Benzenesulfonamides
Medchemexpress LLC Rac-osmi-1 | 2748153-92-4 | 96.5% | 5 MG
(Rac)-OSMI-1 is the racemic form of OSMI-1, a cell-permeable small-molecule inhibitor of O-GlcNAc transferase (OGT) used in biochemical and cell-based research to reduce protein O-GlcNAcylation.
- Cell-permeable OGT inhibitor with reported IC50 ≈ 2.7 μM.
- Suitable for cell-based assays and biochemical studies.
- Purity approximately 96.5% (manufacturer-stated).
- Molecular weight 563.64 g/mol; formula C28H25N3O6S2.
- Research-use only; not for clinical or human use.
Medchemexpress LLC HY-18054 5mg Medchemexpress, BVT 2733 CAS:376640-41-4 Purity:>98%
Medchemexpress, HY-18054 5mg BVT 2733 CAS:376640-41-4 BVT 2733 is a potent, selective, and orally active non-steroidal 11β-hydroxydehydrogenase 1 (11β-HSD1) inhibitor. BVT 2733 is potently against the mouse enzyme (IC50=96 nM) over the human enzyme (IC50=3341 nM). BVT 2733 has the potential for the study of arthritis and obesity related disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 26103-51-5 | 3-(Pyrrolidin-1-ylsulfonyl)pyridine | Combi-Blocks | MFCD09258659 | 212.270 | C9H12N2O2S | 98.000 | O=S(=O)(N1CCCC1)c1cccnc1 | 1g | 117548284
3-(Pyrrolidin-1-ylsulfonyl)pyridine | Combi-Blocks | 26103-51-5 | MFCD09258659 | 212.270 | C9H12N2O2S | 98.000 | O=S(=O)(N1CCCC1)c1cccnc1 | 1g | 117548284
Medchemexpress LLC Sildenafil (citrate) | 171599-83-0 | C28H38N6O11S | 5 G
Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It is intended for research use only.
- Potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM.
- Potentiates phosphorylation of ERK1/ERK2.
- Increases percentage of cells in S phase and cell proliferation.
- Enhances upregulation of ERK1/ERK2 phosphorylation induced by serotonin.
- Increases intracavernosal pressure (ICP) and ICP/BP in dog models.
- Reduces the number of TL+-cells and microglia/macrophages in ischemic models.
- Decreases flap necrosis by increasing growth factors (FGF and VEGF).
- Used in clinical trials for pulmonary arterial hypertension, erectile dysfunction, spinal cord injuries, pregnancy complication, cancer, and more.
Sigma Aldrich Fine Chemicals Biosciences Sildenafil citrate United States Pharmacopeia (USP) Reference Standard | 171599-83-0 | MFCD09026931 | 100MG
Sildenafil citrate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 666.7 | 171599-83-0 | MFCD09026931 | 100MG
Medchemexpress LLC HY-100892 5mg Medchemexpress, MX69 CAS:1005264-47-0 Purity:>98%
Medchemexpress, HY-100892 5mg MX69 CAS:1005264-47-0 MX69 is an inhibitor of MDM2/XIAP , used for cancer treatment. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 486422-58-6 | 4-(Piperidin-1-ylsulfonyl)phenylboronic acid | Combi-Blocks | MFCD06659850 | 269.120 | C11H16BNO4S | 98.000 | OB(O)c1ccc(cc1)S(=O)(=O)N1CCCCC1 | 1g | 117521176
4-(Piperidin-1-ylsulfonyl)phenylboronic acid | Combi-Blocks | 486422-58-6 | MFCD06659850 | 269.120 | C11H16BNO4S | 98.000 | OB(O)c1ccc(cc1)S(=O)(=O)N1CCCCC1 | 1g | 117521176
eMolecules 330161-87-0 | SU6656 | MFCD10565928 | 50mg
Ambeed | 3-(Furan-2-ylmethyl)-18-dimethyl-1H-purine-26(3H7H)-dione | 1mg | 598442356 | A389771 | 80288-49-9 | MFCD00153799 | 260.253 | C12H12N4O3
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Apexbio Technology LLC Glimepiride 93479-97-1 10mM (in 1mL DMSO)
Glimepiride (CAS 93479-97-1) is a sulfonylurea compound widely used in research on type 2 diabetes It primarily acts by enhancing glucose uptake both in the presence and absence of insulin In cultured cells glimepiride (10 M) increases 2-deoxyglucose uptake to 186% of control and upregulates GLUT1 and GLUT4 expression to 164% and 148% of control respectively indicating insulin-independent mechanisms for stimulating cardiac glucose uptake In rodent models glimepiride administration reduced diabetes incidence by 23% in BB rats and decreased blood glucose HbA1c and plasma insulin levels in KK-Ay mice highlighting its utility for investigating glucose metabolism and diabetes pathophysiology
Medchemexpress LLC H-1152 dihydrochloride | 871543-07-6 | 99.1% | 392.34 g/mol | C16H23Cl2N3O2S | 10 MG
H-1152 dihydrochloride is a membrane-permeable, selective inhibitor of Rho-associated protein kinases (ROCK), reported with a Ki of 1.6 nM and an IC50 of 12 nM for ROCK2. Supplied as the dihydrochloride salt in solid form, it is intended for research use and offers formulation options for both in vitro and in vivo studies.
