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Organic compounds that consist of a benzoic acid with an acylamino substitution; an acylamino substitution consists of a carbon atom bonded to a carbonyl group that is bonded to a nitrogen atom bonded to a hydrogen atom and an organic group.
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4-Acetamido-5-chloro-2-methoxybenzoic acid is a benzoic-acid derivative used as a drug intermediate and analytical impurity reference in medicinal chemistry and process development. It is supplied for research use where high chemical purity and traceable analytical documentation are required.
High purity (99.39% by LCMS).
Molecular formula C10H10ClNO4.
Molecular weight 243.65 g·mol⁻¹.
Suitable as a drug intermediate and impurity reference standard.
Supplied with certificate of analysis and safety data sheet for traceability.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PF-05212384 (PKI-587) is a dual inhibitor targeting both phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) It exhibits potent inhibitory activity targeting PI3K isoforms with IC50 values of 0 4 nM 6 nM 8 nM and 6 nM respectively as well as mTOR at 1 4 nM Furthermore PF-05212384 effectively suppresses mutant PI3K forms including the H1047R and E545K mutations In cell-based assays this compound inhibits PI3K/mTOR signaling pathways evidenced by decreased phosphorylation of downstream proteins Akt GSK3 eNOS and PRAS40 PF-05212384 has demonstrated anti-tumor effects in various xenograft tumor models thus serving as a useful tool molecule for investigating PI3K/mTOR pathway functions and related oncology studies
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More