Azoles
Medchemexpress LLC Agi-5198 (idh-c35) | 1355326-35-0 | 99.9% | 462.56 | 1 ML
AGI-5198 (IDH-C35) is a potent and selective mutant IDH1R132H inhibitor with an IC50 of 0.07 μM.
- Demonstrates dose-dependent inhibition of mutant IDH1 enzyme in TS603 glioma cells.
- Does not impair colony formation of patient-derived glioma lines expressing only wild-type IDH1.
- Reverses increased reactive oxygen species, DNA double-strand breaks, and cell death in IDH1(R132H) cancer cells exposed to ionizing radiation.
- Causes 50 to 60% growth inhibition of human glioma xenografts in vivo.
- Reduces Ki-67 protein staining in tumors from treated mice.
- Does not affect the growth of IDH1 wild-type glioma xenografts.
eMolecules 3034-53-5 | 2-Bromothiazole | Synthonix - Stock | MFCD00005316 | 164.020 | C3H2BrNS | 98.000 | Brc1nccs1 | 100g | 489891571
2-Bromothiazole | Synthonix - Stock | 3034-53-5 | MFCD00005316 | 164.020 | C3H2BrNS | 98.000 | Brc1nccs1 | 100g | 489891571
Accela Chembio Inc 2-methyl-4-(trifluoromethyl)thiazole-5-carboxylic Acid | 25g | 117724-63-7 | MFCD00173295 | 97+% | Shelf Life: 1440 Days | Light Sensitive/+4
2-methyl-4-(trifluoromethyl)thiazole-5-carboxylic Acid | 25g | 117724-63-7 | MFCD00173295 | 97+% | Shelf Life: 1440 Days | Light Sensitive/+4
AdipoGen Thiazole Orange Solution
Chemical. CAS 107091-89-4. Formula C26H24N2O3S2. MW 476.61. Thiazol Orange is a nucleic acid stain that has found applications in many different areas. Among others it is used for reticulocyte analysis and Plasmodium species analysis as well as labeling cancer cells. Thiazole orange-labeled DNA has been used for live cell RNA imaging. Thiazole Orange has also been used for a variety of assays, PCR and flow cytometry. Spectral data lambdaex=509nm, lambdaem=530nm in 0.1M phosphate pH 7.0 bound to dsDNA.
eMolecules 1194374-25-8 | 2-Bromo-5-methylthiazole-4-carboxylic acid | MFCD12404925 | 1g
Medchem Express | Birinapant | 5mg | 446267569 | HY-16591 | 1260251-31-7 | MFCD25976869 | 806.957 | C42H56F2N8O6
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC JQ-1 (carboxylic acid) | 202592-23-2 | 99.7% | 400.88 | 50 MG
JQ-1 carboxylic acid is a potent BET bromodomain inhibitor, derived from (+)-JQ-1. It is utilized for synthesizing PROTACs that target the degradation of BRD4. This compound is an off-white to yellow solid with a molecular weight of 400.88 and the chemical formula C19H17ClN4O2S.
- Potent BET bromodomain inhibitor.
- Used to synthesize PROTAC, targeting BRD4 degradation.
- Soluble in DMSO (100 mg/mL).
- Downregulates PD-L1 expression on B16F10 cells in vitro.
- Applicable in various disease areas including cancer, and signaling pathways such as epigenetics and immunology/inflammation.
- Store powder at -20°C for 3 years or 4°C for 2 years.
Accela Chembio Inc Methyl 2-aminothiazole-5-carboxylate | 5g | 6633-61-0 | MFCD03788562 | 95+% | Shelf Life: 1260 Days | Light Sensitive
Methyl 2-aminothiazole-5-carboxylate | 5g | 6633-61-0 | MFCD03788562 | 95+% | Shelf Life: 1260 Days | Light Sensitive
Medchemexpress LLC 5-Azidopentanoic acid | 79583-98-5 | 99.77% | 25 MG
5-Azidopentanoic acid (also known as 5-Azidovaleric acid) is an organic acid primarily utilized in click chemistry reactions. It is intended for research use only and is not sold for patient administration.
