Flavonoids
Medchemexpress LLC 3',4'-Dimethoxy-alpha-naphthoflavone | 14756-24-2 | MFCD00143008 | 98.5% | 332.35 g·mol^-1 | C21H16O4 | 10 MG
DiMNF (3',4'-Dimethoxy-alpha-naphthoflavone) is a small-molecule aryl hydrocarbon receptor (AHR) modulator supplied for research use. It is offered as a solid and as concentrated DMSO solutions for in vitro biochemical and cell-based assays involving AHR signaling and CYP activity.
- Selective aryl hydrocarbon receptor (AHR) modulator for research applications.
- High purity (≈98.5%) to support reproducible experimental results.
- Molecular formula C21H16O4 and molecular weight 332.35 g·mol^-1.
- Available in multiple pack sizes, including small solid quantities and DMSO solutions.
- Supplied as a solid with optional preprepared DMSO solutions for convenient dosing.
Medchemexpress LLC Neohesperidin (Hesperetin 7-O-neohesperidoside) | 13241-33-3 | 98.7% | 610.56 | 500 MG
Neohesperidin is a flavonoid compound found in citrus plants, known for its antioxidant and anti-inflammatory properties. It has been shown to upregulate the Wnt/β-catenin signaling pathway and induce apoptosis in human breast adenocarcinoma MDA-MB-231 cells. In vivo, it significantly inhibits HCl/ethanol-induced gastric lesions and improves glucose tolerance and insulin sensitivity in diabetic mice.
- Possesses antioxidant and anti-inflammatory properties.
- Upregulates the Wnt/β-catenin signaling pathway.
- Induces apoptosis in human breast adenocarcinoma MDA-MB-231 cells.
- Inhibits HCl/ethanol-induced gastric lesions.
- Improves oral glucose tolerance and insulin sensitivity.
Cayman Chemical Hesperetin Natural Products Ex
A flavonoid with diverse biological activities; reduces ApoB protein levels, ACAT2 expression, and LDL degradation in HepG2 cells from 10-200 µM; inhibits IgG-induced β-hexosaminidase release from RBL-2H3 cells (IC50 = 0.099 mg/ml); inhibits LPS-induced NO production and reduces levels of iNOS, IL-6, and IL-1β in BV-2 microglial cells; inhibits passive cutaneous anaphylaxis in mice at 5 mg/kg; reduces body weight loss, colon shortening, and ulcer severity in a mouse model of TNBS-induced ulcerative colitis; reduces cortical and hippocampal neuronal apoptosis and increases time spent in the target quadrant in the Morris water maze in a mouse model of LPS-induced neuronal inflammation
Medchemexpress LLC 4'-methoxyflavone | 4143-74-2 | MFCD00016934 | 99.6% | C16H12O3 | 10MG
4'-Methoxyflavone is a synthetic flavone derivative used as a research reagent in biochemical and cell biology studies. It exhibits antioxidant and antiproliferative activity and is provided as a high-purity solid for laboratory assays. Intended for in vitro research use only.
- High purity suitable for analytical and biological studies.
- Available in small milligram quantities for assay development.
- Soluble in common organic solvents for solution preparation.
- Reported antioxidant and antiproliferative properties.
- Not for human or clinical use; for laboratory research only.
Medchemexpress LLC 5-methoxyflavone | 42079-78-7 | MFCD00016942 | 100.0% | 252.26 g·mol⁻¹ | C16H12O3 | 1 ML
5-Methoxyflavone is a flavonoid-class small molecule (C16H12O3, MW 252.26 g·mol⁻¹) reported as a DNA polymerase-beta inhibitor and a neuroprotective agent. It is supplied as both a solid and a ready-to-use 10 mM solution in DMSO for in vitro research, with storage and solvent recommendations to support reproducible experiments.
- High purity (99.97%) suitable for biochemical assays.
- Available as a 10 mM solution in DMSO for ready-to-use applications.
- Also supplied as solid in multiple pack sizes (25 mg-500 mg).
- Molecular formula C16H12O3; molecular weight 252.26 g·mol⁻¹.
- Recommended solvent: DMSO; may require sonication to dissolve.
- Storage recommendations: powder -20°C for long term, solution -80°C for extended storage.
TARGETMOL CHEMICALS INC 5 6 7-TRIMETHOXYFLAVONE 25MG
Also available in 1 mL, 1 mg, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 5,6,7-Trimethoxyflavone, a natural product extracted from Japanese Callicarpa, acts as a p38-alpha MAPK inhibitor and exhibits anti-inflammatory properties. Purity 99.11%
Medchemexpress LLC 6-Methoxyflavanone | 3034-04-6 | 254.28 | 1 G
6-Methoxyflavanone (6-MeOF) is a flavonoid compound capable of crossing the blood-brain barrier. It acts as a positive allosteric modulator of GABAA receptors, specifically showing regulatory effects on human recombinant α1β2γ2L and α2β2γ2L GABAA receptors, with low activity on the α1β2 GABAA receptor. Additionally, it inhibits the activation of bitter receptors hTAS2R39 and hTAS2R14, exhibiting a reversible and non-overcome antagonistic effect. This compound is noted for its anti-anxiety, analgesic, and neuropathic pain relief properties.
- Flavonoid compound
- Crosses the blood-brain barrier
- Positive allosteric modulator of GABAA receptors
- Inhibits bitter receptors hTAS2R39 and hTAS2R14
- Exhibits anti-anxiety effects
- Provides analgesia
- Offers relief of neuropathic pain
Medchemexpress LLC 5-methoxyflavone | 42079-78-7 | MFCD00016942 | 100.0% | 252.26 g/mol | C16H12O3 | 100 MG
5-Methoxyflavone is a research-grade flavone (C16H12O3; CAS 42079-78-7) reported to inhibit DNA polymerase-β and exhibit neuroprotective activity. It is supplied as a high-purity solid intended for laboratory research and preparation of DMSO stock solutions.
- High purity (reported 99.97%), suitable for analytical and biological studies.
- Solid, white to off-white powder for convenient handling.
- Soluble in DMSO for preparation of stock solutions.
- Available in multiple pack sizes including 25 mg, 50 mg, 100 mg, and 500 mg.
- Storage: powder stable at -20°C; in solvent store at -80°C for long-term stability.
Cayman Chemical Tangeretin Neurochemicals
A polymethoxylated flavone isolated from citrus peels; inhibits signaling in cancer cells, reducing ERK signaling in T47D breast cancer cells (IC50 ~3 μM)
Selleck Chemical LLC Tangeretin S2363-5mg
Tangeretin (Tangeritin) a natural polymethoxylated flavone concentrated in the peel of citrus fruits an inhibitor of Notch1 is known to have antiproliferative antiinvasive antimetastatic and antioxidant activities
TARGETMOL CHEMICALS INC NOBILETIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Nobiletin (Hexamethoxyflavone) is a natural polymethoxylated flavone isolated from citrus peels with anti-inflammatory and anti-tumor activities. Nobiletin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). purity: 98%
