Benzenesulfonamides
Medchemexpress LLC HY-100198 1mg Medchemexpress, PI4KIIIbeta-IN-10 CAS:1881233-39-1 Purity:>98%
Medchemexpress, HY-100198 1mg PI4KIIIbeta-IN-10 CAS:1881233-39-1 PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC 50 of 3.6 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC LPA2 antagonist 2 | 36840-10-5 | 95.0% | 380.35 | 10 MG
LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM. It demonstrates high selectivity, being >480-fold more selective than LPA3 (IC50 of 13.85 μM), and inhibits LPA1 with an Imax of 59.0% at 30 μM. This chemical is intended for research use only.
- Selective antagonist for LPA2.
- Inhibits LPA1.
- Targets LPL receptor.
- Involved in the GPCR/G protein pathway.
- Suitable for in vitro research.
- Store at -20°C for powder and -80°C for solvent.
![eMolecules 7411-23-6 | 3,5-DIBROMO-1H-1,2,4-TRIAZOLE | AstaTech | MFCD00487260 | 226.859 | C2HBr2N3 | 95.000 | Brc1n[nH]c(Br)n1 | 25g | 233626202](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
eMolecules 7411-23-6 | 3,5-DIBROMO-1H-1,2,4-TRIAZOLE | AstaTech | MFCD00487260 | 226.859 | C2HBr2N3 | 95.000 | Brc1n[nH]c(Br)n1 | 25g | 233626202
3,5-DIBROMO-1H-1,2,4-TRIAZOLE | AstaTech | 7411-23-6 | MFCD00487260 | 226.859 | C2HBr2N3 | 95.000 | Brc1n[nH]c(Br)n1 | 25g | 233626202
Selleck Chemical LLC KN-92 phosphate
KN-92 is an inactive derivative of KN-93 the selective inhibitor of Ca2 /calmodulin-dependent kinase type II (CaMKII)
Medchemexpress LLC N-desmethyl sildenafil | 139755-82-1 | MFCD00908398 | 99.5% | 460.55 g/mol | C21H28N6O4S | 100 MG
N-desmethyl sildenafil is the primary human metabolite of sildenafil and is supplied as a high-purity reference standard for research use in studies of phosphodiesterase type 5 (PDE5) metabolism and pharmacology. It is intended for analytical, metabolic, and assay development applications.
- High purity suitable for analytical reference (reported 99.5%).
- Used as a metabolite reference in pharmacokinetic and metabolic pathway studies.
- Stable solid form for storage and handling in laboratory settings.
- Compatible with LC-MS and related analytical methods.
- Provided as a 100 MG sample for benchtop experiments and assay calibration.
Medchemexpress LLC Sildenafil (citrate) | 171599-83-0 | C28H38N6O11S | 1 ML
Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. It is intended for research use only and is available in solid form or as a 10 mM solution in DMSO. Various quantities are available, and other forms like Sildenafil and deuterated versions also exist.
- Potent PDE5 inhibitor with an IC50 of 5.22 nM.
- Suitable for research purposes.
- Available in various forms and quantities, including solid or 10 mM solution in DMSO.
- Cited in numerous top scientific publications.
- Biological activity demonstrated in vitro and in vivo.
- Associated with numerous clinical trials for various conditions.
Medchemexpress LLC HY-111941 5mg Medchemexpress, GSK8612 CAS:2361659-62-1 Purity:>98%
Medchemexpress, HY-111941 5mg GSK8612 CAS:2361659-62-1 GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC 50 of 6.8 for recombinant TBK1 [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 857290-04-1 | Medchem Express | PF-915275 | 5mg | 446268868 | HY-18056 | MFCD12828758 | 350.4 | C18H14N4O2S
Medchem Express | PF-915275 | 5mg | 446268868 | HY-18056 | 857290-04-1 | MFCD12828758 | 350.400 | C18H14N4O2S
eMolecules 2748153-92-4 | Medchem Express | (Rac)-OSMI-1 | 5mg | 633696996 | HY-119738A | 563.64 | C28H25N3O6S2
ChemScene | 2-((Trimethylsilyl)ethynyl)pyridin-4-amine | 100mg | 781209716 | CS-0454742 | 667932-22-1 | MFCD27987137 | 190.321 | C10H14N2Si
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Apexbio Technology LLC Sildenafil 139755-83-2 200mg
Sildenafil (CAS 139755-83-2) is a small molecule inhibitor of phosphodiesterase type 5 (PDE5) By selectively blocking PDE5 activity sildenafil increases intracellular levels of cyclic guanosine monophosphate (cGMP) thereby modulating smooth muscle relaxation The compound exhibits an IC50 value of 5 22 nM against PDE5 indicating high potency in enzymatic assays Sildenafil is widely utilized in biomedical research to study cGMP signaling pathways and vascular smooth muscle physiology as well as to evaluate mechanisms underlying vasodilation and related pathophysiological conditions
Medchemexpress LLC N-desmethyl sildenafil | 139755-82-1 | MFCD00908398 | 99.5% | 460.55 | C21H28N6O4S | 25 MG
N-desmethyl sildenafil is the primary N-desmethylated metabolite of sildenafil supplied as an analytical reference standard for laboratory research. It is available in solid and solution formats for analytical applications and quality control, and is intended for research use only (not for human or clinical use).
- Provided as solid and solution formats for flexibility in assays.
- High purity (99.5%) suitable for analytical and reference standard use.
- Molecular formula C21H28N6O4S; molecular weight 460.55.
- Used in pharmacokinetic, metabolite identification, and analytical method development studies.
- Available in multiple small-scale pack sizes for laboratory workflows.
eMolecules 181885-68-7 | Medchem Express | LDS-751 | 5mg | 446274362 | HY-D0996 | MFCD00467069 | 471.98 | C25H30ClN3O4
ChemScene | Methyl 4-aminothiazole-5-carboxylate | 100mg | 536835341 | CS-D1071 | 278183-10-1 | MFCD09033876 | 158.180 | C5H6N2O2S
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Medchemexpress LLC GSK8612 | 2361659-62-1 | 99.6% | 520.33 | 100 MG
GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1. It is intended for research use only and not for sale to patients. In vitro, GSK8612 inhibits toll-like receptor (TLR)3-induced IRF3 phosphorylation in Ramos cells and type I IFN secretion in primary human mononuclear cells. In THP1 cells, it inhibits the secretion of IFNβ in response to dsDNA and cGAMP, the natural ligand for STING.
- Highly selective and potent tank-binding kinase-1 (TBK1) inhibitor.
- pIC50 of 6.8 for recombinant TBK1.
- Inhibits TLR3-induced IRF3 phosphorylation in Ramos cells.
- Inhibits type I IFN secretion in primary human mononuclear cells.
- Inhibits secretion of IFNβ in response to dsDNA and cGAMP in THP1 cells.