Cyclohexylphenols
Medchemexpress LLC EZM0414 | 2411748-50-8 | 99.1% | C22H29FN4O2 | 50 MG
EZM0414 is a potent, selective, and orally bioavailable inhibitor of SETD2. It is used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma.
- Potent, selective, orally bioavailable inhibitor of SETD2
- IC50 of 18 nM in SETD2 biochemical assay
- IC50 of 34 nM in cellular assay
- Inhibits proliferation of MM and DLBCL cell lines
- Well-tolerated and inhibits tumor growth in xenograft models
- Almost 100% oral bioavailability in rats and mice
Medchemexpress LLC HY-111387 5mg Medchemexpress, IDF-11774 CAS:1429054-28-3 Purity:>98%
Medchemexpress, HY-111387 5mg IDF-11774 CAS:1429054-28-3 IDF-11774 is a novel hypoxia-inducible factor α (HIFα)-1 inhibitor with an IC50 of 3.65 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 122520-74-5 | 2-Cyano-3-(4-fluorophenyl)prop-2-enoic acid | AA Blocks LLC191.161 | C10H6FNO2 | 0.000 | OC(=O)C(=Cc1ccc(F)cc1)C#N | 250mg | 437108324
2-Cyano-3-(4-fluorophenyl)prop-2-enoic acid | AA Blocks LLC | 122520-74-5191.161 | C10H6FNO2 | 0.000 | OC(=O)C(=Cc1ccc(F)cc1)C#N | 250mg | 437108324
eMolecules 50-27-1 | Medchem Express | Estriol | 100mg | 446272675 | HY-B0412 | MFCD00003691 | 288.387 | C18H24O3
Medchem Express | Estriol | 100mg | 446272675 | HY-B0412 | 50-27-1 | MFCD00003691 | 288.387 | C18H24O3
Medchemexpress LLC Enavogliflozin | 1415472-28-4 | 98.4% | 446.92 | 10 MG
Enavogliflozin is an antidiabetic agent that acts as an orally active and selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor. This compound is considered best-in-class for its properties.
- Antidiabetic agent
- Orally active
- Selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor
Medchemexpress LLC HY-13636 100mg Medchemexpress, Fulvestrant CAS:129453-61-8 Purity:>98%
Medchemexpress, HY-13636 100mg Fulvestrant CAS:129453-61-8 Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 32210-23-4 | 4-tert-Butylcyclohexyl acetate | Combi-Blocks, Inc. | MFCD00019354 | 198.306 | C12H22O2 | 96.000 | CC(=O)OC1CCC(CC1)C(C)(C)C | 25g | 603138967
4-tert-Butylcyclohexyl acetate | Combi-Blocks, Inc. | 32210-23-4 | MFCD00019354 | 198.306 | C12H22O2 | 96.000 | CC(=O)OC1CCC(CC1)C(C)(C)C | 25g | 603138967
Medchemexpress LLC Estradiol-d4 | 66789-03-5 | 99.6% | 1 MG
Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. It upregulates IL-6 expression through the estrogen receptor beta (ERβ) pathway.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements
- Deuteration affects the pharmacokinetic and metabolic profiles of drugs
- Applicable in cancer research, metabolic or endocrine disease, and endocrinology
Medchemexpress LLC (SP-4-2)-diamminetrans-dioxo(tetrahydro-2H-pyran-4,4-diyl)dihydrogen phosphate platinum | 1339960-28-9 | 95.0% | 485.23 | 100 MG
Imifoplatin (PT-112) is a platinum-based active molecule, categorized within the phosphaplatins family. It is known for its ability to induce apoptosis and demonstrates significant antitumor activity. This compound has been investigated for its potential in treating various cancers, showing promising results in both *in vitro* and *in vivo* studies, particularly in inhibiting proliferation and inducing apoptosis in cancer cell lines.
- Induces apoptosis.
- Exhibits antitumor activity.
- Shows dose-dependent proliferation inhibition in cancer cells.
- Significantly increases mitochondrial reactive oxygen species (mtROS).
- Demonstrates potent antitumor immune effects in xenograft models.
- Shows synergistic antitumor effects when combined with immune checkpoint blockers.
eMolecules 474-86-2 | Medchem Express | Equilin | 10mg | 518571293 | HY-B1176 | MFCD00046223 | 268.356 | C18H20O2
Medchem Express | Neuropeptide FF | 1mg | 642185143 | HY-P1248 | 99566-27-5 | MFCD00076704 | 1081.290 | C54H76N14O10
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Medchemexpress LLC Mauritianin | 109008-28-8 | MFCD32197360 | 99.8% | 740.66 g·mol⁻¹ | C33H40O19 | 10 MG
Mauritianin is an orally active kaempferol glycoside isolated from the flowers and leaves of Acalypha indica. It is reported to inhibit topoisomerase I and is provided as a high-purity research reagent with supporting product documentation and safety data.
- Orally active kaempferol glycoside with reported biological activity.
- High purity: 99.8% as listed by the supplier.
- Chemical formula C33H40O19 and molecular weight 740.66 g·mol⁻¹.
- Supplied as a solid in small research quantities (example: 10 mg).
- Product data sheet and safety data sheet available for handling and characterization.
- Suitable for research into flavonoid bioactivity and topoisomerase-related mechanisms.
Medchemexpress LLC Dihydroresveratrol | 58436-28-5 | MFCD25973128 | 99.6% | 230.26 g/mol | C14H14O3 | 10 MG
Dihydroresveratrol is a research-grade small-molecule phytoestrogen and estrogen receptor/ERR modulator supplied as a high-purity solid for biochemical and cellular research applications.
- High purity suitable for analytical and biological studies.
- Provided as a white to off-white solid for easy handling and storage.
- Suitable for receptor modulation and biochemical assay applications.
- Available in small milligram pack sizes for research use.
- Stable under recommended storage conditions when protected from light.
Medchemexpress LLC Parishin | 62499-28-9 | MFCD22125006 | 98.9% | 996.91 | C45H56O25 | 10 MG
Parishin is a phenolic glucoside isolated from Gastrodia elata that exhibits anti-aging activity in yeast via modulation of the Sir2/Uth1/TOR signaling pathway. It is supplied as a high-purity solid with recommended solvent formulations and storage conditions for research applications.
- High purity (98.92%)
- Off-white to light yellow solid
- Available as solid and as 10 mM DMSO solution for in vitro use
- Recommended storage: 4°C (solid); in solvent: -80°C (6 months), -20°C (1 month)
- Intended for research use only
Aobchem 1-(2-(Ethylthio)phenyl)cyclohexanol | 95% | C14H20OS | 1g
1-(2-(Ethylthio)phenyl)cyclohexanol | 95% | C14H20OS | 1g
Aobchem 1-(2-(Ethylthio)phenyl)cyclohexanol | 95% | C14H20OS | 500mg
1-(2-(Ethylthio)phenyl)cyclohexanol | 95% | C14H20OS | 500mg