Flavonoids
Medchemexpress LLC 4'-Hydroxyflavanone | 6515-37-3 | MFCD00006734 | 5 MG
4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. It is a synthetic analogue of flavanone and has potential for hepatic steatosis and dyslipidemia research.
- Inhibitor of SREBP maturation
- Inhibitor of lipid synthesis
- Synthetic analogue of flavanone
- Potential for hepatic steatosis research
- Potential for dyslipidemia research
Medchemexpress LLC Kaempferol 3-O-rutinoside 7-O-glucoside | 34336-18-0 | 5 MG
Kaempferol 3-O-rutinoside 7-O-glucoside is a flavonoid glycoside found in red tomato, as well as organisms such as Crocus minimus and Crocus chrysanthus. It is intended for research use only.
- Purity: 99.67%
- Molecular formula: C33H40O20
- Molecular weight: 756.66
- Appearance: Off-white to light yellow solid
- Classified as a flavonoid, flavonol, phenol, and polyphenol
Medchemexpress LLC 6-Methoxyflavone 50mg
6-Methoxyflavone is an orally active methoxyflavone 6-Methoxyflavone suppresses neuroinflammation in microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF- B dependent pathways and the activation of HO-1/NQO-1 signaling 6-Methoxyflavone induces S-phase arrest through the CCNA2/CDK2/p21CIP1 signaling pathway and activates the PERK/EIF2a/ATF4/CHOP pathway in HeLa cells 6-Methoxyflavone acts as a Flumazenil (HY-B0009)-insensitive positive allosteric modulator at human recombinant 1 2 2L and 2 2 2L GABA receptors 6-Methoxyflavone inhibits NFAT Translocation into the nucleus and suppresses T cell activation 6-Methoxyflavone partially restores chronic ethanol-induced behavioral deficits in mice 6-Methoxyflavone antagonizes chronic constriction injury and diabetes associated neuropathic nociception expression 6-Methoxyflavone can be used for the study of cancer inflammation and neurological diseases[1][2][3][4][5][6][7][8]
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 98.7% | 462.36 | C21H18O12 | 10 MG
Luteolin 7-O-glucuronide is a flavone glycoside used as a research reagent to study matrix metalloproteinase (MMP) inhibition and inflammation-related pathways. It is supplied as a light-yellow solid and as a DMSO solution, and is provided at high purity for biochemical assays and analytical standards.
- Cas number: 29741-10-4.
- Molecular weight: 462.36.
- Typical purity: 98.7% (batch level).
- Physical forms: solid and 10 mM solution in DMSO.
- Typical package sizes include 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.
- Common applications: enzymatic inhibition assays and analytical standardization.
Medchemexpress LLC Luteolin-7-rutinoside | 20633-84-5 | 1 MG
Luteolin-7-rutinoside is a flavonoid glycoside exhibiting both anti-arthritic and antifungal activities. It can be used as a combination therapy for the treatment of fungal arthritis due to C. albicans infection. Its suppressive activity is dose-dependent, and it shifts the Th1-Th2 balance away from Th1- towards Th2-type responses, while also inhibiting nitric oxide (NO) production from macrophages.
- Anti-arthritic activity
- Antifungal activity
- Can be used for treatment of fungal arthritis due to C. albicans infection
- Suppressive activity on T cell proliferation is dose-dependent
- Shifts Th1-Th2 balance away from Th1- towards Th2-type responses
- Inhibits nitric oxide (NO) production from macrophages
Medchemexpress LLC Nicotiflorin | 17650-84-9 | MFCD03427292 | 99.9% | 594.52 | C27H30O15 | 10 MG
Nicotiflorin is a kaempferol-derived flavonoid glycoside extracted from Carthamus tinctorius. It exhibits antiglycation activity and has reported neuroprotective effects in preclinical studies. Supplied as a research-grade solid, it is intended for biochemical and neuropharmacology investigations.
- High purity: 99.85% (analytical)
- Molecular formula: C27H30O15; molecular weight: 594.52
- Physical form: light yellow solid
- Storage: solid at 4°C, protect from light; solutions stored at -20°C to -80°C
- Available in small solid packs suitable for research use
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | MFCD00006835 | 50 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This orally active compound also inhibits PKM2, COX-2, and 5-LOX, and has demonstrated antioxidant activity and efficacy in various animal models.
- Isolated from *Clerodendrum phlomidis*
- Exhibits anti-inflammatory activity
- Protects renal cells from nicotine-associated cytotoxicity
- Inhibits PKM2, COX-2, and 5-LOX
- Orally active
- Reduces malondialdehyde (MDA) and reactive oxygen species (ROS) levels
- Increases superoxide dismutase (SOD) and glutathione (GSH) levels
- Ameliorates ischemia/reperfusion injury
- Improves high-fat diet-induced non-alcoholic fatty liver disease and obesity
- Purity of 99.89%
- Appearance is a white to off-white solid
Medchemexpress LLC Fustin | 20725-03-5 | 1 MG
Fustin ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β (Aβ) inhibitor. It increases acetylcholine (ACh) levels, choline acetyltransferase (ChAT) activity, and ChAT gene induced by Aβ (1-42). It also decreases acetyl cholinesterase (AChE) activity and AChE gene expression induced by Aβ (1-42). Fustin increases muscarinic M1 receptor gene expression and muscarinic M1 receptor binding activity. It can be used for Alzheimer's disease research.
