Linear 1 3-diarylpropanoids
Medchemexpress LLC Cresyl diphenyl phosphate | 26444-49-5 | MFCD00014920 | 97.0% | 340.31 g·mol⁻¹ | C19H17O4P | 100 G
Cresyl diphenyl phosphate is an organophosphate research chemical (CAS 26444-49-5) used in biochemical and developmental biology studies; it disrupts lipid homeostasis in zebrafish embryos. The material is supplied as a colorless to light yellow liquid with a reported purity of 97.0% and a molecular weight of 340.31 g·mol⁻¹.
- Research-grade organophosphate for laboratory studies.
- Disrupts lipid homeostasis in zebrafish embryos, useful for developmental assays.
- High analytical purity suitable for biochemical and assay applications.
- Supplied as a liquid with defined storage recommendations to maintain stability.
- Provided with documented safety and handling guidance for research use only.
Medchemexpress LLC Rac-brassinazole | 224047-41-0 | 5 MG
Rac-brassinazole is a triazole-type inhibitor of brassinosteroid biosynthesis that targets CYP90B and is used in research to modulate BR signaling pathways.
- Triazole-type brassinosteroid biosynthesis inhibitor.
- CAS 224047-41-0.
- Molecular formula C18H18ClN3O.
- Molecular weight 327.81 g/mol.
- Appearance: solid.
- Solubility: DMSO 50 mg/mL; in vivo formulations include DMSO/PEG300/Tween-80/saline and DMSO/corn oil.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | MFCD00016762 | 100 MG
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. It induces apoptosis and inhibits the production of MCP-1 and NO. This compound exhibits anticancer activity against glioblastoma and possesses anti-inflammatory and anti-allergic properties. Intended for research use only.
- Induces apoptosis in glioblastoma cells.
- Inhibits production of MCP-1, TNF-α, and NO in macrophages.
- Increases adiponectin mRNA levels and protein secretion in adipocytes.
- Reduces eosinophilic airway inflammation and airway hyperresponsiveness.
- Suppresses Th2 cytokine production and reduces mucus overproduction.
- Reduces tumor volume and weight in glioblastoma xenograft models.
- Increases plasma adiponectin levels in diabetic mice.
- Inhibits anaphylactic response to IgE-mediated passive cutaneous anaphylaxis.
Medchemexpress LLC 2-propen-1-one, 1,3-diphenyl- | 94-41-7 | 100.0% | 1 ML
Chalcone (2-Propen-1-one, 1,3-diphenyl-) is an α,β-unsaturated ketone used as a synthetic building block and research reagent. It is supplied as a solid or as a prepared 10 mM solution in DMSO, 1 ML, for screening and synthesis applications.
- Offered as solid and as 10 mM solution in DMSO, 1 ML.
- High purity (99.98% by HPLC) suitable for research use.
- Commonly used for synthesis of chalcone derivatives and biological screening.
- Provided with certificate of analysis documenting identity and purity.
Medchemexpress LLC 4-hydroxychalcone | 20426-12-4 | MFCD00016488 | 99.3% | 224.25 g/mol | C15H12O2 | 1 ML
4-Hydroxychalcone is a chalcone metabolite supplied as a 10 mM solution in DMSO for research use. It is reported to inhibit TNF-α-induced NF-κB activation and to exhibit anti-angiogenic and anti-inflammatory effects, providing a high-purity, ready-to-use stock for cell-based and biochemical assays. Handle under recommended storage conditions and protect from light.
- 10 mM solution in DMSO.
- High purity: 99.3%.
- Molecular formula C15H12O2; molecular weight 224.25 g/mol.
- CAS number 20426-12-4.
- Inhibits TNF-α-induced NF-κB pathway; anti-angiogenic and anti-inflammatory activity.
- Store protected from light; in solvent: -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC AKT-IN-6 | 1430056-54-4 | 99.1% | 389.43 | 1 ML
AKT-IN-6 is a potent Akt inhibitor that targets Akt1, Akt2, and Akt3 with IC50s below 500 nM. Akt is a central node in cell signaling, and its aberrant activation is linked to various complex diseases, including type-2 diabetes and cancer.
