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Filtered Search Results
Medchemexpress LLC HY-100409 5mg Medchemexpress, PHCCC CAS:179068-02-1 Purity:>98%
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Medchemexpress, HY-100409 5mg PHCCC CAS:179068-02-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC MD2-TLR4-IN-1 | 2249801-12-3 | 98.2% | 10 MG
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MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex antagonist. It inhibits Lipopolysaccharides (LPS)-induced expression of TNF-α and IL-6 in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. This compound can be utilized for the study of acute lung injury (ALI).
- Exerts anti-inflammatory activity by inhibiting NF-κB in RAW264.7 macrophages.
- Directly binds to the MD2-TLR4 complex and disrupts MD2-TLR4 activation.
- Suppresses NF-κB p65 subunit nuclear levels in LPS-induced macrophages.
- Significantly inhibits macrophage infiltration and ameliorates histopathological changes in lung tissues.
- Effectively reduces airspace inflammation and amends pulmonary lobule tissue structure.
- Decreases LPS-induced myeloperoxidase (MPO) activity and serum TNF-α levels.
- Reduces mRNA levels of TNF-α, IL-6, IL-1β, IL-12, IL-33, and COX-2 in lung tissues.
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Medchemexpress LLC HY-109096 5mg Medchemexpress, Nidufexor CAS:1773489-72-7 Purity:>98%
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Medchemexpress, HY-109096 5mg Nidufexor CAS:1773489-72-7 Nidufexor is a farnesoid X receptor (FXR) agonist [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 3(2H)-Pyridazinone, 2,4-dimethyl-6-[1-[(1S)-1-phenylethyl]-6-(tetrahydropyran-4-yl)-1H-imidazo | 1660117-38-3 | 98.8% | 429.51 g/mol | C25H27N5O2 | 5 MG
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BRD4 Inhibitor-10 is a potent small-molecule inhibitor selective for the BD1 bromodomain of BRD4 (reported IC50 8 nM). Provided as a 5 mg solid research reagent, its chemical identifiers include CAS 1660117-38-3, formula C25H27N5O2, and molecular weight 429.51 g/mol. Supplier-reported purity is >98%.
- Potent BRD4-BD1 inhibition (IC50 8 nM).
- High purity suitable for biochemical and cellular assays.
- Well-defined small-molecule formula and molecular weight (C25H27N5O2; 429.51 g/mol).
- Supplied as a solid (5 mg) with solution formats available for immediate use.
- Intended for research use only; not for human or clinical use.
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Medchemexpress LLC HY-15079 5mg Medchemexpress, Talampanel CAS:161832-65-1 Purity:>98%
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Medchemexpress, HY-15079 5mg Talampanel CAS:161832-65-1 Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity. Talampanel (IVAX) has neuroprotective effects in rodent stroke models. Talampanel attenuates caspase-3 dependent apoptosis in mouse brain. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100454 50mg Medchemexpress, CGP 25454A CAS:104391-26-6 Purity:>98%
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Medchemexpress, HY-100454 50mg CGP 25454A CAS:104391-26-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10564 10mg Medchemexpress, Sarpogrelate (hydrochloride) CAS:135159-51-2 Purity:>98%
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Medchemexpress, HY-10564 10mg Sarpogrelate (HCl) CAS:135159-51-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 173334-57-1 | Aliskiren | MFCD09839018 | 50mg
Medchem Express | ICAM-1-IN-1 | 5mg | 446276030 | HY-U00003 | 251994-14-6 | 363.230 | C15H11BrN2O2S
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eMolecules 2243689-80-5 | Medchem Express | DM21 | 5mg | 694125054 | HY-139441 | 1215.85 | C58H83ClN8O16S
Ambeed | (4-Aminophenyl)(morpholino)methanone | 250mg | 525000707 | A110083 | 51207-86-4 | MFCD00158788 | 206.245 | C11H14N2O2
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Medchemexpress LLC 2-(4-Chloro-phenoxy)-phenylacetic acid | 25563-04-6 | 99.6% | 262.69 | 5 G
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2-(4-Chloro-phenoxy)-phenylacetic acid is a drug intermediate for the synthesis of various active compounds.
- Used for the synthesis of active compounds
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Medchemexpress LLC Phenoxybenzamine hydrochloride | 63-92-3 | 99.5% | 1 G
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Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist. It is primarily used in research for hypertension, particularly that caused by pheochromocytoma, and has also demonstrated antitumor activity.
- Inhibits proliferation of U251 and U87MG cells.
- Inhibits migration and invasion of U251 and U87MG cells.
- Activates LINGO-1 and inhibits the TrkB-Akt pathway.
- Prevents hippocampal cell death after oxygen glucose deprivation.
- Demonstrates anti-tumorigenic effect in nude mice with U87MG tumors.
- Exhibits neuroprotective properties in a rat model of severe traumatic brain injury.
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eMolecules 423148-46-3 | Medchem Express | SBC-115337 | 5mg | 649808990 | HY-141714 | MFCD02210564 | 473.488 | C29H19N3O4
ChemScene | Methyl 5-bromo-1H-pyrrole-2-carboxylate | 100mg | 536849766 | CS-W006646 | 934-07-6 | MFCD09801030 | 204.023 | C6H6BrNO2
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eMolecules 66067-44-5 | 3-Acetylbenzophenone | Toronto Research Chemicals | MFCD01662280 | 224.259 | C15H12O2 | 95.000 | CC(=O)c1cccc(c1)C(=O)c1ccccc1 | 100mg | 601588728
3-Acetylbenzophenone | Toronto Research Chemicals | 66067-44-5 | MFCD01662280 | 224.259 | C15H12O2 | 95.000 | CC(=O)c1cccc(c1)C(=O)c1ccccc1 | 100mg | 601588728
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Medchemexpress LLC Bambuterol-d9 hydrochloride | 1794810-59-5 | 99.9% | 412.96 | 5 MG
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Bambuterol-d9 hydrochloride is a deuterium-labeled form of Bambuterol, a long-acting beta-adrenoceptor agonist (LABA) and prodrug of terbutaline, primarily used in the treatment of asthma. This compound is also valuable as a tracer and internal standard for quantitative analysis in various spectroscopic methods.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC DSM705 hydrochloride | 2989908-08-7 | MFCD34676639 | 99.6% | 440.85 g/mol | C19H20ClF3N6O | 5 MG
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DSM705 hydrochloride is a pyrrole-based dihydroorotate dehydrogenase (DHODH) inhibitor developed as an orally active antimalarial compound. It shows nanomolar potency against Plasmodium DHODHs and parasites while exhibiting no inhibition of mammalian DHODHs. The substance is supplied as a hydrochloride salt, white to off-white solid, with molecular weight 440.85 g/mol and typical purity ~99.56%.
- Potent DHODH inhibitor with nanomolar activity against Plasmodium enzymes.
- Selective for parasite DHODH over mammalian DHODHs, reducing off-target effects.
- Suitable for in vitro and in vivo antimalarial research applications.
- High purity enables reliable biochemical and cellular assays.
- Available in small research quantities for early-stage studies.
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