Flavonoids
Apexbio Technology LLC Rutin 153-18-4 10mM (in 1mL DMSO)
Rutin (CAS 153-18-4) is a naturally occurring flavonoid glycoside that can be isolated from Sophora japonica L It exhibits antioxidant and anti-inflammatory activities primarily by scavenging reactive oxygen species modulating signaling pathways related to oxidative stress and inhibiting pro-inflammatory cytokine production Due to its pharmacological profile rutin is utilized extensively in biomedical research to investigate protective effects against cardiovascular dysfunction vascular permeability and inflammation-related conditions It is soluble in heated water methanol ethanol pyridine and alkaline environments and should be stored under cool dry and sealed conditions
Sigma Aldrich Fine Chemicals Biosciences Luteolin 98 TLC powder50MG
Luteolin (3AE 4AE 5AE 7AE-tetrahydroxyflavone) a polyphenolic compound belongs to flavones subclass of flavonoids. Luteolin is commonly found in plants like celery green peppers and chamomile tea. Luteolin is one of the major flavonoids present in the flower extract of Hieracium pannosum Boiss aerial part of Dracocephalum kotschyi and contributes to the antioxidant potential of the plant. Luteolin possesses antioxidant anti-inflammatory properties and exerts anti-tumor potential primarily through apoptosis. Luteolin exerts its apoptotic activity through downregulation of protein kinase B (Akt) pathway leading to caspase mediated apoptosis. Luteolin also resensitizes cancer cells to therapeutics. Luteolin regulates the inflammatory genes and reduces nitric oxide and inflammatory cytokine production. The anti-inflammatory property of luteolin implicates it as a potential therapeutic agent for the neurodegenerative disease like Alzheimer disease. In plants luteolin induces nodu
Medchemexpress LLC 5-Hydroxyflavone | 491-78-1 | 99.8% | 238.24 | 100 MG
5-Hydroxyflavone | 491-78-1 | 99.8% | 238.24 | 100 MG
Medchemexpress LLC Isovitexin 7-O-rutinoside | 212271-10-8 | 740.66 | 5 MG
Isovitexin 7-O-rutinoside is an anti-inflammatory agent that can be isolated from the Mongolian anti-hepatic plant Dianthus versicolor.
- Acts as an anti-inflammatory agent
TARGETMOL CHEMICALS INC AST 487 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AST 487 (NVP-AST 487) is a RET kinase inhibitor inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3. purity: 99%
Medchemexpress LLC 5,7-dimethoxyflavone | 21392-57-4 | MFCD00016943 | 282.29 g/mol | C17H14O4 | 10 MG
5,7-Dimethoxyflavone is a dimethoxylated flavone found in Kaempferia parviflora. It is supplied as a research and analytical reagent for laboratory use and serves as an analytical standard and reference material. Reported activities include inhibition of cytochrome P450 3A enzymes and breast cancer resistance protein (BCRP).
- CAS number: 21392-57-4.
- Molecular formula: C17H14O4.
- Molecular weight: 282.29 g/mol.
- Supplied as a small solid quantity suitable for analytical testing (10 MG).
- Intended for research and analytical use only; not for human use.
- Store protected from light; solid storage at 4°C; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
Medchemexpress LLC Catechin-13C3 | 154-23-4 | MFCD15144883 | 293.25 | 1 MG
Catechin-13C3 is a 13C-labeled version of Catechin, a natural antioxidant found in various plants. This compound inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. This stable isotope-labeled compound is valuable for research applications.
- Labeled stable isotope
- Useful for metabolic studies
- Ideal for quantitative analysis
- Suitable for tracking biochemical pathways
Medchemexpress LLC Apigenin | 520-36-5 | 270.24 | 5 MG
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM. It inhibits cell proliferation in SGC-7901 cells in a dose- and time-dependent manner and possesses a broad spectrum of biological properties including antioxidative, anti-inflammatory, anticancer, and neuroprotective effects.
- Inhibits cell proliferation
- Suppresses clone formation of SGC-7901 cells
- Alleviates adriamycin-induced myocardial injury
- Reduces serum aspartate amino transferase release
- Reduces serum lactate dehydrogenase release
- Reduces serum creatine kinase contents
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 462.36 | 1 MG
Luteolin 7-O-glucuronide inhibits Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, and 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. It also inhibits NO production and mRNA expression of inflammatory mediators (COX-2, IL-6, IL-1β, and TNF-α) as well as NF-κB, p38, and JNK activation in LPS-stimulated RAW 264.7 macrophages. In a mouse sleep deprivation model, this compound improved depression-like and stress coping behaviors.
- Inhibits matrix metalloproteinases (MMPs) activities.
- Reduces NO production and inflammatory mediators.
- Inhibits NF-κB, p38, and JNK activation.
- Improves depression-like and stress coping behaviors.
- Suitable for in vitro and in vivo studies.
Medchemexpress LLC Myricetin 3-O-α-L-arabinopyranoside | 132679-85-7 | 450.35 | 1 MG
Myricetin 3-O-α-L-arabinopyranoside is a quercetin derivative and plant flavonoid. It has antioxidant, antibacterial, and antiurease effects.
- Inhibits A2E photooxidation-induced RPE cell death
- Protective against retinal degeneration
- Protects against blue light-induced damage in RPE cells and mouse models
Medchemexpress LLC Catechin 7-O-β-D-glucopyranoside | 65597-47-9 | 452.41 | 1 MG
Catechin 7-O-β-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. It demonstrates antioxidant and anti-inflammatory activities, and mitigates mitochondrial dysfunction. This product can be utilized in research pertaining to intestinal inflammatory diseases.
- Exhibits antioxidant and anti-inflammatory activities
- Attenuates mitochondrial dysfunction
- Protective effect against Streptozotocin-induced cell damage
- Mild protective effect against LPS/D-GalN induced lethality in mice
- Prevents intestinal inflammatory damages in rat colitis models
Sigma Aldrich Fine Chemicals Biosciences Naringin >=95% (HPLC) | 10236-47-2 | MFCD00148888 | 100G
Naringin >=95% (HPLC) | Purity: >=95% (HPLC) | Mol Wt: 580.53 | 10236-47-2 | MFCD00148888 | 100G
Medchemexpress LLC Catechin | 154-23-4 | 290.27 | 5 MG
Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
- 15+ Cited publications
- Also known as (+)-Catechin; Cianidanol; Catechuic acid
- Targeting COX apoptosis, influenza virus, and endogenous metabolite pathways
- Research area: Cancer
- Structural classification: Anti-aging, Camellia sinensis (L.) O. Ktze. plants, endogenous metabolite, flavonoids, sunscreen, flavanols, phenols, polyphenols
- Application fields: Cosmetic research, disease research fields
- Source classification: Theaceae
Medchemexpress LLC Gallocatechin gallate | 5127-64-0 | 1 MG
Gallocatechin gallate is a flavonoids product that can be isolated from the herbs of Celastrus orbiculatus. It is intended for research use only.
- Molecular weight: 458.37
- Formula: C22H18O11
- Appearance: Solid
- Color: White to off-white
- Purity: 98%
- Storage: -20°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light).
- Structure classification: Flavonoids
- Initial source: Plants, celastraceae, celastrus, Celastrus orbiculatus Thunb.