Phenols
Apexbio Technology LLC TC-H 106 937039-45-7 10mg
TC-H 106 (CAS 937039-45-7) is a selective inhibitor of class I histone deacetylases (HDACs) targeting HDAC1 HDAC2 HDAC3 and HDAC8 with reported IC50 values of 150 nM 760 nM 370 nM and 5000 nM respectively By inhibiting HDAC activity TC-H 106 interferes with the removal of acetyl groups from histone lysine residues thereby modulating chromatin structure and gene expression In cellular assays TC-H 106 increases histone H3 acetylation in lymphoblastoid cells derived from Friedreich s ataxia (FRDA) patients and enhances frataxin mRNA levels in FRDA mouse models These findings highlight its application in studying epigenetic mechanisms and therapeutic approaches related to HDAC inhibition particularly in neurodegenerative disease models
Apexbio Technology LLC HyperScript™ III First-Strand cDNA Synthesis Kit 50rxn
HyperScript III First-Strand cDNA Synthesis Kit is an enzymatic reagent kit designed for generating first-strand complementary DNA (cDNA) from total RNA or poly(A) RNA templates It utilizes HyperScript III Reverse Transcriptase an engineered derivative of M-MLV reverse transcriptase with reduced RNase H activity and enhanced thermostability and fidelity HyperScript III First-Strand cDNA Synthesis Kit enables efficient synthesis of cDNA with extended length superior efficiency on GC-rich templates and compatibility with various primer types including random primers Oligo(dT) V/N and gene-specific primers Based on these features HyperScript III First-Strand cDNA Synthesis Kit is applicable for downstream applications such as PCR qPCR and gene expression analyses
eMolecules 63286-28-2 | 2-Chloro-3-hydrazinopyrazine | Oakwood Chemicals | MFCD08272804 | 144.560 | C4H5ClN4 | 95.000 | NNc1nccnc1Cl | 100g | 480135391
2-Chloro-3-hydrazinopyrazine | Oakwood Chemicals | 63286-28-2 | MFCD08272804 | 144.560 | C4H5ClN4 | 95.000 | NNc1nccnc1Cl | 100g | 480135391
Medchemexpress LLC HY-108593 10mg Medchemexpress, BMS-191011 CAS:202821-81-6 Purity:>98%
Medchemexpress, HY-108593 10mg BMS-191011 CAS:202821-81-6 BMS-191011 (BMS-A) is an opener of the large-conductance, Ca2++-activated potassium (maxi-K) channel, effective in stroke models. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Ro 106-9920 62645-28-7 10mg
Ro 106-9920 (CAS 62645-28-7) is a small molecule inhibitor that selectively suppresses the activation of the NF-kappaB signaling pathway By interfering with NF-kappaB function Ro 106-9920 modulates transcriptional events involved in cellular inflammatory responses survival and tumor progression Aberrant NF-kappaB activity is frequently observed in various cancer cell types and is linked to enhanced proliferation invasion and resistance to apoptosis Ro 106-9920 is widely utilized in cellular and animal studies to investigate the roles of NF-kappaB in oncogenesis and related pathologies providing a valuable tool for elucidating NF-kappaB-mediated mechanisms and evaluating potential therapeutic strategies
eMolecules 1207609-52-6 | Ambeed | 6-Chloro-3-fluoropicolinonitrile | 100mg | 596329814 | A273736 | MFCD18250470 | 156.54 | C6H2ClFN2
Ambeed | tert-Butyl (4-methoxy-2-methylphenyl)carbamate | 100mg | 600842801 | A546043 | 129822-42-0 | MFCD11045029 | 237.299 | C13H19NO3
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Cambridge Isotope Laboratories 2 4-Dichlorophenol (ring-D3 98%) 0 5 g
2 4-Dichlorophenol (ring-D3 98%) 0 5 g
eMolecules 1181226-02-7 | Medchem Express | ZL006 | 5mg | 446255507 | HY-100456 | MFCD20527326 | 328.15 | C14H11Cl2NO4
Medchem Express | SGI-7079 | 5mg | 446262121 | HY-12964 | 1239875-86-5 | MFCD28963942 | 455.541 | C26H26FN7
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eMolecules 63286-28-2 | 2-Chloro-3-hydrazinylpyrazine | Combi-Blocks, Inc. | MFCD08272804 | 144.560 | C4H5ClN4 | 97.000 | NNc1nccnc1Cl | 100g | 586074687
2-Chloro-3-hydrazinylpyrazine | Combi-Blocks, Inc. | 63286-28-2 | MFCD08272804 | 144.560 | C4H5ClN4 | 97.000 | NNc1nccnc1Cl | 100g | 586074687
![Medchemexpress LLC 1-(5-chloro-2-hydroxyphenyl)-3-[2-chloro-5-(trifluoromethyl)phenyl]urea | 501684-93-1 | 8ge98.0% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000230392.png-250.jpg)
Medchemexpress LLC 1-(5-chloro-2-hydroxyphenyl)-3-[2-chloro-5-(trifluoromethyl)phenyl]urea | 501684-93-1 | 8ge98.0% | 25 MG
NS 1738 is a research chemical that acts as a positive allosteric modulator of the α7 nicotinic acetylcholine receptor (α7 nAChR). It potentiates α7 nAChR activity (EC50 = 3.4 μM in oocyte assays) and is provided for laboratory research use only; not for human or clinical use.
- Positive allosteric modulator of α7 nAChR (EC50 = 3.4 μM in oocyte assays).
- Reported molecular weight 365.13 g·mol⁻1 and formula C14H9Cl2F3N2O2.
- CAS registry number 501684-93-1 for substance identification.
- Typically supplied in small research quantities (e.g., 25 MG) for in vitro studies.
- Intended for laboratory research use only; not for human use.
Medchemexpress LLC 2-Chloro-3-pyridinol | 6636-78-8 | 99.9% | 129.55 | 100 G
2-Chloro-3-pyridinol is a biochemical reagent useful in life science research and for synthesizing active compounds. It is also found as a halopyridinol disinfection by-product in drinking water samples.
- Can be used as a biological material or organic compound
- Suitable for life science related research
- Can be used in the synthesis of other active compounds
- Low cytotoxicity to human hepatocellular carcinoma HepG2 cells