Sulfanilides
Medchemexpress LLC HY-107429 10mg Medchemexpress, Abrocitinib CAS:1622902-68-4 Purity:>98%
Medchemexpress, HY-107429 10mg Abrocitinib CAS:1622902-68-4 Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 (IC50, 1.253 μM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 2471967-92-5 | Medchem Express | BAY-899 | 5mg | 582658993 | HY-130248 | 459.457 | C25H19F2N5O2
Pharmablock | 4-chloro-2-methyl-6-(trifluoromethyl)pyrimidine | 25mg | 746320005 | PBTKB0123 | 5993-98-6 | MFCD03265399 | 196.560 | C6H4ClF3N2
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eMolecules 313526-24-8 | Medchem Express | IBR2 | 5mg | 446258373 | HY-103710 | 400.5 | C24H20N2O2S
Ambeed | 4-Aminocyclohexanol hydrochloride | 1g | 525185534 | A321832 | 76445-65-3 | MFCD06410647 | 151.630 | C6H14ClNO
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Medchemexpress LLC (R)-BAY-899 | 2988191-40-6 | 99.9% | 100 MG
(R)-BAY-899 is the R-enantiomer of BAY-899, functioning as an orally active and selective luteinizing hormone receptor (LH-R) antagonist. It exhibits IC50 values of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH).
- Orally active
- Selective LH-R antagonist
- IC50 of 185 nM for human LH
- IC50 of 46 nM for rat LH
- Solid appearance
- Off-white to light yellow color
- High purity (99.9%)
- Soluble in DMSO (125 mg/mL)
Medchemexpress LLC BAY-899 | 2471967-92-5 | 99.9% | 50 MG
BAY-899 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist, functioning as a chemical probe. It demonstrates IC50s of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH), and is capable of reducing sex hormone levels. In vivo studies have shown that BAY-899 can reduce serum estradiol levels in intact female rats and exhibits a half-life of approximately 11-12 hours in Wistar rats.
- Orally active and selective luteinizing hormone receptor (LH-R) antagonist
- IC50s of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH)
- Capable of reducing sex hormone levels
- Inhibits human ERG expressed in HEK293 cells with an IC50 of 10.6 μM
- Reduced serum estradiol levels in intact female rats
eMolecules 1073160-26-5 | Medchem Express | Defactinib (hydrochloride) | 5mg | 446260957 | HY-12289A | MFCD28144730 | 546.95 | C20H22ClF3N8O3S
Medchem Express | Imatinib-d4 | 1mg | 533803321 | HY-15463S1 | 1134803-16-9 | 497.639 | C29H31N7O
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Medchemexpress LLC HY-12340 5mg Medchemexpress, ETP-46321 CAS:1252594-99-2 Purity:>98%
Medchemexpress, HY-12340 5mg ETP-46321 CAS:1252594-99-2 ETP-46321 is a potent and orally bioavailable PI3Kα and PI3Kδ inhibitor with Kiapps of 2.3 and 14.2 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC N-(cis-3-(methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)cyclobutyl)-1-propanesulfonamide | 1622902-68-4 | MFCD30187577 | >98.0% | 323.41 | C14H21N5O2S | 100 MG
Abrocitinib is a potent, orally active, and selective JAK1 inhibitor supplied as a research-grade analytical standard. It is provided as a purified solid suitable for in vitro pharmacology, assay development, and analytical reference. Chemical identity: N-(cis-3-(methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)cyclobutyl)-1-propanesulfonamide; CAS 1622902-68-4; formula C14H21N5O2S; molecular weight 323.41 g/mol.
- Potent, selective JAK1 inhibitor for mechanistic and screening studies.
- High purity (>98.0%) suitable for analytical and assay use.
- Solid powder form for accurate weighing and formulation.
- Well-characterized chemical identity with CAS 1622902-68-4.
- Appropriate for in vitro pharmacology and compound profiling.
