Sulfanilides
Medchemexpress LLC HY-11042 5mg Medchemexpress, GNE-477 CAS:1032754-81-6 Purity:>98%
Medchemexpress, HY-11042 5mg GNE-477 CAS:1032754-81-6 GNE-477 is a potent and efficacious dual PI3K (IC50=4 nM)/mTOR(Ki=21 nM) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0588 10mg Medchemexpress, Brinzolamide CAS:138890-62-7 Purity:>98%
Medchemexpress, HY-B0588 10mg Brinzolamide CAS:138890-62-7 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Methazolamide Fine Chemical | 554-57-4 | MFCD00083416 | 1 G
Methazolamide fine chemical | Purity: N/A | M.W.: 236.27 | 554-57-4 | MFCD00083416 | 1g
Medchemexpress LLC HY-103007 5mg Medchemexpress, TC-G-1008 CAS:1621175-65-2 Purity:>98%
Medchemexpress, HY-103007 5mg TC-G-1008 CAS:1621175-65-2 TC-G-1008 (GPR39-C3) is a potent and orally available GPR39 agonist with EC50 values of 0.4 and 0.8 nM for rat and human receptors respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Brinzolamide 138890-62-7 10mg
Brinzolamide (CAS 138890-62-7) is a potent and selective inhibitor of carbonic anhydrase II (CA II) with an IC50 of 3 19 nM and a Ki of 0 13 nM in vitro By inhibiting CA II brinzolamide disrupts the reversible hydration of carbon dioxide thereby reducing aqueous humor production and lowering intraocular pressure Demonstrated to have higher affinity and inhibitory efficacy for CA II compared to CA I and CA IV brinzolamide has been shown to significantly decrease intraocular pressure in animal models Additionally it is utilized in research settings to assess cerebral blood flow reserve as CA inhibition modulates tissue CO2 levels and consequent vasodilation
Medchemexpress LLC HY-12340 5mg Medchemexpress, ETP-46321 CAS:1252594-99-2 Purity:>98%
Medchemexpress, HY-12340 5mg ETP-46321 CAS:1252594-99-2 ETP-46321 is a potent and orally bioavailable PI3Kα and PI3Kδ inhibitor with Kiapps of 2.3 and 14.2 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Defactinib
Defactinib (VS-6063 PF-04554878) is a selective and orally active FAK inhibitor Phase 2
Medchemexpress LLC (R)-Bay-899 | 2988191-40-6 | 99.9% | 459.45 | C25H19F2N5O2 | 5 MG
(R)-BAY-899 is the R-enantiomer of BAY-899, an orally active, selective luteinizing hormone receptor (LH-R) antagonist used as a research tool for in vitro and in vivo studies. Supplied as an off-white to light yellow solid, the compound is characterized by high purity and includes documented solubility and storage conditions for laboratory applications.
- Selective LH-R antagonist for receptor signaling studies.
- High purity suitable for analytical and biological assays.
- Documented solubility in DMSO and multiple in vivo formulations.
- Stable powder storage at -20°C or 4°C with defined solvent stability.
- Available in small solid and solution pack sizes for research use.
Medchemexpress LLC BAY-899 | 2471967-92-5 | 99.9% | 50 MG
BAY-899 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist, functioning as a chemical probe. It demonstrates IC50s of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH), and is capable of reducing sex hormone levels. In vivo studies have shown that BAY-899 can reduce serum estradiol levels in intact female rats and exhibits a half-life of approximately 11-12 hours in Wistar rats.
- Orally active and selective luteinizing hormone receptor (LH-R) antagonist
- IC50s of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH)
- Capable of reducing sex hormone levels
- Inhibits human ERG expressed in HEK293 cells with an IC50 of 10.6 μM
- Reduced serum estradiol levels in intact female rats
Medchemexpress LLC Dpm-1001 | 1471172-27-6 | 99.8% | 5 MG
DPM-1001 is a small-molecule, orally bioavailable, non-competitive inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with a reported IC50 of approximately 100 nM. It is used in preclinical research to investigate insulin and leptin signaling and metabolic regulation.
- Non-competitive inhibitor of PTP1B (IC50 ≈ 100 nM).
- Orally bioavailable in preclinical models.
- Supports research into insulin and leptin signaling pathways.
- High reported purity suitable for biochemical assays.
- Stored cold to maintain stability and activity.
Medchemexpress LLC (R)-BAY-899 | 2988191-40-6 | 99.9% | 50 MG
(R)-BAY-899 is the R-enantiomer of BAY-899, an orally active and selective luteinizing hormone receptor (LH-R) antagonist. It exhibits IC50s of 185 nM for human LH and 46 nM for rat LH.
- Selective luteinizing hormone receptor antagonist
- Orally active
- IC50s: 185 nM for hLH, 46 nM for rLH
- Molecular weight: 459.45
- Chemical formula: C25H19F2N5O2
- Appearance: Off-white to light yellow solid
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- Solubility in DMSO: 125 mg/mL (272.06 mM)
- Solubility (in vivo): ≥ 5 mg/mL in various protocols
Medchemexpress LLC BAY-899 | 2471967-92-5 | 99.9% | 100 MG
BAY-899 is a chemical probe and an orally active, selective luteinizing hormone receptor (LH-R) antagonist. It is characterized by IC50s of 185 nM for human LH and 46 nM for rat LH, and has shown efficacy in reducing sex hormone levels in vivo. This product is intended for research use only.
- High purity of 99.93%
- Selective luteinizing hormone receptor (LH-R) antagonist
- Reduces sex hormone levels
- Potent inhibition with IC50s of 185 nM for human LH and 46 nM for rat LH
- Available as a white to off-white solid
- Stable as powder for up to 3 years at -20°C or 2 years at 4°C
Medchemexpress LLC Selexipag | 475086-01-2 | 496.62 | 100 MG
Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor). It is also described as an orally available and long-acting IP receptor agonist prodrug, with its active form being MRE-269.
- Orally available and potent agonist for the prostacyclin (PGI2) receptor (IP receptor)
- Long-acting IP receptor agonist prodrug; active form is MRE-269
- Inhibits binding of [3H]Iloprost to human and rat IP receptors
- Increases intracellular cAMP levels in hIP-CHO cells
- Inhibits platelet aggregation in humans and monkeys
Medchemexpress LLC Litronesib Racemate | 546111-97-1 | 99.2% | 511.70 | 100 MG
Litronesib Racemate is the racemate of litronesib, a selective, allosteric inhibitor of kinesin Eg5. It is designed for various research applications.
- Selective, allosteric inhibitor of kinesin Eg5
- Targets kinesin
- Involved in cell cycle/DNA damage pathway
- Involved in cytoskeleton pathway