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Filtered Search Results
Selleck Chemical LLC acalisib
Acalisib (GS-9820 CAL-120) is a highly selective and potent p110 inhibitor (IC50 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK
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Chemscene ChemScene | 2-(2,3,6-Trifluorophenyl)acetic acid | 5G | CS-W015908 | 0.97 | 114152-23-7| MFCD00061217 | 190.12
ChemScene | 2-(2,3,6-Trifluorophenyl)acetic acid | 5G | CS-W015908 | 0.97 | 114152-23-7| MFCD00061217 | 190.12
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eMolecules 53209-19-1 | 4-Nitro-1,2-phenylenediamine monohydrochloride | Combi-Blocks | MFCD00043273 | 189.600 | C6H8ClN3O2 | 95.000 | Cl.Nc1ccc(cc1N)[N+]([O-])=O | 5g | 495746633
4-Nitro-1,2-phenylenediamine monohydrochloride | Combi-Blocks | 53209-19-1 | MFCD00043273 | 189.600 | C6H8ClN3O2 | 95.000 | Cl.Nc1ccc(cc1N)[N+]([O-])=O | 5g | 495746633
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Chemscene ChemScene | 2,6-Dichloro-4-fluoroaniline | 25G | CS-W017244 | 0.98 | 344-19-4| MFCD00142845 | 180.009
ChemScene | 2,6-Dichloro-4-fluoroaniline | 25G | CS-W017244 | 0.98 | 344-19-4| MFCD00142845 | 180.009
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eMolecules 484049-04-9 | Medchem Express | DPH | 10mg | 446260703 | HY-12070 | MFCD03268950 | 336.326 | C18H13FN4O2
Medchem Express | ()-2-Methylbutyryl-L-carnitine-d3 (chloride) | 1mg | 721434682 | HY-132958S | | 284.800 | C12H24ClNO4
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Medchemexpress LLC 1H-Indole-6-carboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]- | 2259624-71-8 | 98.3% | 490.88 | 100 MG
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STING agonist-12 (Compound 53) is a potent, orally active human STING activator with an EC50 of 185 nM. It exhibits excellent pan-polymorph activity across a panel of STING proteins in HEK293T cells, specifically 92%, 107%, and 92% against R232, H232, and HAQ, respectively. Notably, it is not active at mouse STING. In vivo, the compound is well-absorbed with a short terminal half-life.
- Potent, orally active human STING activator
- Shows excellent pan-polymorph activity across STING proteins in HEK293T cells
- Not active at mouse STING
- Well-absorbed with a short terminal half-life in vivo
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Medchemexpress LLC Gamma-secretase modulator 1 | 1172637-87-4 | 98.0% | 416.54 g/mol | C24H24N4OS | 50 MG
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Gamma-secretase modulator 1 is a small-molecule research reagent that modulates γ-secretase activity to alter amyloid-β peptide production. It is supplied as a solid for preclinical laboratory studies and intended for research use only; not for diagnostic or therapeutic use.
- Modulates γ-secretase activity to reduce Aβ42 production.
- Suitable for biochemical and cellular assays.
- High purity (98.0%) for reproducible results.
- Solid, white to off-white appearance for easy handling.
- Molecular weight 416.54 g/mol; formula C24H24N4OS.
- Powder stable at -20°C for long-term storage, 4°C for short-term storage.
- Supplied in a 50 MG quantity for small-scale studies.
- For research use only; not for human administration.
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eMolecules 85068-27-5 | Ambeed | 25-Difluorophenylacetic acid | 25g | 587278659 | A252300 | MFCD00010000 | 172.131 | C8H6F2O2
Ambeed | 25-Difluorophenylacetic acid | 25g | 587278659 | A252300 | 85068-27-5 | MFCD00010000 | 172.131 | C8H6F2O2
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Medchemexpress LLC Ccr2 antagonist 3 | 1380100-86-6 | 99.9% | 308.39 g·mol⁻1 | C17H25FN2O2 | 100 MG
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CCR2 antagonist 3 is a small-molecule chemokine receptor 2 (CCR2) antagonist supplied for laboratory research. It is intended for in vitro and cellular studies to probe CCR2-mediated signaling and inflammation pathways. For research use only; not for human or clinical use.
- High purity (99.9%) suitable for biochemical and cell-based assays.
- Molecular weight 308.39 g·mol⁻1 and formula C17H25FN2O2.
- Available as solid quantities and as a 10 mM solution in DMSO for convenient dosing.
- Recommended storage conditions provided to preserve compound stability.
- Useful tool compound for studying CCR2-related inflammatory responses.
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Selleck Chemical LLC Bulleyaconi cine A S3907-25mg
Bulleyaconi cine A (Bulleyaconitine A BLA) is an active ingredient of Aconitum bulleyanum plants and classified as an aconitine-like alkaloid It is a potent use-dependent blocker for both Nav1 7 and Nav1 8 Na currents
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Medchemexpress LLC Quinazolin-4-ylthiazol-2-ylamine | 404828-14-4 | 98.8% | 301.35 g/mol | C18H15N5 | 5 MG
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GSK-3 Inhibitor XIII is a potent, ATP-competitive small-molecule inhibitor of glycogen synthase kinase-3 (GSK-3) with a reported Ki of 24 nM. Supplied as a high-purity solid, it is intended for biochemical kinase assays and cellular studies of GSK-3 signaling and preclinical research.
- Potent ATP-competitive GSK-3 inhibitor (Ki 24 nM).
- High purity: 98.79% as supplied.
- Soluble in DMSO (100 mg/mL) and in formulation (10% DMSO/40% PEG300/5% Tween-80/45% saline) ≥ 2.5 mg/mL.
- Solid appearance: white to off-white powder, molecular weight 301.35 g/mol.
- Storage: powder -20°C (up to 3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Demonstrated antiproliferative activity across multiple cell lines in cellular assays.
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Selleck Chemical LLC Penfluridol-50mg
Penfluridol (TLP-607,R-16341) is a highly potent, first generation diphenylbutylpiperidine antipsychotic.
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Selleck Chemical LLC G1T38
G1T38 (Lerociclib) is a novel potent selective and orally bioavailable CDK4/6 inhibitor with IC50 values of 0 001 M 0 002 M and 0 028 M for CDK4 CDK6 and CDK9 respectively
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Enzo Life Sciences A1874 (10mg). CAS: 2064292-12-0
A1874 is a nutlin-based PROTAC targeting on BRD4, consist of a BRD4-ligand JQ1 linked to a MDM2 E3 ligase ligand RG7388. A1874 possesses dual function as it dose-dependently degraded its target BRD4, accompanied with the downregulation of c-MYC, as well as stabilization of P53 and upregulated P21 due to the efficient engagement of MDM2 by RG7388. Purity: ≥98%. Long Term Storage: -20°C.
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eMolecules 1315449-72-9 | Medchem Express | Osilodrostat (phosphate) | 5mg | 752823256 | HY-16276A | 325.236 | C13H13FN3O4P
ChemScene | tert-Butyl (5-amino-3-methylpyridin-2-yl)carbamate | 100mg | 788448995 | CS-0637392 | 1566524-62-6 | MFCD26032867 | 223.276 | C11H17N3O2
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