Benzenesulfonamides
Chemscene ChemScene | 2,4-Difluorobenzenesulfonamide | 10G | CS-W010691 | 0.98 | 13656-60-5| MFCD01320743 | 193.17
ChemScene | 2,4-Difluorobenzenesulfonamide | 10G | CS-W010691 | 0.98 | 13656-60-5| MFCD01320743 | 193.17
Apexbio Technology LLC Sulfacetamide Sodium 127-56-0 5g
Sulfacetamide Sodium (127-56-0) is a small-molecule inhibitor targeting bacterial dihydropteroate synthase It is designed to competitively inhibit this enzyme thereby disrupting bacterial folic acid synthesis Sulfacetamide Sodium exerts its biological activity primarily through inhibition of bacterial dihydropteroate synthase In in vitro studies Sulfacetamide Sodium demonstrates bacteriostatic activity with inhibitory concentrations (IC50) ranging from 60 g/mL to 64 mg/mL dependent on the bacterial species studied Based on these pharmacological properties Sulfacetamide Sodium holds research potential in microbiological studies of antibacterial potency antibiotic susceptibility and resistance patterns
Apexbio Technology LLC Sildenafil 139755-83-2 200mg
Sildenafil (CAS 139755-83-2) is a small molecule inhibitor of phosphodiesterase type 5 (PDE5) By selectively blocking PDE5 activity sildenafil increases intracellular levels of cyclic guanosine monophosphate (cGMP) thereby modulating smooth muscle relaxation The compound exhibits an IC50 value of 5 22 nM against PDE5 indicating high potency in enzymatic assays Sildenafil is widely utilized in biomedical research to study cGMP signaling pathways and vascular smooth muscle physiology as well as to evaluate mechanisms underlying vasodilation and related pathophysiological conditions
Selleck Chemical LLC CA3
CA3 (CIL56) has potent inhibitory effects on YAP1/Tead transcriptional activity and primarily targets YAP1 high and therapy-resistant esophageal adenocarcinoma cells endowed with CSC properties CA3(CIL56) induces ferroptosis and iron-dependent reactive oxygen species (ROS)
Apexbio Technology LLC Sildenafil Citrate 171599-83-0 50mg
Sildenafil Citrate is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) PDE5 mediates degradation of cGMP a signaling molecule regulating smooth muscle tone vascular dilation and blood flow By inhibiting PDE5 Sildenafil Citrate elevates intracellular cGMP levels It has an IC50 value of approximately 3 6 nM against PDE5 Pharmacologically Sildenafil Citrate induces relaxation of smooth muscle tissues including penile corpus cavernosum and vascular smooth muscle thus facilitating increased blood flow It is widely utilized in biomedical research involving erectile dysfunction therapies and the management of pulmonary arterial hypertension (PAH)
Chem-Impex International, Inc. Ribonucleic acid (from torula yeast) | 63231-63-0 | MFCD00132195 | 25G
Ribonucleic acid (from torula yeast), 63231-63-0, MFCD00132195, 25G
AdipoGen Glimepiride (1 g)
Chemical. CAS: 93479-97-1. Formula: C24H34N4O5S. MW: 490.62. Glimepiride is a long-acting sulfonylurea antidiabetic agent inhibiting ATP-sensitive potassium (KATP) channels in pancreatic beta-cells, which leads to the release of insulin. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle suggest that Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase and stimulates glucose transporter 1 and 4 (GLUT1/4) expression. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway and exhibits neuroprotective benefit, decreasing expression and activity of BACE1 and amyloid-beta (Abeta) in neurons in a PPARgamma-dependent manner.
STA PHARMACEUTICAL US LLC 4-(Fmoc-amino)-1-methyl-1H-imidazole-2-carboxylic acid | 1 g | CAS 252206-28-3 | MDL MFCD02259498
4-(Fmoc-amino)-1-methyl-1H-imidazole-2-carboxylic acid is a Amino Acid reagent (Subcategory: Aryl AA) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 252206-28-3
- MDL: MFCD02259498
- InChIKey: AFUJLUWSTBUALR-UHFFFAOYSA-N
- Molecular Weight: 363.373
- Molecular Formula: C20H17N3O4
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29332990
- Country Of Origin: China
- IUPAC: 4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-1-methyl-1H-imidazole-2-carboxylic acid
- SMILES: CN1C=C(N=C1C(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O
Electron Microscopy Sciences SEM Scintillator YAP 19.8x1 mm
YAP (Yttrium Aluminum Perovskite activated by Ce3+) shares the same advantages as YAG but is more efficient in terms of light output than YAG crystals. As well, the emission spectrum peaks at about 378nm, and this corresponds closely to the maximum sensitivity of the S11 photocathode which in general is used in most scanning electron microscopes. (There would be more improvement in signal by using a YAP crystal rather than YAG in these microscopes). The decay time of YAP (40ns) is faster than YAG (80ns) so its overall performance is superior to YAG.
YAP crystals should be coated with 50nm of aluminum prior to use. Note: P-47 is usually in-stock. YAG and YAP delivery time is 6-8 weeks. Use with Hitachi w/metal ring.
Apexbio Technology LLC Sildenafil Citrate 171599-83-0 10mM (in 1mL DMSO)
Sildenafil Citrate is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) PDE5 mediates degradation of cGMP a signaling molecule regulating smooth muscle tone vascular dilation and blood flow By inhibiting PDE5 Sildenafil Citrate elevates intracellular cGMP levels It has an IC50 value of approximately 3 6 nM against PDE5 Pharmacologically Sildenafil Citrate induces relaxation of smooth muscle tissues including penile corpus cavernosum and vascular smooth muscle thus facilitating increased blood flow It is widely utilized in biomedical research involving erectile dysfunction therapies and the management of pulmonary arterial hypertension (PAH)
Electron Microscopy Sciences SEM Scintillator YAP 16.4x17 mm
YAP (Yttrium Aluminum Perovskite activated by Ce3+) shares the same advantages as YAG but is more efficient in terms of light output than YAG crystals. As well, the emission spectrum peaks at about 378nm, and this corresponds closely to the maximum sensitivity of the S11 photocathode which in general is used in most scanning electron microscopes. (There would be more improvement in signal by using a YAP crystal rather than YAG in these microscopes). The decay time of YAP (40ns) is faster than YAG (80ns) so its overall performance is superior to YAG.
YAP crystals should be coated with 50nm of aluminum prior to use. Note: P-47 is usually in-stock. YAG and YAP delivery time is 6-8 weeks. Use with Novascan, SEMCO/Zeiss scanning electron microscopes.