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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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2-Bromo-2'-methoxyacetophenone is an irreversible inhibitor for MurA, inhibiting MurA in *E. coli* with an IC50 of 0.38 μM. It can be used in antibacterial research for blocking bacterial cell wall synthesis.
Inhibits MurA in *E. coli* with an IC50 of 0.38 μM.
Used in antibacterial research.
Blocks bacterial cell wall synthesis.
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GRP75-IN-1 dihydrochloride is an anti-endometrial cancer (EC) agent that induces apoptosis. It reduces Ca2+ levels in mitochondria by targeting GRP75 and disrupting its interaction with IP3R.
Induces apoptosis in endometrial cancer cells
Reduces mitochondrial Ca2+ levels
Targets GRP75 and disrupts its interaction with IP3R
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KRAS G12C inhibitor 15 is a small-molecule covalent inhibitor selective for the KRAS G12C mutant, reported in patent WO2019110751A1 (compound 22). The compound shows potent biochemical activity (IC50 = 5 nM) and is supplied for research use as a high-purity solid or as a ready-to-use DMSO solution.
Potent KRAS G12C inhibitor with IC50 = 5 nM.
Molecular formula C25H21ClF2N4O3 and molecular weight 498.91 g/mol.
Purity 98.5% (HPLC).
Available as mg-scale powder (1-100 mg); larger quantities available by quote.
Offered as 10 mM solution in DMSO, 1 mL, ready for use.
Product data sheet and safety data sheet available for download.
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Fasudil hydrochloride is the hydrochloride salt of fasudil, a nonspecific RhoA/ROCK inhibitor used in research to investigate Rho-kinase-mediated signaling and kinase activity. It has CAS 105628-07-7, molecular formula C14H18ClN3O2S, and a molecular weight of 327.83 g/mol. The compound is supplied as a high-purity research reagent and is soluble in water and DMSO at the concentrations indicated on the product datasheet.
Nonspecific RhoA/ROCK inhibitor for biochemical and cellular studies.
Hydrochloride salt form for improved aqueous solubility.
High purity (99.97%) suitable for research applications.
Molecular weight 327.83 g/mol; formula C14H18ClN3O2S.
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L-Thioproline is a proline derivative. Amino acids and amino acid derivatives are commercially used as ergogenic supplements. They can influence the secretion of anabolic hormones, provide fuel during exercise, improve mental performance during stress-related tasks, and help prevent exercise-induced muscle damage. These compounds are recognized as beneficial ergogenic dietary substances.
Proline derivative
Influences anabolic hormone secretion
Provides fuel during exercise
Improves mental performance during stress
Helps prevent exercise-induced muscle damage
Beneficial ergogenic dietary substance
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E-Selectin/CD62E protein a cell-surface glycoprotein mediates the adhesion of blood neutrophils to cytokine-activated endothelium through interaction with SELPLG/PSGL1 It also potentially contributes to capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 These multifaceted interactions highlight E-Selectin s role in cell adhesion and its potential influence on vascular development E-Selectin/CD62E Protein Mouse (HEK293 His) is the recombinant mouse-derived E-Selectin/CD62E protein expressed by HEK293 with C-His C-10 His labeled tag
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MIP-3 beta/CCL19 Protein Mouse is a CC chemokine that is strongly chemotactic for CD4 T cells and CD8 T cells and acts as a ligand that binds specifically to the chemokine receptor CCR7 to mediate tissue immunity inflammatory responses and antiviral infections MIP-3 beta/CCL19 Protein Mouse is a recombinant mouse MIP-3 beta/CCL19 (G26-S108) protein expressed by E coli[1][2]
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