Phenols
Sigma Aldrich Fine Chemicals Biosciences (R)-(−)-Phenylephrine Hydrochloride | 61-76-7 | MFCD00012605 | 5g
(R)-(−)-Phenylephrine Hydrochloride | Mol Wt: 203.67 | 61-76-7 | MFCD00012605 | 5g
Sigma Aldrich Fine Chemicals Biosciences (R)-(−)-Phenylephrine Hydrochloride | 61-76-7 | MFCD00012605 | 10g
(R)-(−)-Phenylephrine Hydrochloride | Mol Wt: 203.67 | 61-76-7 | MFCD00012605 | 10g
Apexbio Technology LLC Phenylephrine HCl 61-76-7 10mM (in 1mL DMSO)
Phenylephrine HCl (CAS 61-76-7) is a selective agonist of 1-adrenergic receptors a class of G protein-coupled receptors that mediate the effects of endogenous catecholamines such as norepinephrine and epinephrine Comparative studies indicate phenylephrine displays significant subtype selectivity with inhibitory pKi values of 4 87 4 70 and 5 86 for 1B- 1C- and 1A/D-adrenergic receptors respectively and agonist potencies (pEC50) of 6 47 6 77 and 7 01 for these subtypes In preclinical models phenylephrine has been shown to enhance alveolar fluid clearance and promote pulmonary edema absorption in ventilator-induced lung injury in a dose-dependent manner This compound is widely utilized in studies of adrenergic receptor signaling and pulmonary physiology
Sigma Aldrich Fine Chemicals Biosciences (R)-(-)-Phenylephrine hydrochloride powder | 61-76-7 | MFCD00012605 | 25G
(R)-(-)-Phenylephrine hydrochloride powder | Mol Wt: 203.67 | 61-76-7 | MFCD00012605 | 25G
Sigma Aldrich Fine Chemicals Biosciences (R)-(-)-Phenylephrine hydrochloride powder | 61-76-7 | MFCD00012605 | 100G
(R)-(-)-Phenylephrine hydrochloride powder | Mol Wt: 203.67 | 61-76-7 | MFCD00012605 | 100G
Sigma Aldrich Fine Chemicals Biosciences (R)-(-)-Phenylephrine hydrochloride powder | 61-76-7 | MFCD00012605 | 50G
(R)-(-)-Phenylephrine hydrochloride powder | Mol Wt: 203.67 | 61-76-7 | MFCD00012605 | 50G
Medchemexpress LLC 16α-Hydroxyestrone (16αOHE) | 566-76-7 | 99.7% | 286.37 | 1 ML
16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite classified as a human endogenous metabolite. It is used for research related to metabolic disease.
- Major estradiol metabolite
- Used for metabolic disease research
- Human endogenous metabolite
Medchemexpress LLC Arbutin (β-Arbutin) | 497-76-7 | 99.8% | 272.25 | 25 G
Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase and is used as a depigmenting agent. It is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possessing anti-oxidant, anti-inflammatory, and anti-tumor properties.
- Inhibits the viability of B16 murine melanoma cells in a time- and dose-dependent manner.
- Increases the apoptosis rate of B16 murine melanoma cells.
- Exhibits protective effects on isoproterenol-induced cardiac hypertrophy in mice.
- Ameliorates isoproterenol-induced myocardial injury.
eMolecules 3-Amino-2-chlorophenol | 56962-01-7 | MFCD11044694 | 250mg
Ambeed | 3-Amino-2-chlorophenol | 250mg | 602850772 | A796202 | | 56962-01-7 | MFCD11044694 | 143.570 | C6H6ClNO
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Medchemexpress LLC K-01-162 | 677746-25-7 | 98.0% | C15H14BrN | 1 ML
K 01-162, also known as K162, is an inhibitor designed to prevent the fibril formation of Aβ peptides and mitigate their neurotoxicity. This compound demonstrates binding affinity with Aβ42 peptide (EC50 of 80 nM) and directly with AβO (KD of 19 μM). It can penetrate the brain, making it a valuable tool for Alzheimer's disease research.
- Inhibits fibril formation of Aβ peptides
- Eliminates neurotoxicity of Aβ peptides
- Binds with Aβ42 peptide (EC50 of 80 nM)
- Binds directly to AβO (KD of 19 μM)
- Reduces intracellular AβO levels
- Blocks synaptic binding activity of AβO in mouse hippocampal neurons
- Attenuates amyloid load in vivo
- Capable of penetrating the brain
- Suitable for Alzheimer's disease research
Medchemexpress LLC Lorglumide sodium salt | 1021868-76-7 | 99.2% | 10 MM * 1 ML
Lorglumide sodium salt (CR-1409 sodium salt) is a potent cholecystokinin (CCK) receptor antagonist. It is intended for research use only.
- Potent cholecystokinin (CCK) receptor antagonist.
- For research use only.
Sigma Aldrich Fine Chemicals Biosciences Phenylephrine hydrochloride British Pharmacopoeia (BP) Reference Standard | 61-76-7 | MFCD00012605 |
Phenylephrine hydrochloride British Pharmacopoeia (BP) Reference Standard | Mol Wt: 203.67 | 61-76-7 | MFCD00012605 |
Medchemexpress LLC PF-8380 hydrochloride | 2070015-01-7 | 98.6% | 514.79 g/mol | C22H22ClN2O5S | 5 MG
PF-8380 hydrochloride is a small-molecule autotaxin (ATX) inhibitor supplied as a research reagent. It demonstrates potent inhibition in isolated enzyme assays and measurable activity in human whole blood, and is intended for laboratory research use only.
- Potent autotaxin inhibitor; IC50 2.8 nM in isolated enzyme assay.
- Active in human whole blood with IC50 ~101 nM.
- Molecular weight 514.79 g/mol and formula C22H22ClN2O5S.
- High purity (98.6%), suitable for biochemical and cellular assays.
- Available in small research pack sizes (1 mg, 5 mg, 10 mg).
- Intended for research use only; not for human or veterinary use.
Apexbio Technology LLC TA 01 1784751-18-3 10mM (in 1mL DMSO)
TA 01 (CAS 1784751-18-3) is a small molecule inhibitor that targets casein kinase 1 isoforms CK1 and CK1 as well as p38 MAPK It exhibits potent inhibitory activity with IC50 values of approximately 6 4 nM for CK1 6 8 nM for CK1 and 6 7 nM for p38 MAPK Through these actions TA 01 is utilized to investigate cellular signal transduction pathways and regulatory mechanisms of circadian rhythm It is particularly applicable in studies focused on pathophysiological processes associated with CK1 and p38 MAPK signaling including those related to cardiac signaling networks