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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Oteseconazole (VT-1161) is an orally active anti-fungal agent. Oteseconazole displays no obvious effect on human CYP51. It also potently binds to and inhibits Candida albicans CYP51 (Kd <39 nM). purity: 99%
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The M-CSF protein regulates hematopoietic precursor cells promoting their survival proliferation and differentiation M-CSF Protein Cynomolgus/Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque cynomolgus-derived M-CSF protein expressed by HEK293 with C-hFc labeled tag
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Recombinant human macrophage colony-stimulating factor (M-CSF, CSF-1) is supplied as a lyophilized, tag-free protein for in vitro research. It promotes proliferation and differentiation of mononuclear phagocyte lineage cells and is provided with confirmed purity and specific biological activity for cell-based assays and biochemical studies.
Homodimeric hematopoietic growth factor that stimulates mononuclear phagocyte proliferation.
Lyophilized, tag-free recombinant protein for flexible reconstitution.
Expressed in E. coli to provide consistent material for assays.
Greater than 95% purity as determined by reducing SDS-PAGE.
High biological potency with ED50 in the low ng/mL range in M-NFS-60 proliferation assay.
Available in small research sizes suitable for pilot studies and optimization.
Stable when stored at -20°C; aliquot and freeze after reconstitution for long-term storage.
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Complement C3/C3a protein activates the complement system playing a central role in both classical and alternative pathways C3b binds covalently to cell surface carbohydrates or immune aggregates while C3a acts as an inflammatory mediator inducing neutrophil chemoattraction and promoting smooth muscle contraction increased vascular permeability and histamine release The shorter isoform of C3a stimulates B-cells Complement C3/C3a Protein Mouse is the recombinant mouse-derived Complement C3/C3a protein expressed by E coli with tag free
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h/m CD36-sh-Puro shRNA lentiviral vector expressing with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m CD36 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse CD36 molecule (CD36) The shRNA has been validated to meet or exceed 70% CD36 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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h/m ACSL4-sh-GFP/Luc shRNA lentiviral vector expressing GFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m ACSL4 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse acyl-CoA synthetase long chain family member 4 (ACSL4) The shRNA has been validated to meet or exceed 70% knockdown of ACSL4 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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Also available in 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed. purity: 99%
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h/m FASN-sh-GFP-Puro shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m FASN shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fatty acid synthase (FASN) The shRNA has been validated to meet or exceed 70% FASN knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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Recombinant mouse interleukin-13 (IL-13) is expressed in E. coli and supplied as a His-tagged, animal-free lyophilized powder for research use. It is intended for cell-based assays and bioactivity testing, with documented activity in TF-1 cell proliferation assays.
His-tagged protein for detection and purification.
Animal-free production suitable for cell culture applications.
Lyophilized powder; recommended reconstitution to 100-200 μg/mL in ddH2O.
Approximate molecular weight ~11 kDa as determined by SDS-PAGE.
High specific activity (>2.5x10^5 IU/mg); ED50 <10 ng/mL in TF-1 assay.
Store at -20°C for long-term storage; add carrier protein for stability after reconstitution.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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