- Potent inhibition of ROCK family kinases (Ki = 1.6 nM; IC50 ROCK2 = 12 nM).
- Membrane-permeable for cellular assays.
- High purity suitable for research applications.
- Multiple solubility and formulation options for in vitro and in vivo use.
- Available in small solid quantities convenient for laboratory experiments.
Medchemexpress LLC Homo sildenafil | 642928-07-2 | MFCD09752148 | 99.3% | 488.60 | C23H32N6O4S | 5 MG
Homo sildenafil is a small-molecule analog of sildenafil that functions as a phosphodiesterase (PDE) inhibitor for research and analytical applications. The compound is supplied as a solid with molecular formula C23H32N6O4S and molecular weight 488.60, and is accompanied by analytical documentation for quality verification.
- Acts as a phosphodiesterase inhibitor for biochemical and pharmacological studies.
- High purity (99.3%), suitable for analytical applications.
- Provided as a solid for convenient handling and storage.
- Molecular formula C23H32N6O4S and molecular weight 488.60.
- Analytical documents available: COA, SDS, HNMR, LCMS.
Medchemexpress LLC HY-114361 10mg Medchemexpress, OSMI-4 CAS:2260791-14-6 Purity:>98%
Medchemexpress, HY-114361 10mg OSMI-4 CAS:2260791-14-6 OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC RQ-00203078 1254205-52-1 10mg
RQ-00203078 (CAS 1254205-52-1) is a selective antagonist of the transient receptor potential melastatin 8 (TRPM8) ion channel a member of the TRP melastatin subfamily implicated in cold-induced pain hypersensitivity and neuropathic pain including chemotherapy-induced peripheral neuropathy diabetic neuropathy migraine and overactive bladder In in vitro assays RQ-00203078 inhibits menthol-induced TRPM8-mediated calcium influx with IC50 values of 8 3 nM in human and 5 8 nM in rat models demonstrating high selectivity over other TRP channels In vivo oral administration suppresses icilin-evoked tremors in rats in a dose-dependent manner (ED50 0 65 mg/kg) The compound remains in preclinical development and serves as a valuable tool for investigating TRPM8-related pathophysiology and potential therapeutic interventions
eMolecules 2271358-65-5 | Medchem Express | UAMC-3203 hydrochloride | 5mg | 455326080 | HY-112909A | 508.12 | C25H38ClN5O2S
Ambeed | 14-Bis(2-methyl-1H-imidazol-1-yl)butane | 100mg | 602852056 | A443716 | 52550-63-7 | 218.304 | C12H18N4
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![eMolecules 880769-95-9 | 3-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine | Combi-Blocks | MFCD09839041 | 337.190 | C13H9BrN2O2S | 95.000 | Brc1cn(c2ncccc12)S(=O)(=O)c1ccccc1 | 25g | 482931900](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502190348.JPG-250.jpg)
eMolecules 880769-95-9 | 3-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine | Combi-Blocks | MFCD09839041 | 337.190 | C13H9BrN2O2S | 95.000 | Brc1cn(c2ncccc12)S(=O)(=O)c1ccccc1 | 25g | 482931900
3-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine | Combi-Blocks | 880769-95-9 | MFCD09839041 | 337.190 | C13H9BrN2O2S | 95.000 | Brc1cn(c2ncccc12)S(=O)(=O)c1ccccc1 | 25g | 482931900