Phenols
Medchemexpress LLC Ifebemtinib (hydrochloride) | 1227948-82-4 | 99.2% | 625.01 | 10 MM/1 ML
Ifebemtinib is an orally bioavailable inhibitor of the non-receptor, cytoplasmic tyrosine kinase protein tyrosine kinase 2 (FAK: PTK2) with potential antineoplastic activity. It targets and inhibits PTK2 in an adenosine triphosphate (ATP)-competitive manner, preventing PTK2-mediated downstream signaling and inhibiting migration, proliferation, invasion, and survival in PTK2-overexpressing tumor cells.
- Orally bioavailable inhibitor of FAK1/PTK2
- Targets and inhibits PTK2 in an ATP-competitive manner
- Prevents PTK2-mediated downstream signaling
- Inhibits migration, proliferation, invasion, and survival in PTK2-overexpressing tumor cells
- Stable under recommended storage conditions
Medchemexpress LLC PF-06815345 hydrochloride | 2334434-49-8 | 98.15% | 634.49 | 10 MG
PF-06815345 hydrochloride is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. It significantly decreases the PCSK9 level in vivo in mouse. A clinical trial (NCT02654899) sponsored by Pfizer for Hypercholesterolemia started in November 2015 and is in Phase 1.
- Potent PCSK9 inhibitor with an IC50 of 13.4 μM.
- Significantly decreases PCSK9 levels in vivo.
- Shows CLint values of <82.9 μL/min/mg in human enterocytes and 97.6 μL/min/mg in human hepatocytes.
- Lowers plasma PCSK9 by 72% at 500 mg/kg in a humanized PCSK9 mouse model.
Ambeed 5 7Dihydroxy2 3hydroxy4methoxy
5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one, 520-34-3, 96%
Medchemexpress LLC H3R antagonist 1 hydrochloride | 2319790-07-1 | 377.87 | 1 ML
H3R antagonist 1 hydrochloride is a histamine receptor 3 (H3R) inverse agonist that can be utilized for the study of multiple sclerosis. It increases the expression levels of myelin-associated glycoprotein (MAG) and myelin basic protein (MBP) in differentiating oligodendrocytes, promoting oligodendrocyte precursor cell (OPC) differentiation in vitro.
- Promotes oligodendrocyte precursor cell (OPC) differentiation
- Increases expression of myelin-associated glycoprotein (MAG) and myelin basic protein (MBP)
- Enhances remyelination in demyelination models
- Increases Forskolin-stimulated cAMP level in primary OPCs
eMolecules 637031-88-0 | 3,3-Difluorocyclobutanol | Combi-Blocks | MFCD18791191 | 108.088 | C4H6F2O | 95.000 | OC1CC(F)(F)C1 | 10g | 439369317
3,3-Difluorocyclobutanol | Combi-Blocks | 637031-88-0 | MFCD18791191 | 108.088 | C4H6F2O | 95.000 | OC1CC(F)(F)C1 | 10g | 439369317
Medchemexpress LLC Nicotinimidamide hydrochloride | 7356-60-7 | 157.60 | 10 G
Nicotinimidamide hydrochloride (HY-W002264) is a laboratory chemical supplied by MedChemExpress, primarily utilized in the manufacture of various substances. It exhibits chemical stability under recommended storage conditions, ensuring product integrity.
