus and enterovirus and inhibits enzyme targets such as DNA methyltransferases (DNMTs) proteases and DHFR EGCG is utilized widely in biomedical research examining chemoprevention mechanisms and therapeutic potential in cancers such as hepatic gastric dermal pulmonary breast and colorectal malignancies
TARGETMOL CHEMICALS INC CHRYSIN-7-O-GLUCURONIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Chrysin-7-O-glucuronide (Chrysin 7-O-beta-D-glucopyranuronoside) is a natural product with antioxidant activitypurity: 99%
AdipoGen -Catechin hydrate
Chemical. CAS 225937-10-0 or 88191-48-4. Formula C15H14O6 . H2O. MW 290.3 . 18.0. Isolated from Uncaria rhynchophylla. Specific histidine decarboxylase inhibitor. Anti-inflammatory. COX-1 inhibitor. Antioxidant flavonoid. Free radical scavenger. Inhibits lipid peroxidation. Antimetastatic and anticancer compound. Antiangiogenic. Anti-osteoporotic. Antibacterial and antifungal. Neuroprotective. Mono oxidase B inhibitor. Apoptosis and cell cycle arrest inducer. JNK phosphorylation inhibitor. Antispasmodic. Insulin-mimetic.
Apexbio Technology LLC (-)-epicatechin 490-46-0 10mM (in 1mL DMSO)
(-)-Epicatechin (CAS 490-46-0) is a flavonoid compound known for inducing pancreatic -cell regeneration and modulating nitric oxide (NO) metabolism It inhibits nitric oxide-related nitrite formation induced by interferon- and lipopolysaccharide in mouse macrophages and reduces peroxynitrite-mediated tyrosine nitration in HL-60 human leukemia cells Additionally in human endothelial cells (HUVECs) it enhances NO production displaying vasodilatory properties In diabetic rat models (alloxan-induced) (-)-epicatechin administration promotes -cell recovery reduces hyperglycemia and prevents -cell necrosis This profile underscores its research relevance for diabetes and vascular biology investigations
Indofine Chemical DAIDZEIN, Flavonoid & Coumarins, 486-66-8, 98+%, 100 mg
DAIDZEIN, Flavonoid & Coumarins, 486-66-8, 98+%, 100 mg
Apexbio Technology LLC (-)-epicatechin 490-46-0 5mg
(-)-Epicatechin (CAS 490-46-0) is a flavonoid compound known for inducing pancreatic -cell regeneration and modulating nitric oxide (NO) metabolism It inhibits nitric oxide-related nitrite formation induced by interferon- and lipopolysaccharide in mouse macrophages and reduces peroxynitrite-mediated tyrosine nitration in HL-60 human leukemia cells Additionally in human endothelial cells (HUVECs) it enhances NO production displaying vasodilatory properties In diabetic rat models (alloxan-induced) (-)-epicatechin administration promotes -cell recovery reduces hyperglycemia and prevents -cell necrosis This profile underscores its research relevance for diabetes and vascular biology investigations
TARGETMOL CHEMICALS INC PHILLYRIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Phillyrin (Forsythin) is a novel AMPK activator has anti-obesity effects in nutritive obesity mice it can prevent lipid accumulation in HepG2 cells by blocking the expression of SREBP-1c and FAS through LKB1/AMPK activation. Phillyrin(Forsythin) may be a new preventive agent of acute lung injury in the clinical setting it potentially contributes to the suppression of the activation of MAPK and NF-(kappa)B pathways it also has protective effects on H2O2-induced oxidative stress and apoptosis in PC12 cells. purity: 99%