Benzenesulfonamides
Medchemexpress LLC Glimepiride | 93479-97-1 | 99.9% | C24H34N4O5S | 10 MM * 1 ML
Glimepiride is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg. It is for research use only. It has been shown to decrease extracellular Aβ40 and Aβ42 levels, potentially serving as a promising drug for the treatment of AD associated with diabetes. Compared to other sulfonylureas, it is generally associated with a lower risk of hypoglycemia and less weight gain, and may be safer for patients with cardiovascular disease due to its lack of detrimental effects on ischemic preconditioning.
- Medium-to-long acting sulfonylurea anti-diabetic compound
- Lowers blood glucose in rabbits more effectively than glibenclamide
- Associated with lower risk of hypoglycemia and less weight gain
- May be safer for patients with cardiovascular disease
Medchemexpress LLC HY-10409 10mg Medchemexpress, Fedratinib CAS:936091-26-8 Purity:>98%
Medchemexpress, HY-10409 10mg Fedratinib CAS:936091-26-8 Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B1781 250mg Medchemexpress, Sulfachloropyridazine CAS:80-32-0 Purity:>98%
Medchemexpress, HY-B1781 250mg Sulfachloropyridazine CAS:80-32-0 Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10341 500mg , Fasudil (Hydrochloride) HA-1077;AT-877;Fasudil HCl CAS:105628-07-7 Purity:98%
Medchemexpress, HY-10341 500mg Fasudil (Hydrochloride) HA-1077;AT-877;Fasudil HCl CAS:105628-07-7 Formula:C14H18ClN3O2S Ki: 0.33 μM (ROCK1), 1.0 μM (PKA), 9.3 μM (PKC), 55 μM (MLCK) [8] Purity:98% Fasudil Hydrochloride is a potent inhibitor of ROCK1 , PKA , PKC , and MLCK with K i of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15531 50mg Medchemexpress, Venetoclax CAS:1257044-40-8 Purity:>98%
Medchemexpress, HY-15531 50mg Venetoclax CAS:1257044-40-8 Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM. Venetoclax induces autophagy[2][3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC PI3K-IN-1 (XL-147 derivative 1) | 1349796-36-6 | 99.9% | 100MG
PI3K-IN-1 (XL-147 derivative 1) | 1349796-36-6 | 99.9% | 100MG
Sigma Aldrich Fine Chemicals Biosciences Zafirlukast >=98% (HPLC) | 107753-78-6 | MFCD00864775 | 10MG
Zafirlukast >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 575.68 | 107753-78-6 | MFCD00864775 | 10MG
Medchemexpress LLC Deltasonamide 2 hydrochloride | 2448341-55-5 | 99.8% | 50MG
Deltasonamide 2 hydrochloride | 2448341-55-5 | 99.8% | 50MG
![eMolecules Medchem Express / CD73-IN-1 / 1mg / 446258343 / HY-103695 / / 2132396-40-6 / [null] / 371.410 / C18H17N3O4S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502457338.PNG-250.jpg)
eMolecules Medchem Express / CD73-IN-1 / 1mg / 446258343 / HY-103695 / / 2132396-40-6 / [null] / 371.410 / C18H17N3O4S
Medchem Express / CD73-IN-1 / 1mg / 446258343 / HY-103695 / / 2132396-40-6 / [null] / 371.410 / C18H17N3O4S
Sigma Aldrich Fine Chemicals Biosciences N-Chlorobenzenesulfonamide sodium salt ~28% active chlorine basis | 127-52-6 | MFCD00149552 | 500G
N-Chlorobenzenesulfonamide sodium salt ~28% active chlorine basis | Purity: ~28% active chlorine basis | 127-52-6 | MFCD00149552 | 500G
Medchemexpress LLC Xmu-mp-3 | 2031152-08-4 | 95.7% | C27H27F3N8O | 10MG
XMU-MP-3 is a potent, non-covalent inhibitor of Bruton's tyrosine kinase (BTK) that inhibits both wild-type BTK and the C481S mutant. It demonstrates low-nanomolar biochemical potency and cellular activity, including induction of apoptosis, and is suitable for biochemical and cellular studies of BTK signaling and inhibitor profiling.
- Low-nanomolar biochemical potency (IC50 10.7 nM for BTK WT, 17.0 nM for BTK C481S in the presence of 10 μM ATP).
- Demonstrated cellular activity (BTK-transformed Ba/F3 proliferation IC50 11.4 nM).
- Induces apoptosis in BTK-dependent cell models.
- High chemical purity (95.7%).
- Defined storage stability for powder and solutions.
- Suitable for biochemical assays and cellular mechanistic studies.
Sigma Aldrich Fine Chemicals Biosciences Oxamflatin >=98% (HPLC), solid | 151720-43-3 | MFCD00949087 | 5MG
Oxamflatin >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 342.37 | 151720-43-3 | MFCD00949087 | 5MG
Cayman Chemical N-desmethyl SIldenafIl 50mg
A major metabolite of sildenafil; formed via oxidative metabolism of sildenafil by CYP3A4, CYP3A5, and CYP3A7
Sigma Aldrich Fine Chemicals Biosciences SC-236 >=98% (HPLC) | 170569-86-5 | MFCD00941297 | 5MG
SC-236 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 401.79 | 170569-86-5 | MFCD00941297 | 5MG