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Filtered Search Results
Medchemexpress LLC MCOPPB trihydrochloride | 1108147-88-1 | MFCD11840549 | 100.0% | 518.01 g·mol⁻1 | C26H43Cl3N4 | 5 MG
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MCOPPB trihydrochloride is a research-grade nociceptin/orphanin FQ (NOP) receptor agonist supplied as a trihydrochloride salt. It exhibits high affinity for the human NOP receptor (pKi ≈ 10.07) and is intended for use in pharmacological studies, available in both solid and ready-to-use solution formats.
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Medchemexpress LLC HY-14268 10mg Medchemexpress, Febuxostat CAS:144060-53-7 Purity:>98%
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Medchemexpress, HY-14268 10mg Febuxostat CAS:144060-53-7 Febuxostat (TEI 6720) is selective xanthine oxidase inhibitor with a Ki of 0.6 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 98959-89-8 | [4-(Ethanesulfonyl)phenyl]methanamine hydrochloride | MFCD28118402 | 1g
Ambeed | [4-(Ethanesulfonyl)phenyl]methanamine hydrochloride | 1g | 491675091 | A603648 | 98959-89-8 | MFCD28118402 | 235.730 | C9H14ClNO2S
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Medchemexpress LLC HY-111940 5mg Medchemexpress, LUT014 CAS:2274819-46-2 Purity:>98%
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Medchemexpress, HY-111940 5mg LUT014 CAS:2274819-46-2 LUT014 is a B-Raf inhibitor with an IC 50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC O-desmethyl galanthamine (sanguinine) | 60755-80-8 | MFCD07369289 | 99.7% | 273.33 g/mol | C16H19NO3 | 5 MG
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O-Desmethyl Galanthamine (Sanguinine) is a galanthamine-type alkaloid and an acetylcholinesterase (AChE) inhibitor used in neuropharmacology and biochemical research. It is provided as a high-purity powder and in DMSO solution formats for in vitro assays and mechanistic studies.
- High purity suitable for research-grade assays.
- Validated acetylcholinesterase inhibition; reported IC50 1.83 μM.
- Available as powder and DMSO solutions for flexible preparation.
- Stable when stored under recommended conditions for extended shelf life.
- Supplied in small quantities appropriate for screening and mechanistic work.
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eMolecules 396094-85-2 | Ambeed | (S)-4-Phenyl-2-(2-((R)-p-tolylsulfinyl)phenyl)-45-dihydrooxazole | 100mg | 633660209 | A1281561 | 361.46 | C22H19NO2S
Medchem Express | MGH-CP1 | 5mg | 736630859 | HY-139330 | 896657-58-2 | 368.500 | C20H24N4OS
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eMolecules 1446090-79-4 | Medchem Express | Lifirafenib | 5mg | 446269554 | HY-18957 | 478.431 | C25H17F3N4O3
Medchem Express | Loxapine | 100mg | 446268313 | HY-17390 | 1977-10-2 | MFCD00242836 | 327.810 | C18H18ClN3O
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eMolecules 1018678-50-6 | 2-(Difluoromethyl)benzaldehyde | ChemScene | MFCD16875639 | 156.132 | C8H6F2O | 96.000 | FC(F)c1ccccc1C=O | 100mg | 801476742
2-(Difluoromethyl)benzaldehyde | ChemScene | 1018678-50-6 | MFCD16875639 | 156.132 | C8H6F2O | 96.000 | FC(F)c1ccccc1C=O | 100mg | 801476742
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Medchemexpress LLC PRMT5-IN-1 hydrochloride | 99.5% | 455.29 | 10 MG
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PRMT5 IN-1 hydrochloride (compound 9), a hemiaminal, is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 11 nM for PRMT5/MEP50. It can be converted to aldehydes and react with C449 to form covalent adducts under physiological conditions. It is for research use only and not sold to patients.
- Potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor
- IC50 of 11 nM for PRMT5/MEP50
- Inhibits the PRMT5/MEP50 complex very rapidly with a Kinact of 0.068 min-1 and a good binding affinity (KI=55 nM)
- Inhibits the expression of cellular sDMA with an IC50 value of 0.012 μM in Granta-519 cells
- Inhibits cell proliferation in a dose-dependent manner with an IC50 value of 0.06 μM in Granta-519 cells
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Selleck Chemical LLC Icotinib (BPI-2009H) S2922-200mg
Icotinib (BPI-2009H) is a potent and specific EGFR inhibitor with IC50 of 5 nM including the EGFR EGFR(L858R) EGFR(L861Q) EGFR(T790M) and EGFR(T790M L858R)
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Medchemexpress LLC HY-119243 5mg Medchemexpress, LY2794193 CAS:2173037-97-1 Purity:>98%
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Medchemexpress, HY-119243 5mg LY2794193 CAS:2173037-97-1 LY2794193 is a highly potent and selective mGlu3 receptor agonist ( hmGlu3 K i =0.927 nM, EC 50 =0.47 nM; hmGlu2 K i =412 nM, EC 50 =47.5 nM) [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Eliglustat-d4 | 491833-29-5 | 98.0% | 408.57 | 1 MG
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Eliglustat-d4 is the deuterium-labeled version of Eliglustat. Eliglustat is a specific, potent, and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM. Deuteration, the incorporation of stable heavy isotopes of hydrogen, carbon, and other elements into drug molecules, is used as a tracer for quantitation during drug development and has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Specific, potent, and orally active glucocerebroside synthase inhibitor (IC50 of 24 nM).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Medchemexpress LLC HY-B1699 100mg Medchemexpress, Metrizoic acid CAS:1949-45-7 Purity:>98%
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Medchemexpress, HY-B1699 100mg Metrizoic acid CAS:1949-45-7 Metrizoic acid (Metrizoate) is an ionic contrast medium. Metrizoic acid (Metrizoate) shows high osmolality and has a risk of inducing allergic reactions[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-16568 50mg Medchemexpress, Irinotecan (hydrochloride trihydrate) CAS:136572-09-3 Purity:>98%
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Medchemexpress, HY-16568 50mg Irinotecan (hydrochloride trihydrate) CAS:136572-09-3 Irinotecan hydrochloride trihydrate ((+)-Irinotecan hydrochloride trihydrate) is a topoisomerase I inhibitor with antitumor activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 3-(4-methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone | 346640-08-2 | 98.0% | 378.45 | C15H10N2O4S3 | 25 MG
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CCF642 is a small-molecule protein disulfide isomerase (PDI) inhibitor reported to have an IC50 of 2.9 μM and to induce endoplasmic reticulum stress and apoptosis in multiple myeloma cells. The compound is supplied for research use with documented solubility and storage guidance for experimental workflows.
- Potent PDI inhibition with reported IC50 of 2.9 μM.
- Induces ER stress and apoptosis in multiple myeloma models.
- High solubility in DMSO for in vitro stock preparation.
- Stable as a powder under recommended cold storage conditions.
- Documented in vitro and in vivo formulation guidance for experimental use.
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