Benzenesulfonamides
eMolecules 362519-49-1 | Medchem Express | ()-Ibipinabant | 5mg | 446264564 | HY-14791A | MFCD12912330 | 487.4 | C23H20Cl2N4O2S
Ambeed | Ethyl 5-methyl-134-thiadiazole-2-carboxylate | 100mg | 600845636 | A684498 | 869108-50-9 | MFCD03840446 | 172.200 | C6H8N2O2S
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Selleck Chemical LLC Indisulam-5mg
Indisulam (E7070), a sulfonamide anticancer agent, is a potent carbonic anhydrase (CA) inhibitor that inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Indisulam suppresses the expression of cyclin E and phosphorylation of CDK2, both of which are essential for the G1 to S transition.
Medchemexpress LLC FASN-IN-3 | 2097262-60-5 | 384.47 | 100 MG
FASN-IN-3 is a fatty acid synthase (FASN) inhibitor, extracted from patent US20170119786A1, compound 242A. It is intended for research use only.
- Reduces IL-1 beta secretion from human PBMC stimulated with LPS or LTA.
- Reduces IL-1 beta from LTA-stimulated monocytes.
- Shows slight reduction of IL-1 beta after LPS stimulation.
- Targets fatty acid synthase (FASN).
Medchemexpress LLC Darunavir Ethanolate | 635728-49-3 | 99.9% | 593.73 | 100 MG
Darunavir ethanolate (TMC114 Ethanolate) is a potent HIV protease inhibitor used to treat and prevent HIV/AIDS. Darunavir has a Ki of 1 nM for wild type HIV-1 protease. It is for research use only and not sold to patients. Darunavir is effective against wild-type and PI-resistant HIV, and has an oral bioavailability of 37%. It needs to be combined with ritonavir, which increases the bioavailability to 82%.
- Potent HIV protease inhibitor
- Active against HIV-1 clinical isolates
- Forms hydrogen bonds with conserved main-chain atoms of Asp29 and Asp30 of the protease
- Greater potency than saquinavir, amprenavir, nelfinavir, indinavir, lopinavir, and ritonavir in an in vitro study
- Effective against wild-type and PI-resistant HIV
- Oral bioavailability increased to 82% when combined with ritonavir
Selleck Chemical LLC Saccharin S4819-25mg
Saccharin (Benzoic sulfimide O-Sulfobenzimide O-Benzoic sulfimide Saccharimide) is an artificial sweetener with effectively no food energy
eMolecules 81453-98-7 | 3-Acetyl-1-(phenylsulfonyl)pyrrole | MFCD00067752 | 5g
Combi-Blocks | 3-Acetyl-1-(phenylsulfonyl)pyrrole | 5g | 415502051 | QF-2049 | 98.000 | 81453-98-7 | MFCD00067752 | 249.280 | C12H11NO3S
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Cayman Chemical trns-carboxy GlImepIrIde 1mg
A metabolite of glimepiride; formed from glimepiride in a two-step process mediated by CYP2C9 and cytosolic enzymes
Medchemexpress LLC Sildenafil | 139755-83-2 | C22H30N6O4S | 200 MG
Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It demonstrates various cellular and in vivo activities, making it suitable for a range of research applications. This product is for research use only.
- Potent PDE5 inhibitor with an IC50 of 5.22 nM
- Inhibits human recombinant PDE5A1
- Potentiates ERK1/ERK2 phosphorylation
- Increases cell proliferation in S phase
- Significantly increases intracavernosal pressure (ICP) in dog models
- Reduces number of TL+-cells and microglia/macrophages in vivo
- Decreases flap necrosis in animal models by enhancing growth factor secretion
eMolecules 133745-75-2 | N-Fluorobenzenesulfonimide | Oakwood Chemicals | MFCD00144885 | 315.330 | C12H10FNO4S2 | 98.000 | FN(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 | 25g | 480105677
N-Fluorobenzenesulfonimide | Oakwood Chemicals | 133745-75-2 | MFCD00144885 | 315.330 | C12H10FNO4S2 | 98.000 | FN(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 | 25g | 480105677