Phenols
Medchemexpress LLC (R)-(+)-tert-Butylsulfinamide | 196929-78-9 | 100.0% | 121.20 | 25 G
(R)-(+)-tert-Butylsulfinamide is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. It achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, which can then be removed under acidic conditions to obtain the target product.
- Chiral reagent for asymmetric synthesis.
- Used in the synthesis of amines, amino acids, and amino alcohols.
- Achieves stereoselective reactions.
- Participates in cycloaddition and cyclization reactions of enynes and diynes through asymmetric induction, N-alkylation, and deprotection or oxidation under mild conditions to construct polycyclic scaffold libraries related to alkaloid and terpenoid natural products.
Medchemexpress LLC N,N'-Dibenzylethylenediamine | 140-28-3 | 99.8% | 240.34 | 100 G
N,N'-Dibenzylethylenediamine is a biochemical assay reagent that forms chelators with metals and interacts with penicillin to create a stable and tasteless salt of penicillin. It is intended for research use only.
- Forms chelators with metals
- Interacts with penicillin to form a stable and tasteless salt
- Appears as solid below 26°C, liquid above 26°C
- Ranges from colorless to light yellow
- Store at 4°C, protected from light
- Soluble in DMSO for in vitro use (200 mg/mL)
- Protocols available for in vivo dissolution in various mixtures
![Medchemexpress LLC DBU (1,8-Diazabicyclo[5.4.0]undec-7-ene) | 6674-22-2 | 99.8% | 152.24 | 500 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000400987-logo.png-250.jpg){kind=logo}
Medchemexpress LLC DBU (1,8-Diazabicyclo[5.4.0]undec-7-ene) | 6674-22-2 | 99.8% | 152.24 | 500 G
DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) is a bicyclic, sterically hindered amidine with strong basicity, possessing multiple properties such as nucleophilicity and coordination ability. It is prone to hydrolysis and can undergo addition, substitution, cyclization, and other reactions with various substrates to form derivatives containing its scaffold. DBU can also be used as a catalyst.
- Strong basicity
- Possesses nucleophilicity and coordination ability
- Prone to hydrolysis
- Can undergo addition, substitution, and cyclization reactions
- Can be used as a catalyst
- Derivatives may exhibit fluorescence and anticancer properties
Medchemexpress LLC Monobenzone | 103-16-2 | MFCD10687031 | 99.9% | 200.24 | 100 G
Monobenzone is a potent skin depigmenting agent with potential for vitiligo research. It also acts as an inhibitor of RNR enzyme activity, targeting the RRM2 protein. This demonstrates significant anti-leukemia efficacy both in vitro and in vivo, by inhibiting acute myeloid leukemia (AML) cell proliferation and DNA synthesis, and inducing cell cycle arrest and apoptosis.
- Inhibits AML cell proliferation and DNA synthesis.
- Induces cell cycle arrest and apoptosis in various AML cell lines.
- Blocks DNA damage repair.
- Can overcome drug resistance in certain cell lines.
- Synergistically inhibits cell growth with Bcl-2 inhibitor.
- Induces skin depigmentation in mice.
- Effectively inhibits AML cell xenograft growth in nude mice with low toxicity.
![Medchemexpress LLC Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl] | 1664335-55-0 | 99.0% | 419.44 g/mol | C25H22FNO4 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000307969.png-250.jpg)
Medchemexpress LLC Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl] | 1664335-55-0 | 99.0% | 419.44 g/mol | C25H22FNO4 | 1 ML
TAK-615 is a small-molecule negative allosteric modulator of the lysophosphatidic acid receptor 1 (LPA1), supplied as a 10 mM solution in 1 mL for research use. It is commonly used in studies of pulmonary fibrosis and LPA1-mediated signaling. CAS 1664335-55-0; molecular weight 419.44 g/mol.
- Negative allosteric modulator of the LPA1 receptor for receptor pharmacology studies.
- Supplied as a 10 mM solution in 1 mL for ready-to-use in vitro experiments.
- High purity (98.97%) suitable for research applications.
- Chemical formula C25H22FNO4 and molecular weight 419.44 g/mol.
- Provided with certificate of analysis for batch-specific quality data.
Medchemexpress LLC Nvp-bsk805 dihydrochloride | 1942919-79-0 | 99.4% | 563.47 | 1 ML
NVP-BSK805 dihydrochloride is a potent, ATP-competitive JAK2 inhibitor. It targets JAK2 JH1, wild-type JAK2, and FL JAK2 V617F activity, effectively suppressing the growth of JAK2V617F-bearing acute myeloid leukemia cell lines and blocking STAT5 phosphorylation. It also enhances the efficacy of vincristine treatment in drug-resistant cancer cells.
- ATP-competitive inhibitor.
- Highly potent and selective JAK2 inhibitor.
- Inhibits full-length wild-type JAK2 and FL JAK2 V617F activity.
- Suppresses the growth of JAK2V617F-bearing acute myeloid leukemia cell lines.
- Blocks STAT5 phosphorylation.
