Oxytetracycline hydrochloride is an antibiotic that belongs to the tetracycline class. It is a potent inhibitor of both Gram-negative and Gram-positive bacteria. This compound acts as a protein synthesis inhibitor by preventing the binding of aminoacyl-tRNA to the m-ribosomal RNA complex. Additionally, Oxytetracycline hydrochloride exhibits anti-HSV-1 activity. Oxytetracycline is a bacterial aromatic polyketide, synthesized by a type II polyketide synthase which generates its poly-beta-ketone backbone through successive decarboxylative condensation of malonyl-CoA extender units, followed by modifications from cyclases, oxygenases, transferases, and other tailoring enzymes.
- Antibiotic belonging to the tetracycline class
- Potent inhibitor of Gram-negative and Gram-positive bacteria
- Functions as a protein synthesis inhibitor
- Prevents aminoacyl-tRNA binding to the m-ribosomal RNA complex
- Possesses anti-HSV-1 activity