- Stable under recommended storage conditions
- Store at 4°C, sealed, away from moisture and light
- Harmful if swallowed
- Causes skin and serious eye irritation
- May cause respiratory irritation
![eMolecules 128850-89-5 | N-[(3-Trimethoxysilyl)propyl]ethylenediamine triacetic acid trisodium salt (40% solution in water) | Oakwood Chemicals | MFCD00054460 | 462.413 | C14H25N2Na3O9Si | 0.000 | [Na+].[Na+].[Na+].CO[Si](CCCN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O)(OC)OC | 25g | 480171151](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000165160.jpg-250.jpg)
eMolecules 128850-89-5 | N-[(3-Trimethoxysilyl)propyl]ethylenediamine triacetic acid trisodium salt (40% solution in water) | Oakwood Chemicals | MFCD00054460 | 462.413 | C14H25N2Na3O9Si | 0.000 | [Na+].[Na+].[Na+].CO[Si](CCCN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O)(OC)OC | 25g | 480171151
N-[(3-Trimethoxysilyl)propyl]ethylenediamine triacetic acid trisodium salt (40% solution in water) | Oakwood Chemicals | 128850-89-5 | MFCD00054460 | 462.413 | C14H25N2Na3O9Si | 0.000 | [Na+].[Na+].[Na+].CO[Si](CCCN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O)(OC)OC | 25g | 480171151
Medchemexpress LLC Saxagliptin hydrochloride | 709031-78-7 | 99.7% | 351.87 | 50 MG
Saxagliptin hydrochloride is a potent, selective, reversible, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor with a Ki of 0.6-1.3 nM. It has potential for research into type 2 diabetes mellitus. It has been shown to induce β-cell proliferation, increase p-AKT and active β-catenin protein levels, and increase insulin secretion.
- Potent, selective, reversible, competitive, and orally active
- Inhibits dipeptidyl peptidase-4 (DPP-4) with a Ki of 0.6-1.3 nM
- Potential for type 2 diabetes mellitus research
- Induces β-cell proliferation
- Increases p-AKT and active β-catenin protein levels
- Increases insulin secretion and decreases glucagon secretion
Medchemexpress LLC Valnivudine hydrochloride | 956483-03-7 | 99.0% | 534.04 | 5 MG
FV-100 is a potent, selective, and orally active anti-varicella zoster virus agent. It is a proagent of CF-1743 and demonstrates very low toxicity in vivo.
- Potent and selective anti-varicella zoster virus (VZV) agent.
- Orally active.
- Exhibits very low toxicity in vivo.
- Intensely fluorescent when illuminated by wavelengths of 340-380 nm.
Medchemexpress LLC PF-00356231 hydrochloride | 820223-77-6 | 99.0% | 464.96 | 50 MG
PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12. It binds to MMP-12, forming a complex and shows potency against MMP-13, MMP-8, MMP-9, and MMP-3. Its activity can be significantly influenced by the presence of acetohydroxamate (AH).
- Specific, non-peptidic, non-zinc chelating ligand
- Inhibitor of matrix metalloproteinase MMP-12
- Potent against MMP-13, MMP-8, MMP-9, and MMP-3
- Activity affected by acetohydroxamate (AH)
Medchemexpress LLC (1R,2R)-2-PCCA hydrochloride | 1609563-71-4 | 98.1% | 528.56 | C30H39Cl2N3O | 25 MG
(1R,2R)-2-PCCA hydrochloride is the (1R,2R) diastereomer of 2-PCCA, a research-stage small molecule that functions as a GPR88 receptor agonist. It is used in in vitro pharmacology to characterize GPR88 activity and signaling and is supplied as a hydrochloride salt for laboratory assays.
- Potent GPR88 receptor agonist (EC50 = 3 nM in cell-free assay).
- Shows cellular activity with EC50 = 603 nM in cell-based assays.
- Inhibits GPR88-mediated cAMP production (EC50 = 56 nM) in HEK293 GPR88/GloSensor-22F assays.
- Molecular weight 528.56 and molecular formula C30H39Cl2N3O.
- High enantiomeric purity (98.1% ee) and reported purity 99.0%.
- Available in multiple vial sizes for laboratory research use.
Medchemexpress LLC (R)-Viloxazine hydrochloride | 56287-63-9 | MFCD00661100 | 99.1% | 273.76 g/mol | C13H20ClNO3 | 10MG
(R)-Viloxazine hydrochloride is the R-enantiomer of viloxazine hydrochloride supplied for research use. It is reported as a less active stereoisomer of the antidepressant viloxazine and is provided as a characterized small-molecule reagent with identity and purity data for laboratory studies.
- High purity (99.08%) with accompanying documentation.
- Provided as the hydrochloride salt for improved handling and solubility.
- Molecular formula C13H20ClNO3; molecular weight ~273.76 g/mol.
- Available in small-scale quantities suitable for preclinical or analytical work.
- For research use only; not for human or clinical use.
