Phenols
Medchemexpress LLC Dolutegravir intermediate-1 | 1335210-23-5 | MFCD28978322 | 99.8% | 315.28 g/mol | C13H17NO8 | 100 G
Dolutegravir intermediate-1 is a synthetic building block used in the synthesis of the HIV integrase inhibitor dolutegravir. It is supplied as a high-purity solid or as a ready-to-use solution for research and development applications, with documentation available for safe handling and quality verification.
- High purity (99.8%) for reliable synthetic performance.
- Available as solid and as 10 mM solution in DMSO for flexible use.
- Multiple package sizes up to 500 g to support scale-up.
- Documented safety and quality data including SDS and COA.
- Suitable for research and process development workflows.
Chem-Impex International, Inc. 3,4-Dihydroxybenzoic acid | 99-50-3 | MFCD00002509 | 25G
3,4-Dihydroxybenzoic acid, 99-50-3, MFCD00002509, 25G
Apexbio Technology LLC Rolapitant HCl 552292-08-7 (free base) 1mg
Rolapitant HCl is a small-molecule antagonist targeting the neurokinin NK1 receptor It is designed to block NK1 receptor signaling pathways thereby reducing receptor activation mediated by substance P Rolapitant HCl exerts its biological activity primarily through competitive antagonism of the NK1 receptor In preclinical models including gerbils and ferrets rolapitant suppressed both acute and delayed emetic responses induced by NK1 receptor agonists Based on these pharmacological properties rolapitant HCl holds research potential in the management of postoperative nausea and vomiting
Medchemexpress LLC PF-00356231 hydrochloride | 820223-77-6 | 99.0% | 464.96 | 50 MG
PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12. It binds to MMP-12, forming a complex and shows potency against MMP-13, MMP-8, MMP-9, and MMP-3. Its activity can be significantly influenced by the presence of acetohydroxamate (AH).
- Specific, non-peptidic, non-zinc chelating ligand
- Inhibitor of matrix metalloproteinase MMP-12
- Potent against MMP-13, MMP-8, MMP-9, and MMP-3
- Activity affected by acetohydroxamate (AH)
Medchemexpress LLC Rs 67333 hydrochloride | 168986-60-5 | 99.7% | 389.36 | C19H30Cl2N2O2 | 100 MG
RS 67333 hydrochloride is a research-grade 5-HT4 (serotonin 4) receptor partial agonist supplied as the hydrochloride salt for use in neuroscience and pharmacology studies. It is commonly used to probe 5-HT4 receptor function in vitro and in vivo, with reported neuroprotective and pro-cognitive activity.
- Partial agonist at 5-HT4 receptors, useful for receptor pharmacology studies.
- Hydrochloride salt form for improved solubility in aqueous media.
- High purity (99.68%) suitable for research applications.
- Characterized by CAS 168986-60-5 and defined molecular properties for formulation.
- Available in small research quantities (e.g., 100 MG) for in vitro and in vivo use.
- Relevant for studies of cognition, neuroprotection, and serotonergic signaling.
Apexbio Technology LLC Dicyclomine HCl 67-92-5 5g
Dicyclomine Hydrochloride (CAS 67-92-5) is an orally active muscarinic acetylcholine receptor antagonist that primarily interacts with the M1 and M2 receptor subtypes It exhibits high binding affinity for the M1 subtype (Ki 5 nM) and moderate affinity for M2 receptors (Ki 55 nM) By inhibiting these receptors Dicyclomine HCl is utilized in studies investigating muscarinic receptor-mediated signal transduction Additionally it is commonly employed in pharmacological and pathophysiological research involving gastrointestinal smooth muscle spasm and related mechanisms
Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | 99.99% | C31H45ClN2O5S | 100 MG
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+, and Ca2+ currents. It serves as a multichannel blocker for atrial fibrillation, making it suitable for various research applications.
- Inhibits Na+, K+, and Ca2+ currents.
- Potently blocks acetylcholine-activated K+ current.
- Blocks IKr and ICa-L with specific IC50 values.
- Exhibits state-dependent inhibition of fast Na+ channel current.
- Significantly reduces incidence of ventricular fibrillation in vivo.
- Inhibits carotid artery thrombus formation in vivo.
Medchemexpress LLC 1-Bromo-3,5-bis(trifluoromethyl)benzene | 328-70-1 | 99.94% | C8H3BrF6 | 1 KG
1-Bromo-3,5-bis(trifluoromethyl)benzene is a biochemical reagent suitable for use as a biological material or organic compound in life science research. It is also utilized in the preparation of the tetrakis[3,5-bis(trifluoromethyl)phenyl]borate ion.
- Functions as a stabilizing counterion for electrophilic organic and organometallic cations
- Suitable for life science related research
- Can be used as a biological material or organic compound
Apexbio Technology LLC Rabeprazole sodium 117976-90-6 10mM (in 1mL DMSO)
Rabeprazole sodium (CAS 117976-90-6) is a small-molecule inhibitor targeting gastric H /K -ATPase It is designed to irreversibly inhibit this proton pump enzyme thereby suppressing gastric acid secretion Rabeprazole sodium exerts its biological activity primarily through irreversible inhibition of H /K -ATPase It also induces apoptosis and inhibits uridine nucleoside hydrolase (UNH) with an IC50 value of 0 3 M Based on these pharmacological properties Rabeprazole sodium holds research potential in studies of gastric ulcer gastroesophageal reflux disease and the investigation of proton pump inhibition apoptosis induction and nucleoside metabolism regulation