Benzenesulfonamides
Medchemexpress LLC HY-108324 5mg Medchemexpress, (Z)-Thiothixene CAS:3313-26-6 Purity:>98%
Medchemexpress, HY-108324 5mg (Z)-Thiothixene CAS:3313-26-6 (Z)-Thiothixene is an antagonist of serotonergic receptor extracted from patent US 20150141345 A1. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Sildenafil 139755-83-2 50mg
Sildenafil (CAS 139755-83-2) is a small molecule inhibitor of phosphodiesterase type 5 (PDE5) By selectively blocking PDE5 activity sildenafil increases intracellular levels of cyclic guanosine monophosphate (cGMP) thereby modulating smooth muscle relaxation The compound exhibits an IC50 value of 5 22 nM against PDE5 indicating high potency in enzymatic assays Sildenafil is widely utilized in biomedical research to study cGMP signaling pathways and vascular smooth muscle physiology as well as to evaluate mechanisms underlying vasodilation and related pathophysiological conditions
Medchemexpress LLC HY-15206 5g , Glibenclamide Glyburide CAS:10238-21-8 Purity:98%
Medchemexpress, HY-15206 5g Glibenclamide Glyburide CAS:10238-21-8 Formula:C23H28ClN3O5S Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
TARGETMOL CHEMICALS INC SEMUSTINE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Semustine a DNA alkylating agent is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia. purity: 99%
Apexbio Technology LLC Sildenafil mesylate 1308285-21-3 50mg
Sildenafil mesylate (CAS 1308285-21-3) is a potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) exhibiting an IC50 of 3 5 nM By inhibiting PDE5-mediated cGMP hydrolysis it enhances endogenous cGMP levels particularly within corpus cavernosum tissue In vitro sildenafil mesylate reversibly potentiates relaxation responses in precontracted corpus cavernosum strips following sodium nitroprusside exposure or electrical stimulation and increases intracellular cGMP in treated smooth muscle cells In vivo it augments erectile responses in anesthetized canine models This compound is widely used for studying PDE5-related signaling pathways and pharmacological modulation in erectile and vascular function research
eMolecules 2132396-40-6 | Medchem Express | CD73-IN-1 | 1mg | 446258343 | HY-103695 | 371.41 | C18H17N3O4S
Ambeed | Benzo[c][125]oxadiazol-5-ylboronic acid | 100mg | 490552947 | A311681 | 426268-09-9 | MFCD07186239 | 163.930 | C6H5BN2O3
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Cayman Chemical SIldenafIl Chlorosulfonyl 1g
An intermediate in the synthesis of sildenafil; a potential impurity found in commercial preparations of sildenafil
Medchemexpress LLC Sildenafil citrate | 171599-83-0 | C28H38N6O11S | 1 G
Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It is for research use only.
- Potent phosphodiesterase type 5 (PDE5) inhibitor.
- Potentiates phosphorylation of ERK1/ERK2 in vitro.
- Increases percentage of cells in S phase and enhances cell proliferation in vitro.
- Significantly increases intracavernosal pressure (ICP) in a dog model of erection in vivo.
- Reduces the number of TL+-cells in vivo.
- Decreases flap necrosis in preclinical animal models by increasing secretion of growth factors (FGF and VEGF).
Medchemexpress LLC Bosentan | 147536-97-8 | 99.9% | C27H29N5O6S | 1 ML
Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors, with Ki values of 4.7 nM and 95 nM in human SMC, respectively. It is for research use only.
- Competitive and dual antagonist of endothelin-1 (ET)
- Acts on ETA and ETB receptors
- Research use only
Medchemexpress LLC HY-15039 5mg Medchemexpress, SSR240612 CAS:464930-42-5 Purity:>98%
Medchemexpress, HY-15039 5mg SSR240612 CAS:464930-42-5 SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist, with Kis of 0.48 nM and 0.73 nM for B1 kinin receptors of human fibroblast MRC5 and HEK cells expressing human B1 receptors, 481 nM and 358 nM for B2 receptors of guinea pig ileum membranes and CHO cells expressing human B1 receptor, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC SB 258719 | 195199-95-2 | 338.51 | 50 MG
SB 258719 is a selective 5-HT7 receptor antagonist with a high affinity (pKi=7.5) for the receptor. It can be used for research in cancer and neurological diseases.
- Selective 5-HT7 receptor antagonist
- High affinity for the receptor (pKi=7.5)
- Suitable for research in cancer
- Suitable for research in neurological diseases
Apexbio Technology LLC Glimepiride 93479-97-1 1g
Glimepiride (CAS 93479-97-1) is a sulfonylurea compound widely used in research on type 2 diabetes It primarily acts by enhancing glucose uptake both in the presence and absence of insulin In cultured cells glimepiride (10 M) increases 2-deoxyglucose uptake to 186% of control and upregulates GLUT1 and GLUT4 expression to 164% and 148% of control respectively indicating insulin-independent mechanisms for stimulating cardiac glucose uptake In rodent models glimepiride administration reduced diabetes incidence by 23% in BB rats and decreased blood glucose HbA1c and plasma insulin levels in KK-Ay mice highlighting its utility for investigating glucose metabolism and diabetes pathophysiology
eMolecules 873-41-6 | 3,5,6-trichloro-1,2,4-triazine | Pharmablock | MFCD09033774 | 184.400 | C3Cl3N3 | 97.000 | Clc1nnc(Cl)c(Cl)n1 | 5g | 551253161
3,5,6-trichloro-1,2,4-triazine | Pharmablock | 873-41-6 | MFCD09033774 | 184.400 | C3Cl3N3 | 97.000 | Clc1nnc(Cl)c(Cl)n1 | 5g | 551253161
eMolecules 835619-41-5 | Medchem Express | Indeglitazar | 5mg | 446264614 | HY-14817 | MFCD18633304 | 389.42 | C19H19NO6S
Medchem Express | Indeglitazar | 5mg | 446264614 | HY-14817 | 835619-41-5 | MFCD18633304 | 389.420 | C19H19NO6S
Medchemexpress LLC HY-19977 5mg Medchemexpress, YU238259 CAS:1943733-16-1 Purity:>98%
Medchemexpress, HY-19977 5mg YU238259 CAS:1943733-16-1 YU238259 is an inhibitor of homology-dependent DNA repair (HDR), used for cancer research. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.