Aminobenzoic acids and derivatives
Chemscene Taniaphos sl-t001-1 | 250mg | CS-0031503 | 98% | 1003012-96-1 | MFCD04117709 | 687 57 | C43H39FeNP2
Chemscene | Taniaphos sl-t001-1 | 250mg | CS-0031503 | 98% | 1003012-96-1 | MFCD04117709 | 687 57 | C43H39FeNP2
Aobchem 4-Borono-2 5-dimethylbenzoic acid | 97% | C9H11BO4 | 250mg
4-Borono-2 5-dimethylbenzoic acid | 97% | C9H11BO4 | 250mg
Chemscene 2-Cyclopropyl-4 4 5 5-tetramethyl-1 3 2-dioxaborolane | 5g | CS-W007591 | 98% | 126689-01-8 | MFCD05663847 | 168 04 | C9H17BO2
Chemscene | 2-Cyclopropyl-4 4 5 5-tetramethyl-1 3 2-dioxaborolane | 5g | CS-W007591 | 98% | 126689-01-8 | MFCD05663847 | 168 04 | C9H17BO2
Medchemexpress LLC Ac-IEPD-CHO | 352520-90-2 | 99.2% | 498.53 | 10 MG
Ac-IEPD-CHO is a reversible inhibitor of granzyme B, with a reported Ki of 80 nM. It also acts as a caspase-8 inhibitor.
- Reversible granzyme B inhibitor.
- Ki of 80 nM against granzyme B.
- Caspase-8 inhibitor.
- In vitro studies show Ac-IEPD-CHO (35-50 μg/mL, 1 h pretreatment followed by 16 h) diminishes Th17-polarized cells induced MO3.13 cell death.
Medchemexpress LLC NAMI-A | 201653-76-1 | 98.0% | 458.18 | 1 ML
NAMI-A is a ruthenium-based drug characterized by its selective activity against tumor metastases, and it inhibits adhesion and migration.
- Significantly affects tumor cells with metastatic ability.
- Half-life of elimination from the lungs is longer than for the liver, kidney, and primary tumor.
- Active on tumor cells when bound to collagen, as shown by an in vitro invasion test.
- Inhibits matrix metalloproteinases MMP-2 and MMP-9 at micromolar concentrations.
- Inhibits the adhesion and migration of colorectal cancer cells.
- Decreases α5β1 integrin expression and FAK auto-phosphorylation on Tyr 397.
- Reference dose for in vivo studies is 35 mg/kg/day.
eMolecules 1423-26-3 | 3-(Trifluoromethyl)phenylboronic Acid | Accela ChemBio (ASD) | MFCD00151854 | 189.930 | C7H6BF3O2 | 98.000 | OB(O)c1cccc(c1)C(F)(F)F | 25g | 452412294
3-(Trifluoromethyl)phenylboronic Acid | Accela ChemBio (ASD) | 1423-26-3 | MFCD00151854 | 189.930 | C7H6BF3O2 | 98.000 | OB(O)c1cccc(c1)C(F)(F)F | 25g | 452412294
eMolecules 127946-77-4 | 1-Amino-1-cyclopropanecarbonitrile hydrochloride | Chem-Impex | MFCD04114063 | 118.560 | C4H7ClN2 | 97.000 | Cl.NC1(CC1)C#N | 100g | 462126657
1-Amino-1-cyclopropanecarbonitrile hydrochloride | Chem-Impex | 127946-77-4 | MFCD04114063 | 118.560 | C4H7ClN2 | 97.000 | Cl.NC1(CC1)C#N | 100g | 462126657
Medchemexpress LLC Ac-Exatecan | 2922852-48-8 | 99.0% | C26H24FN3O5 | 50 MG
Ac-Exatecan is an acetylation-modified Exatecan, which acts as a common toxin component in Antibody-Drug Conjugate (ADC) preparation and is an inhibitor of DNA topoisomerase I (IC50 = 2.2 μM). This compound demonstrates antitumor activity and can serve as a payload for ADCs. Furthermore, Exatecan is effective against P-glycoprotein-mediated multi-drug resistant cells. This product is for research use only.
- Acetylation-modified Exatecan
- Common toxin component in antibody-drug conjugate (ADC) preparation
- Inhibitor of DNA topoisomerase I (IC50 = 2.2 μM)
- Demonstrates antitumor activity
- Can serve as a payload for ADCs
- Effective against P-glycoprotein-mediated multi-drug resistant cells
Medchemexpress LLC 4-Acetamidophenyl acetate | 2623-33-8 | >=97.0% | C10H11NO3 | 1 ML
4-Acetamidophenyl acetate is an impurity of Acetaminophen and acts as an intermediate in its synthesis. It is classified as harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation.
- Selective COX-2 inhibitor (IC50=25.8 μM)
- Potent hepatic N-acetyltransferase 2 (NAT2) inhibitor
- Undergoes hydrolytic cleavage independent of microsomes and cofactors in rat liver microsomal metabolism assays in vitro
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
Medchemexpress LLC p-Hydroxymandelic acid | 1198-84-1 | 95.5% | 168.15 | 500 MG
p-Hydroxymandelic acid is a valuable aromatic fine chemical and widely used for production of pharmaceuticals and food additives. It is also used in the production of aromatic drugs and flavors, and for the preparation of 4-hydroxyphenylacetic acid, a synthetic precursor of the selective β1-receptor antagonist drug atenolol. Additionally, p-Hydroxymandelic acid can conjugate cytotoxic drugs and enzyme substrates, suggesting its application in targeted drug delivery systems.
- Valuable aromatic fine chemical.
- Used for production of pharmaceuticals.
- Used for production of food additives.
- Applied in targeted drug delivery systems.
Chemscene 3-Bromo-2-methoxybenzoic acid | 25g | CS-W008368 | 98% | 101084-39-3 | MFCD00045840 | 231 04 | C8H7BrO3
Chemscene | 3-Bromo-2-methoxybenzoic acid | 25g | CS-W008368 | 98% | 101084-39-3 | MFCD00045840 | 231 04 | C8H7BrO3
eMolecules 819057-45-9 | (4-AMINO-2-FLUOROPHENYL)BORONIC ACID PINACOL ESTER | AstaTech | MFCD09951877 | 237.080 | C12H17BFNO2 | 95.000 | CC1(C)OB(OC1(C)C)c1ccc(N)cc1F | 10g | 268485909
(4-AMINO-2-FLUOROPHENYL)BORONIC ACID PINACOL ESTER | AstaTech | 819057-45-9 | MFCD09951877 | 237.080 | C12H17BFNO2 | 95.000 | CC1(C)OB(OC1(C)C)c1ccc(N)cc1F | 10g | 268485909
Medchemexpress LLC 7-chlorokynurenic acid | 18000-24-3 | MFCD00069227 | 223.61 | C10H6ClNO3 | 5 MG
7-Chlorokynurenic acid is a research tool compound used to probe NMDA receptor function by selectively antagonizing the glycine coagonist site. It also inhibits vesicular glutamate uptake and has reported antinociceptive effects in certain delivery models, making it useful for neuropharmacology and synaptic signaling studies.
- Potent and selective antagonist of NMDA receptor glycine site.
- Inhibits glutamate reuptake into synaptic vesicles.
- Suitable for in vitro and in vivo research applications.
- Supplied as a powder for flexible preparation and dosing.
- Stable under frozen storage for extended periods when handled per datasheet.