- Shows bias for JAK2 over JAK1 and JAK3 inhibition.
- Improves P-gp inhibitory activity.
- Increases sensitization of drug-resistant cancer cells to vincristine treatment.
Medchemexpress LLC PTCDA | 128-69-8 | ≥98.0% | 392.32 | 100 G
PTCDA is an organic dye molecule and an organic semiconductor. It is for research use only and not sold to patients.
- Organic dye molecule
- Organic semiconductor
Apexbio Technology LLC Ozagrel HCl 78712-43-3 10mM (in 1mL DMSO)
Ozagrel hydrochloride (CAS 78712-43-3) is a small molecule inhibitor of thromboxane A2 (TXA2) synthase modulating platelet activity by suppressing TXA2 production In experimental models Ozagrel hydrochloride selectively inhibits TXA2-mediated human platelet aggregation exhibiting an IC50 of approximately 53 12 M This compound is employed in platelet-related assays to investigate the role of TXA2 signaling in coagulation thrombosis and cardiovascular pathophysiology
eMolecules Ambeed / 2-Bromo-5-iodobenzaldehyde / 250mg / 490535830 / A215119 / / 1032231-24-5 / MFCD07779027 / 310.916 / C7H4BrIO
Ambeed / 2-Bromo-5-iodobenzaldehyde / 250mg / 490535830 / A215119 / / 1032231-24-5 / MFCD07779027 / 310.916 / C7H4BrIO
Apexbio Technology LLC HOSu 6066-82-6 250g
HOSu (N-hydroxysuccinimide) is a reactive ester reagent widely utilized in biochemical and biomedical research Chemically it functions by activating carboxyl groups to form a transient ester intermediate allowing subsequent formation of amide bonds through nucleophilic substitution between the ester intermediate and suitable amino-containing biomolecules This reaction mechanism provides a straightforward approach for controlled conjugation of proteins peptides or other amine-bearing molecules Typical research applications include protein labeling peptide conjugation functionalization of biosensor surfaces and bioconjugation of biomolecules onto nanoparticle carriers or biomaterials
Medchemexpress LLC 2-Butene-1,4-diamine, N1, N4-bis[3-(ethylamino)propyl]-, hydrochloride (1:4), (2Z)- | 206991-64-2 | 95.0% | 402.27 | 5 MG
PG-11047 (CGC-11047) is a polyamine analogue primarily used for breast cancer research. It effectively inhibits the growth of breast cancer cell lines and significantly reduces the S phase fraction at doses that induce minimal apoptosis. At higher concentrations, PG-11047 is shown to induce apoptosis.
- Used in breast cancer research
- Reduces the S-phase fraction of cells
- Induces and analyzes apoptosis at high concentrations
![Medchemexpress LLC 6-isopropyl-7-oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile | 1628208-23-0 | 98.2% | 278.31 | C16H14N4O | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000214794.png-250.jpg)
Medchemexpress LLC 6-isopropyl-7-oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile | 1628208-23-0 | 98.2% | 278.31 | C16H14N4O | 100 MG
CPI-455 is a selective, cell-active inhibitor of the KDM5 (lysine demethylase 5) family. It increases global H3K4 trimethylation, shows potent biochemical inhibition of KDM5A (reported IC50 ≈ 10 nM), and reduces the number of drug-tolerant persister cancer cells in cell-based models. CPI-455 is used as a research tool to probe KDM5 biology and epigenetic regulation in cancer and other systems.
- Potent enzyme inhibition with reported low-nanomolar activity.
- Cell-active modulation of histone H3K4 trimethylation.
- Useful for studying drug-tolerant persister phenotypes in cancer models.
- High reported purity suitable for biochemical and cellular assays.
- Stable powdered compound for standard cold storage and handling.
Medchemexpress LLC (S)-(-)-tert-Butylsulfinamide | 343338-28-3 | 99.9% | 121.20 | 25 G
(S)-(-)-tert-Butylsulfinamide is a compound featuring a chiral sulfur atom. It is utilized in the synthesis of other compounds and serves as a chiral auxiliary in the asymmetric synthesis of organic compounds.
- Contains a chiral sulfur atom
- Used in the synthesis of other compounds
- Acts as a chiral auxiliary in asymmetric synthesis of organic compounds
Kyfora Bio Smashgene Transfection Reagent 1mL bottle transfection reagent 1/EA
SmashGene is a next-generation transfection reagent engineered to simplify workflows while delivering stronger performance and smarter economics. Designed to eliminate the need for enhancers, it enables a more streamlined and cost-effective transfection process without sacrificing yield. By reducing complexity and minimizing variables, SmashGene accelerates development timelines and improves reproducibility from early research through scale-up. It consistently produces higher titers than leading competitor reagents while requiring fewer components, resulting in lower overall production costs through reduced bioreactor runs and simplified downstream processing. Compatible with both adherent and suspension cell systems across a wide range of media conditions, SmashGene offers exceptional flexibility for diverse process strategies. Fully synthetic and manufactured in the USA, it ensures reliable supply, consistent quality, and greater control from flask to bioreactor.