Flavonoids
TARGETMOL CHEMICALS INC 4-Hydroxyflavone 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 4'-Hydroxyflavone is a flavonoid compound isolated from the roots of Scutellaria baicalensis with anti-inflammatory activity. Purity 99.42%
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | 5 MG
Naringenin chalcone is an orally active intermediate involved in flavonol biosynthesis. It induces apoptosis, inhibits the production of MCP-1 and NO, and exhibits anticancer activity against glioblastoma. It also possesses anti-inflammatory and anti-allergic properties.
- Intermediate in flavonol biosynthesis
- Induces apoptosis
- Inhibits production of MCP-1 and NO
- Exhibits anticancer activity against glioblastoma
- Possesses anti-inflammatory properties
- Possesses anti-allergic properties
Cayman Chemical ApIgenIn 7-glucosIde 50mg
A flavonoid with anti-inflammatory and anxiolytic activities; inhibits LPS-induced nitric oxide production in RAW 264.7 cells from 0.16-10 μM; reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury at 10 mg/kg; increases the number of entries and the time spent in the open arms of the elevated plus maze in rats
Cayman Chemical LuteolIn 7-O-GlucuronIde 1mg
A flavonoid with antioxidant, enzyme inhibitory, and anti-inflammatory properties; scavenges DPPH radicals in a cell-free assay (IC50 = 80.6 μM); inhibits porcine α-amylase and yeast α-glucosidase in vitro (IC50s = 61.5 and 14.7 μM, respectively); inhibits rat aldose reductase in vitro (IC50 = 0.7 μM) and sorbitol accumulation in isolated rat lens at 5 μg/ml; inhibits LPS-induced cytokine release from RAW 264.7 macrophages in a dose-dependent manner
Apexbio Technology LLC AST 487 630124-46-8 5mg
AST487 (CAS 630124-46-8) is a small molecule inhibitor primarily targeting RET kinase exhibiting an IC50 of 0 88 M As a member of the N N -diphenylurea class AST487 inhibits RET autophosphorylation and attenuates downstream signaling pathways such as PLC and ERK in a dose-dependent manner It also displays inhibitory activity against additional kinases including KDR Flt-3 and c-Kit In cellular models harboring RET activating mutations (e g C634W) AST487 suppresses RET-mediated signaling and reduces proliferation of thyroid carcinoma cells with RET mutations In xenograft mouse models oral administration of AST487 leads to a notable reduction in tumor volume making it valuable for preclinical studies of RET-driven cancers
Selleck Chemical LLC 7 8-Dihydroxyflavone
7 8-Dihydroxyflavone (7 8-DHF) acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd 320 nM) the main signaling receptor of brain-derived neurotrophic factor (BDNF)
Medchemexpress LLC AMG 487 (S-enantiomer) | 473720-30-8 | C32H28F3N5O4 | 5 MG
AMG 487 S-enantiomer is the S enantiomer of AMG 487. It functions as an antagonist of the chemokine receptor CXCR3. This product is intended for research use only and is not sold to patients.
- Antagonist of chemokine receptor CXCR3.
- High purity (99.94%).
- Solid appearance.
- Off-white to light yellow color.
- Recommended storage conditions for powder and in solvent.
