Flavonoids
Cayman Chemical Hesperetin Natural Products Ex
A flavonoid with diverse biological activities; reduces ApoB protein levels, ACAT2 expression, and LDL degradation in HepG2 cells from 10-200 µM; inhibits IgG-induced β-hexosaminidase release from RBL-2H3 cells (IC50 = 0.099 mg/ml); inhibits LPS-induced NO production and reduces levels of iNOS, IL-6, and IL-1β in BV-2 microglial cells; inhibits passive cutaneous anaphylaxis in mice at 5 mg/kg; reduces body weight loss, colon shortening, and ulcer severity in a mouse model of TNBS-induced ulcerative colitis; reduces cortical and hippocampal neuronal apoptosis and increases time spent in the target quadrant in the Morris water maze in a mouse model of LPS-induced neuronal inflammation
Medchemexpress LLC Acacetin | 480-44-4 | 284.26 | 50 MG
Acacetin is an orally active flavonoid, 5,7-Dihydroxy-4'-methoxyflavone, isolated from Dendranthema morifolium. It acts as a PI3Kγ inhibitor, inducing cell cycle arrest, apoptosis, and autophagy in various cancer cells. This compound exhibits potent anti-cancer and anti-inflammatory activities, making it a promising candidate for pain-related disease research.
- Orally active flavonoid
- Derived from Dendranthema morifolium
- Docks in ATP binding pocket of PI3Kγ
- Causes cell cycle arrest in cancer cells
- Induces apoptosis and autophagy in cancer cells
- Potent anti-cancer activity
- Potent anti-inflammatory activity
- Potential for pain-related diseases research
- Suppresses microglial activation in neuroinflammation models
- Reduces neuronal cell death in ischemia models
- Decreases visceral and inflammatory nociception
Medchemexpress LLC Hesperidin (Standard) | 520-26-3 | MFCD00006760 | C₂₈H₃₄O₁₅ | 5 MG
Hesperidin (Standard) is the analytical standard of Hesperidin, intended for research and analytical applications. It is a flavanone glycoside isolated from citrus fruits. Hesperidin possesses numerous biological properties, including decreasing inflammatory mediators and exhibiting significant antioxidant, antitumor, and antiallergic activities.
- Analytical standard for hesperidin
- Intended for research and analytical applications
- Flavanone glycoside isolated from citrus fruits
- Decreases inflammatory mediators
- Exhibits significant antioxidant effects
- Exhibits antitumor and antiallergic activities
- Used as a reference standard in qualitative, quantitative and methodological research experiments
- Suitable for HPLC, GC and MS applications
Medchemexpress LLC Hesperidin methylchalcone | 24292-52-2 | 98.0% | 624.59 | 25 G
Hesperidin methylchalcone is an orally active flavonoid with analgesic, anti-inflammatory, and antioxidant properties. It exhibits vasoprotective activity and inhibits oxidative stress, cytokine production, and NF-κB activation. This compound can be utilized for research related to gout disease.
- Orally active flavonoid
- Analgesic properties
- Anti-inflammatory properties
- Antioxidant properties
- Vasoprotective activity
- Inhibits oxidative stress
- Inhibits cytokine production
- Inhibits NF-κB activation
- Can be used for the research of gout disease
Medchemexpress LLC 5,7-Dimethoxyflavone | 21392-57-4 | 50 MG
5,7-Dimethoxyflavone is an analytical standard and a major component of Kaempferia parviflora. It exhibits anti-obesity, anti-inflammatory, and antineoplastic effects. This product is intended for research and analytical applications.
- Inhibits cytochrome P450 (CYP) 3As
- Potent breast cancer resistance protein (BCRP) inhibitor
- Used for qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Shipping is at room temperature in continental US; may vary elsewhere. Store under recommended conditions in the Certificate of Analysis.
