Phenoxy compounds
1,3-Bis(2-hydroxyethoxy)benzene 98.0+%, TCI America™
CAS: 102-40-9 Molecular Formula: C10H14O4 Molecular Weight (g/mol): 198.22 MDL Number: MFCD00016566 InChI Key: IAXFZZHBFXRZMT-UHFFFAOYSA-N Synonym: Resorcinol Bis(beta-hydroxyethyl) Ether PubChem CID: 66885 IUPAC Name: 2-[3-(2-hydroxyethoxy)phenoxy]ethan-1-ol SMILES: OCCOC1=CC(OCCO)=CC=C1
Medchemexpress LLC HY-U00422 5mg Medchemexpress, K-756 CAS:130017-40-2 Purity:>98%
Medchemexpress, HY-U00422 5mg K-756 CAS:130017-40-2 K-756 is a direct and selective tankyrase ( TNKS ) inhibitor, which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 with IC 50 s of 31 and 36 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 2-(5-(Trifluoromethoxy)-1H-indol-3-yl)ethanamine hydrochloride | 1389313-40-9 | MFCD21090372 | 100mg
Oakwood Chemicals | 2-(5-(Trifluoromethoxy)-1H-indol-3-yl)ethanamine hydrochloride | 100mg | 480142624 | 091620 | | 1389313-40-9 | MFCD21090372 | 280.680 | C11H12ClF3N2O
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eMolecules Medchem Express / K-756 / 5mg / 415690724 / HY-U00422 / / 130017-40-2 / MFCD30537546 / 433.512 / C24H27N5O3
Medchem Express / K-756 / 5mg / 415690724 / HY-U00422 / / 130017-40-2 / MFCD30537546 / 433.512 / C24H27N5O3
Medchemexpress LLC PXS-5153A (monohydrochloride) | 2125956-82-1 | 99.6% | 438.95 | 50 MG
PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride could reduce crosslinks and ameliorate fibrosis.
- Exhibits an IC50 of <40 nM for LOXL2 across all mammalian species tested.
- Also inhibits human LOXL3 with an IC50 value of 63 nM.
- Is >40-fold selective for LOXL2 over both LOX and LOXL1 and >700-fold selective over other related amine oxidases.
- Is a fast acting inhibitor, with enzymatic activity almost entirely blocked within 15 minutes.
- Reduces crosslinks and ameliorates fibrosis.
Selleck Chemical LLC Amuvatinib (MP-470) S1244-2mg
Amuvatinib (MP-470 HPK 56) is a potent and multi-targeted inhibitor of c-Kit PDGFR and Flt3 with IC50 of 10 nM 40 nM and 81 nM respectively Amuvatinib suppresses c-MET and c-RET Amuvatinib is also active as a DNA repair protein Rad51 inhibitor with antineoplastic activity Phase 2
Medchemexpress LLC PXS-5153A monohydrochloride | 2125956-82-1 | 99.59% | 438.95 | 100 MG
PXS-5153A monohydrochloride is a potent, selective, orally active, and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor. It has an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. This compound can reduce crosslinks and ameliorate fibrosis.
- Potent, selective, orally active, and fast-acting LOXL2/LOXL3 inhibitor.
- IC50 of <40 nM for LOXL2 across all mammalian species.
- IC50 of 63 nM for human LOXL3.
- >40-fold selective for LOXL2 over LOX and LOXL1.
- >700-fold selective over other related amine oxidases.
- Fast-acting, with enzymatic activity almost entirely blocked within 15 minutes.
- Reduces crosslinks and ameliorates fibrosis.
Medchemexpress LLC HY-17386 200mg , Rosiglitazone BRL49653 CAS:122320-73-4 Purity:98%
Medchemexpress, HY-17386 200mg Rosiglitazone BRL49653 CAS:122320-73-4 Formula:C18H19N3O3S EC50: 30 nM (PPARγ1), 100 nM (PPARγ2) , 60 nM (PPARγ) , appr 30 nM (TRPC5) Kd: appr 40 nM (PPARγ) IC50: appr 22.5 μM (TRPM2) Purity:98% Rosiglitazone is a potent and selective activator of PPARγ , with EC 50 s of 30 nM, 100 nM and 60 nM for PPARγ1 , PPARγ2 , and PPARγ , respectively, and a K d of appr 40 nM for PPARγ ; Rosiglitazone is also an modulator of TRP channels , inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5). Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-114286A 5mg Medchemexpress, PXS-5153A (monohydrochloride) CAS: Purity:>98%
Medchemexpress, HY-114286A 5mg PXS-5153A (monoHCl) CAS: PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride could reduce crosslinks and ameliorates fibrosis. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-19835 5mg Medchemexpress, LY2922470 CAS:1423018-12-5 Purity:>98%
Medchemexpress, HY-19835 5mg LY2922470 CAS:1423018-12-5 LY2922470 is a potent, selective and orally available agonist of the G protein-coupled receptor 40 (GPR40), with EC50s of 7 nM, 1 nM and 3 nM for human GPR40, mouse GPR40 and rat GPR40, respectively. LY2922470 reduces glucose levels along with significant increases in insulin and GLP-1, is potential for the treatment of type 2 diabetes mellitus (T2DM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.