Benzenesulfonamides
eMolecules 565178-12-3 | 1-(Thien-2-ylsulfonyl)piperazine | Combi-Blocks | MFCD03987297 | 232.320 | C8H12N2O2S2 | 98.000 | O=S(=O)(N1CCNCC1)c1cccs1 | 1g | 117569182
1-(Thien-2-ylsulfonyl)piperazine | Combi-Blocks | 565178-12-3 | MFCD03987297 | 232.320 | C8H12N2O2S2 | 98.000 | O=S(=O)(N1CCNCC1)c1cccs1 | 1g | 117569182
eMolecules 690662-91-0 | N-Benzyl 3-boronobenzenesulfonamide | Combi-Blocks | MFCD07783857 | 291.130 | C13H14BNO4S | 98.000 | OB(O)c1cccc(c1)S(=O)(=O)NCc1ccccc1 | 1g | 117521522
N-Benzyl 3-boronobenzenesulfonamide | Combi-Blocks | 690662-91-0 | MFCD07783857 | 291.130 | C13H14BNO4S | 98.000 | OB(O)c1cccc(c1)S(=O)(=O)NCc1ccccc1 | 1g | 117521522
![eMolecules 2158-14-7 | 4-Acetamidobenzenesulfonyl Azide | Accela ChemBio (ASD) | MFCD00029626 | 240.240 | C8H8N4O3S | 97.000 | CC(=O)Nc1ccc(cc1)S(=O)(=O)N=[N+]=[N-] | 10g | 444748600](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000491665.jpg-250.jpg)
eMolecules 2158-14-7 | 4-Acetamidobenzenesulfonyl Azide | Accela ChemBio (ASD) | MFCD00029626 | 240.240 | C8H8N4O3S | 97.000 | CC(=O)Nc1ccc(cc1)S(=O)(=O)N=[N+]=[N-] | 10g | 444748600
4-Acetamidobenzenesulfonyl Azide | Accela ChemBio (ASD) | 2158-14-7 | MFCD00029626 | 240.240 | C8H8N4O3S | 97.000 | CC(=O)Nc1ccc(cc1)S(=O)(=O)N=[N+]=[N-] | 10g | 444748600
Selleck Chemical LLC Hydroxyhexamide
Hydroxyhexamide is a pharmacologically active metabolite of acetohexamide which is a sulfonylurea hypoglycemic agent
Medchemexpress LLC Probenecid | 57-66-9 | 99.94% | 500 MG
Probenecid is a potent and selective agonist for transient receptor potential vanilloid 2 (TRPV2) channels and acts as an inhibitor of pannexin 1 channels. It is widely utilized in research to study various biological processes.
- Potent and selective agonist of TRPV2 channels
- Inhibits pannexin 1 channels
- Efficiently inhibits ATP-dependent active vesicular NEM-GS uptake by MRP1 and MRP2
- Inhibitor of hTAS2R16, hTAS2R38, and hTAS2R43 bitter taste receptors
- Enhances cellular signals in GPCR calcium mobilization assays
- Increases contractility (ejection fraction, EF) in WT mice
- Involved in numerous clinical trials for various conditions
Medchemexpress LLC IACS-13909 | 2160546-07-4 | 99.97% | 377.27 | 25 MG
IACS-13909 is a selective, potent, and orally active SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM. It demonstrates greater selectivity for SHP2 compared to other phosphatases, including SHP1. This compound exhibits antitumor activities and effectively suppresses MAPK pathway signaling in receptor tyrosine kinase (RTK)-dependent cancers.
- Selective, potent, and orally active SHP2 allosteric inhibitor
- Greater selectivity for SHP2 compared to other phosphatases
- Exhibits antitumor activities
- Suppresses MAPK pathway signaling in RTK-dependent cancers
Medchemexpress LLC Sulfacetamide sodium | 127-56-0 | 99.7% | 5 G
Sulfacetamide sodium is a sulfonamide antibiotic for studying ocular infections. It exhibits antifungal and antibacterial properties, effective against both Gram-positive and Gram-negative bacteria.