- Potent Akt inhibitor
- Targets Akt1, Akt2, and Akt3
- Suitable for research applications
Medchemexpress LLC 4'-Hydroxychalcone | 2657-25-2 | 1 ML
4'-Hydroxychalcone is a chalcone isolated from licorice root with hepatoprotective activity. It inhibits TNFa-induced NF-κB activation via proteasome inhibition. It also induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria.
- Isolated from licorice root
- Exhibits hepatoprotective activity
- Inhibits TNFa-induced NF-κB activation through proteasome inhibition
- Induces rapid potassium release from mitochondrial vesicles
- Causes deterioration of respiratory control and oxidative phosphorylation
- Affects cancer cell viability
Medchemexpress LLC Chalcone | 94-41-7 | 100.0% | 50 MG
Chalcone is the parent α,β-unsaturated ketone scaffold used widely as a small-molecule research chemical and synthetic building block. Provided as a high-purity solid, it is used in medicinal chemistry, biochemical assays, and the synthesis of chalcone derivatives. Typical identifiers: CAS 94-41-7; formula C15H12O; molecular weight 208.25 g/mol.
- High purity suitable for research use.
- Useful building block for synthesis of bioactive derivatives.
- Compatible with DMSO; available as solution for screening.
- Supplied with certificate of analysis and safety data for quality and safety.
- Available in small-scale quantities for discovery research.
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | 50 MG
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. It induces apoptosis, inhibits the production of MCP-1 and NO, and exhibits anticancer activity against glioblastoma. It also possesses anti-inflammatory and anti-allergic properties.
- Induces apoptosis
- Inhibits the production of MCP-1 and NO
- Exhibits anticancer activity against glioblastoma
- Has anti-inflammatory and anti-allergic properties
Medchemexpress LLC Pinocembrin chalcone | 4197-97-1 | 1 MG
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound derived from *Helichrysum Trilineatum*. It facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle fatty acid oxidation (FAO), and reduces fat accumulation in the liver and skeletal muscles of high-fat diet-induced (HFD) diabetic mice. It is suitable for research on gastric ulcers and diabetes.
- Antibacterial properties
- Activates AMP-activated protein kinase (AMPK)
- Improves glucose tolerance
- Increases muscle fatty acid oxidation
- Reduces fat accumulation in liver and skeletal muscles
- Supports research on gastric ulcers and diabetes
Medchemexpress LLC Naringenin | 480-41-1 | 99.3% | 272.25 | 5 MG
Naringenin is the predominant flavanone found in Citrus reticulata Blanco. It exhibits strong anti-inflammatory and antioxidant activities, and also possesses anti-dengue virus (DENV) activity.
- Inhibits proliferation and induces apoptosis in HepG2 cells
- Reduces cell viability and increases DNA fragmentation in A431 cells
- Reduces plasma and liver triglyceride and cholesterol levels
- Lowers adiposity and triglyceride content
- Increases hepatic PPARα protein expression and enhances CPT-1 and UCP2 expression
- Boosts hepatic fatty acid oxidation and prevents sterol regulatory element-binding protein 1c-mediated lipogenesis
- Inhibits TNF-α-induced VSMC proliferation and migration
Medchemexpress LLC Pinostrobin chalcone | 18956-15-5 | 99.9% | 270.28 g/mol | C16H14O4 | 10 MG
Pinostrobin chalcone is a naturally occurring chalcone derivative supplied as a high-purity research standard for in vitro biological and analytical studies. It has reported cytotoxic activity against MDA-MB-231 and HT-29 cancer cell lines (IC50 = 20.42 ± 2.23 μg/mL and 22.51 ± 0.42 μg/mL). The compound is provided as a solid and should be stored sealed at 4°C, protected from moisture and light.
- High purity (99.94%).
- Molecular weight 270.28 g/mol.
- Chemical formula C16H14O4.
- CAS number 18956-15-5.
- Suitable for in vitro cytotoxicity and analytical assays.
- Provided in a 10 MG package for laboratory use.
- Store at 4°C, sealed, away from moisture and light.