- Potent amyloid β (Aβ) inhibitor.
- Increases acetylcholine (ACh) levels and choline acetyltransferase (ChAT) activity.
- Decreases acetylcholinesterase (AChE) activity.
- Enhances muscarinic M1 receptor expression and binding.
- Suitable for Alzheimer's disease research.
Medchemexpress LLC (+)-epicatechin (dexepicatechin) | 35323-91-2 | MFCD00075648 | 99.6% | 10 MG
(+)-Epicatechin is a chiral catechin and polyphenolic antioxidant supplied as a research reagent. It is commonly used in biochemical and analytical assays to evaluate antioxidant activity and enzyme inhibition. The compound is a white to off-white solid with molecular formula C15H14O6 and a molecular weight of 290.27 g/mol. Purity is typically reported at about 99.6%.
- High purity suitable for analytical applications
- Solid form convenient for storage and handling
- Used in antioxidant and cyclooxygenase inhibition studies
- Soluble in common organic solvents for stock solutions
- Provided in a small quantity suitable for early-stage experiments
Medchemexpress LLC Catechin (Standard) | 154-23-4 | 290.27 | 50 MG
Catechin (Standard) is an analytical standard intended for research and analytical applications. It inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM and serves as a reference standard assay.
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Compatible with HPLC, GC, and MS techniques
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 1 ML
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity through the ERK/Nrf2/HO-1 pathway. This compound inhibits PKM2, COX-2, and 5-LOX, and is orally active.
- Inhibits nicotine-induced cytotoxicity and reduces ROS production in renal cells
- Inhibits EV71 3C protease, blocking viral replication
- Decreases malondialdehyde and ROS levels, increases SOD and GSH levels in HepG2 cells
- Inhibits inflammatory cytokines and reduces myocardial injury markers in rat models
- Ameliorates Paclitaxel or Vinorelbine-induced neuropathic pain in mice models
- Reduces fat accumulation, improves hepatic steatosis and oxidative stress in NAFLD models
Medchemexpress LLC (-)-Epigallocatechin Gallate (Standard) | 989-51-5 | 98.05% | 458.37 | 25 MG
(-)-Epigallocatechin Gallate (Standard) is the analytical standard of (-)-Epigallocatechin Gallate, intended for research and analytical applications. It is a major polyphenol in green tea that can inhibit cell proliferation and induce cell apoptosis. It also inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity and possesses potent anticancer, antioxidant, and anti-inflammatory properties against various cancers like colorectal cancer, myeloid leukemia, and thyroid carcinoma.
- Analytical standard for research and analytical applications
- Inhibits cell proliferation and induces cell apoptosis
- Inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity
- Possesses potent anticancer, antioxidant, and anti-inflammatory properties
- Used as a reference standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
Medchemexpress LLC Kaempferol 3,7,4'-trimethyl ether | 15486-34-7 | 5 MG
Kaempferol 3,7,4'-trimethyl ether is a flavonol aglycone isolated from the leaves of *Siparuna gigantotepala*. It exhibits antioxidant activity and is intended for research use only.
- 98.0% purity
- Molecular weight: 328.32
- Chemical formula: C18H16O6
- Solid appearance
- Light yellow to yellow color
- Classified as a flavonoid, flavonol, phenol, and monophenol
- Isolated from plants
- Demonstrates cytotoxicity against human A549, HT-29, and HeLa cells
Medchemexpress LLC 7-Methoxyflavone | 22395-22-8 | MFCD00017462 | 100 MG
7-Methoxyflavone is a flavonoid compound isolated from Zornia brasiliensis. It binds to human serum albumin and acts as an aromatase inhibitor. It possesses peripheral analgesic and certain antitumor activities, being effective against chemical pain but not thermal pain.
- Isolated from Zornia brasiliensis
- Binds to human serum albumin
- Acts as an aromatase inhibitor
- Exhibits peripheral analgesic activity
- Exhibits antitumor activities
- Effective against chemical pain
Alkali Scientific Myricetin, 500 Mg
Myricetin (MYR004 CP) is a flavonoid widely used in laboratory research for its antioxidant, anti-inflammatory, and anticancer properties. The 500mg bottle is suitable for large-scale experiments and extended research studies. Myricetin has been shown to exert several beneficial effects on human health, including its potential to mitigate oxidative stress, reduce inflammation, and inhibit cancer cell growth. In addition to its use in studying cellular mechanisms, myricetin is also employed in the development of natural therapeutic agents. This high-concentration formulation is essential for researchers conducting long-term studies on flavonoid-based health applications.