Cayman Chemical Hesperetin Natural Products Ex
A flavonoid with diverse biological activities; reduces ApoB protein levels, ACAT2 expression, and LDL degradation in HepG2 cells from 10-200 µM; inhibits IgG-induced β-hexosaminidase release from RBL-2H3 cells (IC50 = 0.099 mg/ml); inhibits LPS-induced NO production and reduces levels of iNOS, IL-6, and IL-1β in BV-2 microglial cells; inhibits passive cutaneous anaphylaxis in mice at 5 mg/kg; reduces body weight loss, colon shortening, and ulcer severity in a mouse model of TNBS-induced ulcerative colitis; reduces cortical and hippocampal neuronal apoptosis and increases time spent in the target quadrant in the Morris water maze in a mouse model of LPS-induced neuronal inflammation
Medchemexpress LLC Hesperetin 7-O-glucoside | 31712-49-9 | 99.4% | 464.42 g/mol | C22H24O11 | 10MG
Hesperetin 7-O-glucoside is a flavanone 7-O-glucoside reported to exhibit anti-inflammatory, antibacterial, and antihypertensive activities. It is used in biochemical and biological research, including enzyme inhibition assays and rodent models of inflammation and metabolic regulation. Supplied as a white to off-white solid with high reported purity, it is intended for research applications.
Sigma Aldrich Fine Chemicals Biosciences Neohesperidin United States Pharmacopeia (USP) Reference Standard | 13241-33-3 | MFCD16661259 | 30MG
Neohesperidin United States Pharmacopeia (USP) Reference Standard | Mol Wt: 610.56 | 13241-33-3 | MFCD16661259 | 30MG
Sigma Aldrich Fine Chemicals Biosciences 3',4'-Dimethoxyflavone | 4143-62-8 | MFCD00143009 | 25MG
3',4'-Dimethoxyflavone | Purity: >=98% (HPLC) | Mol Wt: 282.29 | 4143-62-8 | MFCD00143009 | 25MG
TARGETMOL CHEMICALS INC Acacetin 50MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, exhibiting antinociceptive, anti-inflammatory, and antioxidant activities in different research models. Purity 98%
Medchemexpress LLC 3',4'-dimethoxy-αNF | 14756-24-2 | MFCD00143008 | 98.5% | 332.35 g/mol | C21H16O4 | 1 ML
DiMNF (3',4'-Dimethoxy-αNF) is a small-molecule aryl hydrocarbon receptor (AHR) ligand provided for research use. It is supplied as a 10 mM solution in DMSO (1 mL) and is also available as solid quantities for biochemical and cellular assays.
- Small-molecule AHR modulator for in vitro research.
- Provided as a 10 mM solution in DMSO suitable for cellular assays.
- High purity for reliable experimental results.
- Available in multiple solid sizes for storage or custom use.
- Molecular weight 332.35 g/mol and formula C21H16O4 for reference.
TARGETMOL CHEMICALS INC Neohesperidin 500MG
Also available in 1 g, 5 g, 1 mL, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model. Purity 98.34%
Medchemexpress LLC 3-Methoxyflavone | 7245-02-5 | 99.9% | 252.26 | 1 ML
3-Methoxyflavone is a flavonoid compound isolated from Artemisia incanescens with antiviral activity. It is supplied as a 10 mM solution in 1 mL of DMSO, suitable for research applications.
- Flavonoid compound
- Exhibits antiviral activity
- Purity of 99.9%
- Provided as a 10 mM solution in DMSO
- Recommended storage for solution: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC 6-Methoxyflavone 25mg
6-Methoxyflavone is an orally active methoxyflavone 6-Methoxyflavone suppresses neuroinflammation in microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF- B dependent pathways and the activation of HO-1/NQO-1 signaling 6-Methoxyflavone induces S-phase arrest through the CCNA2/CDK2/p21CIP1 signaling pathway and activates the PERK/EIF2a/ATF4/CHOP pathway in HeLa cells 6-Methoxyflavone acts as a Flumazenil (HY-B0009)-insensitive positive allosteric modulator at human recombinant 1 2 2L and 2 2 2L GABA receptors 6-Methoxyflavone inhibits NFAT Translocation into the nucleus and suppresses T cell activation 6-Methoxyflavone partially restores chronic ethanol-induced behavioral deficits in mice 6-Methoxyflavone antagonizes chronic constriction injury and diabetes associated neuropathic nociception expression 6-Methoxyflavone can be used for the study of cancer inflammation and neurological diseases[1][2][3][4][5][6][7][8]