- Utilized for various ocular infections such as trachoma, blepharitis, and conjunctivitis
- Functions as an antifungal agent through a CYP51A1-independent mechanism
- Acts as a bacteriostatic agent with activity against a broad spectrum of bacteria
Cayman Chemical SIldenafIl Chlorosulfonyl 5g
An intermediate in the synthesis of sildenafil; a potential impurity found in commercial preparations of sildenafil
Medchemexpress LLC Glimepiride sulfonamide | 119018-29-0 | MFCD02955393 | 98.0% | 351.43 g/mol | C16H21N3O4S | 100 MG
Glimepiride sulfonamide is a chemical intermediate used in the synthesis of the antidiabetic agent glimepiride. It is supplied as an off-white to white solid powder and as DMSO solutions for research and analytical use. The compound has a molecular weight of approximately 351.4 g/mol and chemical formula C16H21N3O4S, and typical analytical standards are supplied at ~98% purity.
- Used as an intermediate for the synthesis of glimepiride and related compounds.
- Available as a solid powder and as a DMSO solution (10 mM, 1 mL).
- Physical form: off-white to white solid powder suitable for synthetic and analytical applications.
- Molecular weight: ~351.4 g/mol; chemical formula: C16H21N3O4S.
- Storage: powder at cold temperatures for long-term stability; in solvent, store at ultracold temperatures for short-term stability.
- Analytical standard available with typical purity around 98%.
Medchemexpress LLC XMU-MP-3 | 2031152-08-4 | 95.78% | 536.55 | 100 MG
XMU-MP-3 is a potent non-covalent BTK inhibitor with IC50s of 10.7 nM for BTK WT and 17.0 nM for BTK C481S mutation in the presence of 10 μM ATP. It also induces apoptosis. This product is for research use only.
- Potent non-covalent BTK inhibitor
- Induces apoptosis
- Inhibits BTK-transformed Ba/F3 cell proliferation
- Maintains inhibitory potency against BTK(C481S)-Ba/F3 cells
- Substantially suppresses tumor growth in mouse xenograft models
- Significantly reduces tumor size without affecting animal weights
Apexbio Technology LLC Sildenafil mesylate 1308285-21-3 25mg
Sildenafil mesylate (CAS 1308285-21-3) is a potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) exhibiting an IC50 of 3 5 nM By inhibiting PDE5-mediated cGMP hydrolysis it enhances endogenous cGMP levels particularly within corpus cavernosum tissue In vitro sildenafil mesylate reversibly potentiates relaxation responses in precontracted corpus cavernosum strips following sodium nitroprusside exposure or electrical stimulation and increases intracellular cGMP in treated smooth muscle cells In vivo it augments erectile responses in anesthetized canine models This compound is widely used for studying PDE5-related signaling pathways and pharmacological modulation in erectile and vascular function research
Medchemexpress LLC HY-14571 10mg Medchemexpress, E7820 CAS:289483-69-8 Purity:>98%
Medchemexpress, HY-14571 10mg E7820 CAS:289483-69-8 E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC50 of 0.11 μg/ml. E7820 modulates α-1, α-2, α-3, and α-5 integrin mRNA expression. Antiangiogenic and antitumor activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Methylenephosphonic acid CD73 inhibitor | 2216764-29-1 | 99.2% | 463.81 g·mol⁻¹ | C16H23ClN5O7P | 5 MG
CD73-IN-4 is a potent, selective methylenephosphonic acid inhibitor of ecto-5'-nucleotidase (CD73) with low-nanomolar activity against human CD73. It is supplied as a research reagent for biochemical and cell-based studies, with reported high purity and multiple pack size options. Molecular formula C16H23ClN5O7P; molecular weight 463.81 g·mol⁻¹.