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Filtered Search Results
eMolecules 330161-87-0 | SU6656 | MFCD10565928 | 50mg
Ambeed | 3-(Furan-2-ylmethyl)-18-dimethyl-1H-purine-26(3H7H)-dione | 1mg | 598442356 | A389771 | 80288-49-9 | MFCD00153799 | 260.253 | C12H12N4O3
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Medchemexpress LLC HY-113973 5mg Medchemexpress, LPA2 antagonist 2 CAS:36840-10-5 Purity:>98%
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Medchemexpress, HY-113973 5mg LPA2 antagonist 2 CAS:36840-10-5 LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM, which is >480-fold more selective than LPA3 (IC50 of 13.85 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 608512-97-6 | Medchem Express | PKR-IN-C16 | 5mg | 705860907 | HY-13977A | MFCD28135662 | 268.29 | C13H8N4OS
Medchem Express | PKR-IN-C16 | 5mg | 705860907 | HY-13977A | 608512-97-6 | MFCD28135662 | 268.290 | C13H8N4OS
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Selleck Chemical LLC Sulfasalazine S1576-1g
Sulfasalazine is a sulfa derivative of mesalazine used as an anti-inflammatory agent to treat bowel disease and rheumatoid arthritis Sulfasalazine is a potent and specific inhibitor of nuclear factor kappa B (NF- B) TGF- and COX-2 Sulfasalazine induces ferroptosis apoptosis and autophagy
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Apexbio Technology LLC Glimepiride 93479-97-1 10mM (in 1mL DMSO)
Glimepiride (CAS 93479-97-1) is a sulfonylurea compound widely used in research on type 2 diabetes It primarily acts by enhancing glucose uptake both in the presence and absence of insulin In cultured cells glimepiride (10 M) increases 2-deoxyglucose uptake to 186% of control and upregulates GLUT1 and GLUT4 expression to 164% and 148% of control respectively indicating insulin-independent mechanisms for stimulating cardiac glucose uptake In rodent models glimepiride administration reduced diabetes incidence by 23% in BB rats and decreased blood glucose HbA1c and plasma insulin levels in KK-Ay mice highlighting its utility for investigating glucose metabolism and diabetes pathophysiology
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Medchemexpress LLC H-1152 dihydrochloride | 871543-07-6 | 99.1% | 392.34 g/mol | C16H23Cl2N3O2S | 10 MG
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H-1152 dihydrochloride is a membrane-permeable, selective inhibitor of Rho-associated protein kinases (ROCK), reported with a Ki of 1.6 nM and an IC50 of 12 nM for ROCK2. Supplied as the dihydrochloride salt in solid form, it is intended for research use and offers formulation options for both in vitro and in vivo studies.
- Potent inhibition of ROCK family kinases (Ki = 1.6 nM; IC50 ROCK2 = 12 nM).
- Membrane-permeable for cellular assays.
- High purity suitable for research applications.
- Multiple solubility and formulation options for in vitro and in vivo use.
- Available in small solid quantities convenient for laboratory experiments.
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Medchemexpress LLC Sildenafil citrate | 171599-83-0 | MFCD09026931 | C22H30N6O4S ·C6H8O7 | 500 MG
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Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It has demonstrated efficacy in potentiating the phosphorylation of ERK1/ERK2, promoting cell proliferation, and enhancing the upregulation of ERK1/ERK2 phosphorylation induced by serotonin in in vitro studies. In vivo, Sildenafil citrate has been shown to significantly increase intracavernosal pressure (ICP) and ICP/blood pressure (BP) in dog models of erection, and it has been reported to decrease flap necrosis in preclinical animal models.
- Potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM
- Potentiates ERK1/ERK2 phosphorylation in vitro
- Promotes cell proliferation and enhances ERK1/ERK2 phosphorylation induced by serotonin
- Increases intracavernosal pressure (ICP) and ICP/BP in dog models of erection
- Reported to decrease flap necrosis in preclinical animal models
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Selleck Chemical LLC Furosemide S1603-50mg
Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor used in the treatment of congestive heart failure and edema
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eMolecules 402713-81-9 | Medchem Express | SB-399885 hydrochloride | 5mg | 446257985 | HY-103099 | MFCD09970355 | 482.8 | C18H22Cl3N3O4S
Medchem Express | BPU-11 | 5mg | 784543790 | HY-119102 | 909664-41-1 | 501.634 | C32H31N5O
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Medchemexpress LLC HY-112060 10mg Medchemexpress, Saccharin 1-methylimidazole CAS:482333-74-4 Purity:>98%
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Medchemexpress, HY-112719B 10mg BRD 4354 (ditrifluoroacetate) CAS: BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0.85 and 1.88 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112909A 10mg Medchemexpress, UAMC-3203 hydrochloride CAS:2271358-65-5 Purity:>98%
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Medchemexpress, HY-112909A 10mg UAMC-3203 HCl CAS:2271358-65-5 UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 701-34-8 | 4-BROMOBENZENESULFONAMIDE | AstaTech | MFCD00051977 | 236.080 | C6H6BrNO2S | 95.000 | NS(=O)(=O)c1ccc(Br)cc1 | 25g | 323616763
4-BROMOBENZENESULFONAMIDE | AstaTech | 701-34-8 | MFCD00051977 | 236.080 | C6H6BrNO2S | 95.000 | NS(=O)(=O)c1ccc(Br)cc1 | 25g | 323616763
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eMolecules 701-34-8 | 4-Bromobenzenesulfonamide | ChemScene | MFCD00051977 | 236.080 | C6H6BrNO2S | 98.000 | NS(=O)(=O)c1ccc(Br)cc1 | 10g | 894453058
4-Bromobenzenesulfonamide | ChemScene | 701-34-8 | MFCD00051977 | 236.080 | C6H6BrNO2S | 98.000 | NS(=O)(=O)c1ccc(Br)cc1 | 10g | 894453058
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eMolecules 2831-66-5 | 2,4-dichloro-1,3,5-triazine | Pharmablock | MFCD04115347 | 149.960 | C3HCl2N3 | 97.000 | Clc1ncnc(Cl)n1 | 500mg | 551204045
2,4-dichloro-1,3,5-triazine | Pharmablock | 2831-66-5 | MFCD04115347 | 149.960 | C3HCl2N3 | 97.000 | Clc1ncnc(Cl)n1 | 500mg | 551204045
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eMolecules 873-41-6 | 3,5,6-TRICHLORO-1,2,4-TRIAZINE | AstaTech | MFCD09033774 | 184.400 | C3Cl3N3 | 95.000 | Clc1nnc(Cl)c(Cl)n1 | 1g | 480080110
3,5,6-TRICHLORO-1,2,4-TRIAZINE | AstaTech | 873-41-6 | MFCD09033774 | 184.400 | C3Cl3N3 | 95.000 | Clc1nnc(Cl)c(Cl)n1 | 1g | 480080110
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