Styrenes
Apexbio Technology LLC NMS-873 1418013-75-8 10mM (in 1mL DMSO)
NMS-873 (CAS 1418013-75-8) is a selective inhibitor of the ATPase VCP/p97 demonstrating inhibitory activity with an IC50 value of 30 nM It targets wild-type VCP as well as VCPC522T mutants without disrupting VCP oligomerization NMS-873 exhibits selectivity against other AAA ATPases HSP90 and various kinases In tumor cell lines including HCT-116 treatment with NMS-873 induces accumulation of polyubiquitinated proteins and stabilization of cyclin E and Mcl-1 leading to altered cell-cycle distribution and reduced cell proliferation NMS-873 shows cytotoxicity across blood cancer and solid tumor cell models (IC50 values 0 08 2 M) supporting its utility in oncology research
TARGETMOL CHEMICALS INC AB-680 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AB-680 is a highly potent reversible and selective inhibitor of CD73 (an ectonucleotidase Ki 4.9 pM for hCD73) with anti-tumor activity displays >10000-fold selectivity over related ectonucleotidases CD39. purity: 97%
Sigma Aldrich Fine Chemicals Biosciences beta Galactosidase from Es
-Galactosidase is a tetramer consisting of four equal subunits of 135 000 each. It is a sulfhydryl containing enzyme with 19 cysteine residues per subunit.
eMolecules 27326-43-8 | 2-Vinylbenzoic acid | Apollo Scientific | MFCD02066273 | 148.161 | C9H8O2 | 95.000 | OC(=O)c1ccccc1C=C | 10g | 599358507
2-Vinylbenzoic acid | Apollo Scientific | 27326-43-8 | MFCD02066273 | 148.161 | C9H8O2 | 95.000 | OC(=O)c1ccccc1C=C | 10g | 599358507
Medchemexpress LLC Benzamide, 2-[[5-bromo-2-[[1-(methylsulfonyl)-4-piperidinyl)amino]-4-pyrimidinyl]amino]-6-fluoro- | 2488892-01-7 | C17H20BrFN6O3S | 25 MG
TMX-2039 is a pan-CDK inhibitor for both cell cycle CDKs (CDK1, CDK2, CDK4, CDK5, and CDK6) and transcriptional CDKs (CDK7 and CDK9). It acts as a ligand for target proteins for PROTACs, demonstrating IC50 values against CDK1 (2.6 nM), CDK2 (1.0 nM), CDK4 (52.1 nM), CDK5 (0.5 nM), CDK6 (35.0 nM), CDK7 (32.5 nM), and CDK9 (25 nM).
- Pan-CDK inhibitor
- Inhibits cell cycle CDKs
- Inhibits transcriptional CDKs
- Ligand for target protein for PROTACs
Cambridge Isotope Laboratories omega-Muricholic acid (unlabeled) 1 mg
omega-Muricholic acid (unlabeled) 1 mg
TARGETMOL CHEMICALS INC SACLOFEN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Saclofen is a sulfonic analog of the inhibitory neurotransmitter (gamma)-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50 7.8 uM).1 This compound can be used to determine the functional roles for the GABAB receptor as a mediator of slow inhibitory postsynaptic potentials in the brain. purity: 99%
Selleck Chemical LLC CPI-637
CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor with IC50 values of 0 03 M and 0 051 M for CBP and EP300 respectively in TR-FRET assay It is highly selective against other bromodomains displaying substantial biochemical activity only against BRD9
Medchemexpress LLC Mm-589 (racemic mixture) TFA | 99.8% | 686.72 g/mol | C30H45F3N8O7 | 25 MG
MM-589 (racemic mixture) TFA is the trifluoroacetic acid salt of a macrocyclic peptidomimetic inhibitor that targets the WDR5-MLL protein-protein interaction. Supplied as a high-purity solid for research use, it is intended for biochemical and cell-based assays; handle sealed and protected from moisture, and follow recommended cold storage conditions for stability.
- Potent inhibitor of WDR5-MLL protein-protein interaction.
- Supplied as a racemic TFA salt in solid powder form.
- High purity, 99.83%.
- Molecular weight 686.72 g/mol; formula C30H45F3N8O7.
- Available in small research package sizes, including 25 mg.
- Recommended storage: in solvent -80°C for up to 6 months, or -20°C for up to 1 month (sealed).
eMolecules 37125-92-1 | 2-Methyl-3-n,n-dimethylaminomethylindole | MFCD00022712 | 1g
Ambeed | (4-((3-Chloropropyl)carbamoyl)phenyl)boronic acid | 250mg | 716188588 | A486367 | 874460-03-4 | MFCD08235077 | 241.480 | C10H13BClNO3
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Sigma Aldrich Fine Chemicals Biosciences Methyl isoeugenol >=98%, FG | 93-16-3 | MFCD00009282 | 250G
Methyl isoeugenol >=98%, FG | Purity: >=98% | Mol Wt: 178.23 | 93-16-3 | MFCD00009282 | 250G
Sigma Aldrich Fine Chemicals Biosciences Cinnamyl alcohol >=98%, FG | 104-54-1 | MFCD00002921 | 10KG
Cinnamyl alcohol >=98%, FG | Purity: >=98% | Mol Wt: 134.18 | 104-54-1 | MFCD00002921 | 10KG
Indofine Chemical 4-Fluorostyrene, 98%, 5 Gm
4-FLUOROSTYRENE 5 GM, Fluoro Organics, 1-Fluoro-4-vinylbenzene, C8H7F, MW: 122.14, 95+%, 405-99-2, MFCD00000361
Indofine Chemical 3-Fluorostyrene, 98%, 5 Gm
3-FLUOROSTYRENE 5 GM, Fluoro Organics, 1-Fluoro-3-vinylbenzene, C8H7F, MW: 122.14, 0.98, 350-51-6, MFCD00000341