Phenols
Medchemexpress LLC GM-CSF 500ug
GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2 GM-CSF R alpha binds to the cytokine with high specificity and low affinity[1] GM-CSF R alpha binds to GM-CSF and induces cell differentiation[2] GM-CSF R alpha monoclonal antibody decreases GM-CSFR expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA)[3] GM-CSF R alpha Protein Human (HEK293 Fc) is a recombinant protein with a C-Terminal Fc label It consists of 320 amino acids (M1-G320) and is produced in HEK293 cells
Medchemexpress LLC 3-Bromo-5-chloropyridine | 73583-39-8 | 192.44 | 10 G
3-Bromo-5-chloropyridine is a widely used heterocyclic compound. It can be utilized in the synthesis of various compounds and serves as an intermediate in the production of crop protectants for the agricultural chemicals industry. This compound also participates in cross-coupling reactions. It appears as an off-white to light brown solid.
- Can be used to synthesize various compounds.
- Serves as an intermediate in crop protectant production.
- Participates in cross-coupling reactions.
- Appears as an off-white to light brown solid.
- For research use only.
Medchemexpress LLC SR9011 hydrochloride | 2070014-94-5 | 99.0% | 515.50 | 1 ML
SR9011 hydrochloride is a REV-ERBα/β agonist with IC50s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ, respectively. This compound offers several key features and benefits:
- Acts as a REV-ERBα/β agonist
- Suppresses the expression of BMAL1 mRNA in HepG2 cells in a REV-ERBα/β-dependent manner
- Suppresses proliferation of breast cancer cell lines
- Appears to pause the cell cycle of breast cancer cells prior to M phase
- Causes an increase in cells in the G0/G1 phase and a decrease of cells in S and G2/M phase
- Displays reasonable plasma exposure in vivo
- Suppresses plasminogen activator inhibitor type 1 gene (Serpine1), cholesterol 7α-hydroxylase (Cyp7a1), and sterol response element binding protein (Srepf1) in a dose-dependent manner in mice
- Administration to mice results in loss of locomotor activity during the subject dark phase
Accela Chembio Inc 5-bromo-2-fluorophenol | 100g | 112204-58-7 | MFCD07782066 | 98% | Shelf Life: 1620 Days | Light Sensitive
5-bromo-2-fluorophenol | 100g | 112204-58-7 | MFCD07782066 | 98% | Shelf Life: 1620 Days | Light Sensitive
Medchemexpress LLC Thianthrene | 92-85-3 | MFCD00005065 | 100.0% | 216.32 g/mol | C12H8S2 | 25 G
Thianthrene (CAS 92-85-3) is a sulfur-containing tricyclic research chemical used in biochemical assays and reported as an inhibitor of Leishmania donovani pteridine reductase 1 (PTR1). It is supplied for research and analytical applications with high reported purity and is available in solution and solid forms to support various laboratory workflows.
- High purity suitable for biochemical research.
- Reported PTR1 inhibitory activity for parasite biology studies.
- Available as DMSO solution and solid quantities for experimental flexibility.
- Intended for research and analytical applications only.
- Provided with a safety data sheet and handling documentation.
Medchemexpress LLC Abametapir | 1762-34-1 | 184.24 | 25 G
Abametapir is a metalloproteinase (MMP) inhibitor that targets metalloproteinases crucial for egg hatching and louse development. It can inhibit the hatching of both head and body lice. Abametapir is also capable of chelating heavy metal ions such as iron, copper, and zinc, allowing it to interact with various insect targets that require metal co-factors for their function, including metalloproteinases.
- Inhibits metalloproteinases critical for egg hatching and louse development.
- Effective against both head and body lice.
- Chelates heavy metal ions like iron, copper, and zinc.
- Interacts with insect targets requiring metal co-factors.
Medchemexpress LLC o,p'-DDE (2,4'-dichlorodiphenyldichloroethylene) | 3424-82-6 | 25 MG
o,p'-DDE (2,4'-DDE) is an organochlorine pesticide metabolite and degradation product of DDT supplied as an analytical reference standard for environmental and toxicology research. It is provided in small vial quantities suitable for laboratory analytical workflows.
- Used as an analytical standard for environmental and toxicology analysis.
- Metabolite and degradation product of DDT.
- Chemical formula C14H8Cl4.
- Molecular weight 318.03 g/mol.
- Available in small vial sizes including 25 mg for lab-scale analyses.
- Refer to the product datasheet for exact purity and handling instructions.
Medchemexpress LLC Glurate (4-Acetylbutyric acid) | 3128-06-1 | MFCD00004412 | 130.14 | 25 G
Glurate (4-Acetylbutyric acid) is an acylating agent. It plays a role in the development of antiviral compounds, specifically those targeting retroviruses such as herpes virus and HIV. It is also involved in the synthesis of acyclic nucleoside derivatives and 5-hydroxyhexanoic acid.
- Acylating agent
- Used in the development of antiviral compounds targeting retroviruses (herpes virus, HIV)
- Utilized in the synthesis of acyclic nucleoside derivatives
- Utilized in the synthesis of 5-hydroxyhexanoic acid
Apexbio Technology LLC 3-Hydroxyphenylacetic acid 621-37-4 5g
3-Hydroxyphenylacetic acid (CAS 621-37-4) is an endogenous aromatic organic acid and a secondary intermediate in the metabolic pathways of tyrosine and phenylalanine Evidence suggests that it participates in modulating interactions between the gut microbiota and host metabolic processes and may impact neurotransmitter homeostasis Due to its involvement in these biochemical pathways 3-hydroxyphenylacetic acid is frequently employed as a metabolic biomarker to assess gut microbial activity and to investigate the pathophysiological mechanisms underlying neuro-metabolic disorders