Linear 1 3-diarylpropanoids
Medchemexpress LLC (R)-(-)-1,2-propanediol | 4254-14-2 | MFCD00066248 | 10g
(R)-(-)-1 2-Propanediol is a (R)-enantiomer of 1 2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes[1]
Medchemexpress LLC Avobenzone | 70356-09-1 | 98.0% | 10 MM 1 ML
Avobenzone is a dibenzoylmethane compound that is widely used as a filter in sunscreens for skin photoprotection in the UVA band. It is also identified as an endocrine disruptor that directly binds to estrogen receptor β and functions as an estrogen agonist.
- Long-Wave UVA Filter.
- Significantly promotes adipogenesis in hBM-MSCs at an EC50 of 14.1 μM.
- Up-regulates mRNA levels of PPARγ during adipogenesis in hBM-MSCs at 10 μM.
- Inhibits proliferative activities of human trophoblast cells and induces apoptosis in HTR8/SVneo cells at concentrations of 1-50 μM over 48 hours.
- Exhibits weak ERα agonism and weak AR antagonism.
Medchemexpress LLC 1,3-Propanedione, 1,3-diphenyl- | 120-46-7 | 98.0% | 224.26 | 1 ML
Dibenzoylmethane is a minor ingredient in licorice that activates Nrf2, playing a role in preventing various cancers and oxidative damage. It acts as an analog of curcumin, causing dissociation from Keap1 and nuclear translocation of Nrf2. It is provided for research use only.
- Activates Nrf2 pathway
- Analog of curcumin
- Prevents cancers and oxidative damage
- Increases HO-1 and Nrf2 protein expression
- Protects against CCl4-induced liver damage in wild-type mice
Apexbio Technology LLC Avobenzone 70356-09-1 10mM (in 1mL DMSO)
Avobenzone (70356-09-1) is a small-molecule agonist targeting estrogen receptor (ER ) It is designed to bind directly to ER thereby modulating endocrine signaling pathways Avobenzone exerts its biological activity primarily through direct receptor binding and estrogenic agonist activity Based on these properties Avobenzone holds research potential in studies investigating endocrine-disrupting chemicals mechanisms of photoprotection UV-induced cellular damage and skin pathology
Medchemexpress LLC Xanthohumol | 6754-58-1 | 354.40 | 1 ML
Xanthohumol is a principal flavonoid derived from hops, acting as an inhibitor of diacylglycerol acyltransferase (DGAT), COX-1, and COX-2. It exhibits anti-cancer and anti-angiogenic properties. Additionally, Xanthohumol demonstrates antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
- Inhibits diacylglycerol acyltransferase (DGAT), COX-1, and COX-2.
- Shows anti-cancer activities.
- Shows anti-angiogenic activities.
- Has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
Medchemexpress LLC Xanthohumol | 6754-58-1 | MFCD00210576 | 354.40 | 500 MG
Xanthohumol is one of the principal flavonoids isolated from hops, known for its inhibitory effects on diacylglycerol acetyltransferase (DGAT), COX-1, and COX-2. It demonstrates anti-cancer, anti-angiogenic, and antiviral activities against various viruses including bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV). This product is intended for research use only.
- Inhibitor of DGAT, COX-1, and COX-2
- Exhibits anti-cancer activity
- Possesses anti-angiogenic activity
- Shows antiviral activity against BVDV, rhinovirus, HSV-1, HSV-2, and CMV
- Appears as a yellow to orange solid
TARGETMOL CHEMICALS INC ISOBAVACHALCONE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei has potent anti-inflammatory activity possible can ameliorate neuronal injury in brain diseases associated with inflammation. purity: 99%
Medchemexpress LLC Xanthohumol (Standard) | 6754-58-1 | 354.40 | 25 MG
Xanthohumol (Standard) | 6754-58-1 | 354.40 | 25 MG
Medchemexpress LLC Xanthohumol D | 274675-25-1 | 370.40 | 5 MG
Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with an IC50 value of 110 μM, and binds to the active site of QR-2. It shows antiproliferative activity on human cancer cell lines in vitro.
- Inhibitor of quinone reductase-2 (QR-2) with an IC50 value of 110 μM
- Binds to the active site of QR-2
- Exhibits antiproliferative activity on human cancer cell lines in vitro
Medchemexpress LLC Phlorizin | 60-81-1 | 99.9% | 436.41 | 5 G
Phlorizin is a non-selective SGLT inhibitor that acts on hSGLT1 and hSGLT2. It also functions as a Na+/K+-ATPase inhibitor.
- Non-selective SGLT inhibitor.
- Inhibits hSGLT1 and hSGLT2.
- Na+/K+-ATPase inhibitor.
- Decreases blood glucose levels.
- Prevents nerve fiber decrease and retinal abnormalities.
Selleck Chemical LLC Phloretin (RJC 02792) S2342-10mM/1mL
Phloretin (RJC 02792 NSC 407292 Dihydronaringenin) is a dihydrochalcone found in apple tree leaves which shows beneficial effects on diabetes
Sigma Aldrich Fine Chemicals Biosciences Phloretin >=99% | 60-82-2 | MFCD00002288 | 250MG
Phloretin >=99% | Purity: >=99% | Mol Wt: 274.27 | 60-82-2 | MFCD00002288 | 250MG