Medchemexpress LLC BAY-899 | 2471967-92-5 | 99.9% | 100 MG
BAY-899 is a chemical probe and an orally active, selective luteinizing hormone receptor (LH-R) antagonist. It is characterized by IC50s of 185 nM for human LH and 46 nM for rat LH, and has shown efficacy in reducing sex hormone levels in vivo. This product is intended for research use only.
- High purity of 99.93%
- Selective luteinizing hormone receptor (LH-R) antagonist
- Reduces sex hormone levels
- Potent inhibition with IC50s of 185 nM for human LH and 46 nM for rat LH
- Available as a white to off-white solid
- Stable as powder for up to 3 years at -20°C or 2 years at 4°C
![Medchemexpress LLC 3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide | 781628-99-7 | 98.0% | 483.54 g/mol | C24H25N3O6S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237142.png-250.jpg)
Medchemexpress LLC 3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide | 781628-99-7 | 98.0% | 483.54 g/mol | C24H25N3O6S | 10MG
SBI-477 is a small-molecule chemical probe that stimulates insulin signaling by deactivating the transcription factor MondoA, resulting in reduced expression of insulin-pathway suppressors and coordinated inhibition of triacylglyceride synthesis while enhancing basal glucose uptake in human skeletal myocytes.
- Deactivates MondoA to stimulate insulin signaling.
- Reduces TXNIP and ARRDC4 expression.
- Inhibits triacylglyceride synthesis and increases basal glucose uptake.
- Provided as a solid powder, supplied in a 10 mg package.
- High purity: 98.0%.
- Recommended storage: powder at -20°C (long-term) or 4°C (shorter term).
eMolecules 1159824-67-5 | Medchem Express | CZC24832 | 5mg | 446265371 | HY-15294 | MFCD22417090 | 364.4 | C15H17FN6O2S
Ambeed | (S)-3-((tert-Butoxycarbonyl)amino)-5-(methylthio)pentanoic acid | 1g | 525150500 | A245403 | 1217811-51-2 | MFCD06202399 | 263.350 | C11H21NO4S
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Medchemexpress LLC HY-B0109A 10mg Medchemexpress, Dorzolamide (hydrochloride) CAS:130693-82-2 Purity:>98%
Medchemexpress, HY-B0109A 10mg Dorzolamide (hydrochloride) CAS:130693-82-2 Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor, with IC50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity.
Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-103007 5mg Medchemexpress, TC-G-1008 CAS:1621175-65-2 Purity:>98%
Medchemexpress, HY-103007 5mg TC-G-1008 CAS:1621175-65-2 TC-G-1008 (GPR39-C3) is a potent and orally available GPR39 agonist with EC50 values of 0.4 and 0.8 nM for rat and human receptors respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC (R)-BAY-899 | 2988191-40-6 | 99.9% | 50 MG
(R)-BAY-899 is the R-enantiomer of BAY-899, an orally active and selective luteinizing hormone receptor (LH-R) antagonist. It exhibits IC50s of 185 nM for human LH and 46 nM for rat LH.
- Selective luteinizing hormone receptor antagonist
- Orally active
- IC50s: 185 nM for hLH, 46 nM for rLH
- Molecular weight: 459.45
- Chemical formula: C25H19F2N5O2
- Appearance: Off-white to light yellow solid
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- Solubility in DMSO: 125 mg/mL (272.06 mM)
- Solubility (in vivo): ≥ 5 mg/mL in various protocols
Medchemexpress LLC HY-B0124 200mg Medchemexpress, Zonisamide CAS:68291-97-4 Purity:>98%
Medchemexpress, HY-B0124 200mg Zonisamide CAS:68291-97-4 Zonisamide (AD 810; CI 912) is an inhibitor of zinc enzyme carbonic anhydrase (CA), with Kis of 35.2 nM and 20.6 nM for human mitochondrial isozyme hCA II and hCA V, respectively. Zonisamide has antiepileptic activity. Zonisamide can be used for the rsearch for epilepsy, seizures and Parkinson's disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.