Benzenesulfonamides
Medchemexpress LLC Sildenafil impurity 3 | 1357931-55-5 | MFCD22683782 | 50mg
Sildenafil Impurity 3 is an impurity of Sildenafil (HY-15025)
Apexbio Technology LLC Benzenesulfonamide 98-10-2 100mg
Benzenesulfonamide (CAS 98-10-2) is an amide derivative of benzenesulfonic acid widely utilized as a synthetic intermediate for pharmaceuticals and other chemicals Mechanistically benzenesulfonamide derivatives have been investigated for their inhibitory activity against various human carbonic anhydrases (CAs) with certain 4-substituted diazo derivatives exhibiting strong binding affinity particularly for CA I and II isoforms as demonstrated by isothermal titration calorimetry and fluorescence-based thermal shift assays In in vivo models indole-based benzenesulfonamide derivatives show oral activity in rat and sheep models of airway inflammation attenuating physiological responses to antigenic or cholinergic challenge Benzenesulfonamide remains in preclinical evaluation
Apexbio Technology LLC Bosentan Hydrate, 500mg. Cas: 157212-55-0 MFCD: MFCD09751188. endothelin receptor antagonist
IC50: Inhibiting endothelin receptor A and B with an IC50 of 15.1 1.6 M in P388/dx cells.A sulfonamide-derived, competitive and specific endothelin receptor antagonist with a relatively higher affinity to the endothelin A receptor than endothelin B receptor. Other sizes are available. Please inqury us for quote.
Medchemexpress LLC Sildenafil impurity 1 | 1094598-75-0 | MFCD22683784; MFCD34755806 | 25mg
Sildenafil Impurity 1 is an impurity of Sildenafil (HY-15025)
![eMolecules 171599-83-0 | Sildenafil (citrate) | Medchem Express | MFCD09026931 | 666.700 | C28H38N6O11S | 98.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 | 50mg | 446264915](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000193304.jpg-250.jpg)
eMolecules 171599-83-0 | Sildenafil (citrate) | Medchem Express | MFCD09026931 | 666.700 | C28H38N6O11S | 98.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 | 50mg | 446264915
Sildenafil (citrate) | Medchem Express | 171599-83-0 | MFCD09026931 | 666.700 | C28H38N6O11S | 98.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O.CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 | 50mg | 446264915
![Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 | C17H22N2O5S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248189.png-250.jpg)
Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 | C17H22N2O5S2 | 10 MG
TMI-1 is a small-molecule inhibitor of TNF-α converting enzyme (TACE/ADAM17) with activity against several ADAM and matrix metalloproteinase (MMP) family proteases. It has demonstrated antiproliferative and pro-apoptotic effects in cancer cell models and can suppress TNF-α secretion and inflammatory responses in preclinical studies. Supplied as a high-purity solid for research use.
- Inhibits TACE (ADAM17) and multiple MMPs with low-nanomolar potency.
- Demonstrates antiproliferative and apoptosis-inducing activity in cellular models.
- Reduces TNF-α secretion and inflammatory markers in preclinical studies.
- High purity solid suitable for biochemical and cellular assays.
- Available in small mass packs for research applications.
![eMolecules 1014613-05-8 | 1-(benzenesulfonyl)-4-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine | MFCD13191645 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502136296.JPG-250.jpg)
eMolecules 1014613-05-8 | 1-(benzenesulfonyl)-4-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine | MFCD13191645 | 1g
ChemScene | 135-Triethylbenzene | 1g | 694122597 | CS-0046776 | 102-25-0 | MFCD00009261 | 162.276 | C12H18
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Accela Chembio Inc 4-ethylbenzenesulfonamide | 100g | 138-38-5 | MFCD01365828 | 97+% | Shelf Life: 1260 Days | Light Sensitive
4-ethylbenzenesulfonamide | 100g | 138-38-5 | MFCD01365828 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Medchemexpress LLC Sulfacetamide sodium monohydrate | 6209-17-2 | 99.8% | 100 G
Sulfacetamide sodium monohydrate is a sulfonamide antibiotic primarily used for research purposes. It demonstrates both antibacterial and antifungal activities, making it suitable for the study of various ocular infections.
- Can be used for the study of various ocular infections, including trachoma, blepharitis, conjunctivitis, corneal ulcer, pityriasis versicolor, and rosacea.
- Exhibits antifungal activity.
- Acts as a bacteriostatic agent against Gram-positive and Gram-negative bacteria.
- For research use only.
Accela Chembio Inc 4-fluoro-3-nitrobenzenesulfonamide | 5g | 406233-31-6 | MFCD08703185 | 97+% | Shelf Life: 1260 Days | Regular
4-fluoro-3-nitrobenzenesulfonamide | 5g | 406233-31-6 | MFCD08703185 | 97+% | Shelf Life: 1260 Days | Regular
Medchemexpress LLC HY-112438 5mg Medchemexpress, MF-094 CAS:2241025-68-1 Purity:>98%
Medchemexpress, HY-112438 5mg MF-094 CAS:2241025-68-1 MF-094 is a potent and selective USP30 inhibitor with an IC 50 of 120 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical Sildenafil Inhibitors
A PDE5 inhibitor (IC50s = 3.6 and 3 nM for PDE5 activity in isolated rabbit platelets and human corpus cavernosum, respectively); selective for PDE5 over PDE1 and PDE3 (IC50s = 0.26 and 65 μM, respectively); reverses glucose-induced decreases in ANG1 expression and reduction of capillary-like tube formation by mouse dermal endothelial cells in vitro; increases the number of functional blood vessels and regional blood flow in the sciatic nerve in a db/db mouse model of diabetic peripheral neuropathy; increases ICP/MAP ratio in castrated rats at 20 mg/kg per day; reduces cardiac arrest and resuscitation-induced increases in angiotensin II ACE, ACE2, and various angiotensin receptors and increases survival in a porcine model of ischemia/reperfusion injury
eMolecules 97-04-1 | ChemScene | 2-Chloro-5-sulfamoylbenzoic acid | 100mg | 761228608 | CS-0462903 | MFCD00036103 | 235.64 | C7H6ClNO4S
ChemScene | 2-Chloro-5-sulfamoylbenzoic acid | 100mg | 761228608 | CS-0462903 | 97-04-1 | MFCD00036103 | 235.640 | C7H6ClNO4S
AdipoGen Glimepiride (1 g)
Chemical. CAS: 93479-97-1. Formula: C24H34N4O5S. MW: 490.62. Glimepiride is a long-acting sulfonylurea antidiabetic agent inhibiting ATP-sensitive potassium (KATP) channels in pancreatic beta-cells, which leads to the release of insulin. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle suggest that Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase and stimulates glucose transporter 1 and 4 (GLUT1/4) expression. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway and exhibits neuroprotective benefit, decreasing expression and activity of BACE1 and amyloid-beta (Abeta) in neurons in a PPARgamma-dependent manner.