- Organic acid
- Suitable for click chemistry reactions
- For research use only
- Categorized as a biochemical assay reagent
- Purity of 99.77%
- Light yellow to brown liquid appearance
eMolecules Thiazole-5-carboxylic acid | Combi-Blocks | 14527-41-4 | MFCD03428539 | 129.130 | C4H3NO2S | 98.000 | OC(=O)c1cncs1 | 1g | 117533853
Thiazole-5-carboxylic acid | Combi-Blocks | 14527-41-4 | MFCD03428539 | 129.130 | C4H3NO2S | 98.000 | OC(=O)c1cncs1 | 1g | 117533853
eMolecules 3034-53-5 | 2-Bromothiazole | Oakwood Chemicals | MFCD00005316 | 164.020 | C3H2BrNS | 99.000 | Brc1nccs1 | 500g | 480117573
2-Bromothiazole | Oakwood Chemicals | 3034-53-5 | MFCD00005316 | 164.020 | C3H2BrNS | 99.000 | Brc1nccs1 | 500g | 480117573
eMolecules 40283-41-8 | 2-Aminothiazole-4-carboxylic acid | AA Blocks LLC | MFCD00859429 | 144.150 | C4H4N2O2S | 0.000 | Nc1nc(cs1)C(O)=O | 5g | 410195609
2-Aminothiazole-4-carboxylic acid | AA Blocks LLC | 40283-41-8 | MFCD00859429 | 144.150 | C4H4N2O2S | 0.000 | Nc1nc(cs1)C(O)=O | 5g | 410195609
eMolecules 60845-81-0 | Ethyl 2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetate | Apollo Scientific215.230 | C7H9N3O3S | 95.000 | CCOC(=O)C(=NO)c1csc(N)n1 | 5g | 562458856
Ethyl 2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetate | Apollo Scientific | 60845-81-0215.230 | C7H9N3O3S | 95.000 | CCOC(=O)C(=NO)c1csc(N)n1 | 5g | 562458856
Medchemexpress LLC Aminothiazole (2-aminothiazole) | 96-50-4 | MFCD00005325 | 99.8% | 100.14 g/mol | C3H4N2S | 100G
Aminothiazole (2-aminothiazole, CAS 96-50-4) is a heterocyclic amine used as a versatile building block in organic synthesis. It is employed as a precursor for sulfur-containing agents and biologically active molecules, and can act as a reaction accelerator. The compound has molecular formula C3H4N2S, molecular weight 100.14 g/mol, and is supplied as a white to off-white crystalline solid with high analytical purity.
Medchemexpress LLC AGI-5198 | 1355326-35-0 | 99.9% | 462.56 | 50 MG
AGI-5198 (IDH-C35) is a potent and selective mutant IDH1R132H inhibitor with an IC50 of 0.07 μM. It is designed for research use only.
- Potent and selective mutant IDH1R132H inhibitor.
- Inhibits mutant IDH1 enzyme in TS603 glioma cells.
- Does not impair colony formation of wild-type IDH1 glioma lines.
- Reverses increased reactive oxygen species, DNA double-strand breaks, and cell death after ionizing radiation in IDH1(R132H) mutated cancer cells.
- Causes significant growth inhibition of human glioma xenografts in vivo.
Medchemexpress LLC 2-Bromothiazole | 3034-53-5 | 164.02 | 25 G
2-Bromothiazole is a biochemical reagent used as a biological material or organic compound for life science related research. It is intended for research purposes only. It is also utilized as an Aryl halide for N-arylation of 5- and 7-azaindoles, and copper-catalyzed cyanation provides 2-cyanothiazole.
- Used as a biochemical reagent
- Applicable as a biological material or organic compound in life science research
- Can be used as an Aryl halide