Tosyl compounds
Sigma Aldrich 1H-Indole-6-methanamine
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Sigma Aldrich 6-Amino-4H-chromen-4-one
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Sigma Aldrich 6-(4-Chlorophenyl)-4,5-dihydropyridazin-3(2H)-one
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Methylthiomethyl p-Tolyl Sulfone 98.0+%, TCI America™
CAS: 59662-65-6 Molecular Formula: C9H12O2S2 Molecular Weight (g/mol): 216.313 MDL Number: MFCD00010750 InChI Key: XAARLLNXZJTFPQ-UHFFFAOYSA-N Synonym: methylthiomethyl p-tolyl sulfone,methyl tosylmethyl sulfane,mt-sulfone,methylmercaptomethyl p-tolyl sulfone,1-methyl-4-methylsulfanylmethylsulfonyl benzene,1-methyl-4-methylsulfanyl methanesulfonylbenzene,methylthiomethylp-tolylsulfone,acmc-209mf0,methyl thiomethyl p-tolylsulfone,xaarllnxzjtfpq-uhfffaoysa PubChem CID: 548421 IUPAC Name: 1-methyl-4-(methylsulfanylmethylsulfonyl)benzene SMILES: CC1=CC=C(C=C1)S(=O)(=O)CSC
Potassium p-Toluenethiosulfonate 98.0+%, TCI America™
CAS: 28519-50-8 Molecular Formula: C7H7KO2S2 Molecular Weight (g/mol): 226.349 MDL Number: MFCD00003547 InChI Key: RUDNWZFWWJFUSF-UHFFFAOYSA-M Synonym: p-Toluenethiosulfonic Acid Potassium Salt PubChem CID: 23662126 IUPAC Name: potassium;(4-methylphenyl)-oxido-oxo-sulfanylidene-$l^{6}-sulfane SMILES: CC1=CC=C(C=C1)S(=O)(=S)[O-].[K+]
p-Toluenesulfonyl chloride, 99+%
CAS: 98-59-9 Molecular Formula: C7H7ClO2S Molecular Weight (g/mol): 190.64 MDL Number: MFCD00007450 InChI Key: YYROPELSRYBVMQ-UHFFFAOYSA-N Synonym: tosyl chloride,p-toluenesulfonyl chloride,p-tosyl chloride,4-toluenesulfonyl chloride,p-toluenesulfochloride,4-methylbenzene-1-sulfonyl chloride,p-tolylsulfonyl chloride,p-toluenesulphonyl chloride,tosylchloride,p-toluenesulfonic acid chloride PubChem CID: 7397 IUPAC Name: 4-methylbenzenesulfonyl chloride SMILES: CC1=CC=C(C=C1)S(Cl)(=O)=O
p-Toluenesulfonyl fluoride, 98%
CAS: 455-16-3 Molecular Formula: C7H7FO2S Molecular Weight (g/mol): 174.189 MDL Number: MFCD00007421 InChI Key: IZZYABADQVQHLC-UHFFFAOYSA-N Synonym: p-toluenesulfonyl fluoride,tosyl fluoride,4-toluenesulfonyl fluoride,benzenesulfonyl fluoride, 4-methyl,4-tolylsulfonyl fluoride,toluene-4-sulfonyl fluoride,p-methylbenzenesulfonyl fluoride,p-toluenesulphonyl fluoride,toluene-p-sulphonyl fluoride,p-methylphenylsulfonyl fluoride PubChem CID: 9965 IUPAC Name: 4-methylbenzenesulfonyl fluoride SMILES: CC1=CC=C(C=C1)S(=O)(=O)F
Tosylmethyl isocyanide, 98%
CAS: 36635-61-7 Molecular Formula: C9H9NO2S Molecular Weight (g/mol): 195.24 MDL Number: MFCD00000005 InChI Key: CFOAUYCPAUGDFF-UHFFFAOYSA-N Synonym: tosylmethyl isocyanide,tosmic,p-toluenesulfonylmethyl isocyanide,4-toluenesulphonylmethyl isocyanide,4-toluenesulfonylmethyl isocyanide,tosylmethylisocyanide,1-isocyanomethylsulfonyl-4-methylbenzene,p-tolylsulfonyl methyl isocyanide,unii-c35fd6olh8,1-isocyanomethyl sulfonyl-4-methylbenzene PubChem CID: 161915 IUPAC Name: 1-(isocyanomethylsulfonyl)-4-methylbenzene SMILES: CC1=CC=C(C=C1)S(=O)(=O)C[N+]#[C-]
Medchemexpress LLC Biotin sulfone | 40720-05-6 | 99.8% | 276.31 | 1 ML
Biotin sulfone, a structural analog and metabolite of Biotin, exerts competitive inhibition against Biotin in Lactobacillus arabinosus 17-5.
- Structural analog and metabolite of Biotin
- Exerts competitive inhibition against Biotin in Lactobacillus arabinosus 17-5
- Binds tightly to streptavidin with performance comparable to that of Biotin
- For research use only.
Medchemexpress LLC Biotin sulfone | 40720-05-6 | 99.8% | 276.31 | 10 MG
Biotin sulfone is a structural analog and metabolite of Biotin. It competitively inhibits Biotin in *Lactobacillus arabinosus* 17-5 and binds tightly to streptavidin.
- Competitively inhibits biotin utilization by *Lactobacillus arabinosus*
- Binds tightly to streptavidin
- Soluble in DMSO at 250 mg/mL
- Available as a solid
Medchemexpress LLC Biotin sulfone | 40720-05-6 | 99.8% | 276.31 | 25 MG
Biotin sulfone is a structural analog and metabolite of Biotin. It competitively inhibits Biotin in Lactobacillus arabinosus 17-5. The inhibitory potency is regulated by medium additives, with the inhibition index increasing with aspartic acid, Tween 80, and a combination of lysine, threonine, and uracil. Biotin sulfone binds tightly to streptavidin with performance comparable to that of Biotin.
- Structural analog and metabolite of Biotin
- Competitively inhibits Biotin in Lactobacillus arabinosus 17-5
- Binds tightly to streptavidin
- Appearance: Solid, white to off-white
- Can be stored for extended periods in powder form
- Detailed solubility and dissolution protocols provided for in vitro and in vivo experiments
Medchemexpress LLC N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride | 4272-74-6 | 99.0% | 369.31 | 25 MG
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK) is a trypsin-like protease inhibitor that sensitizes HeLa cells to Fas-mediated cell death. It also exhibits an inhibitory effect on IFN-γ activities. This product is for research use only.
- Trypsin-like protease inhibitor
- Sensitizes HeLa cells to Fas-mediated cell death
- Exhibits an inhibitory effect on IFN-γ activities
- Soluble in H2O and DMSO at concentrations ≥ 100 mg/mL (270.78 mM)
Medchemexpress LLC N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride | 4272-74-6 | 99.0% | 369.31 | 1 ML
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK) is a trypsin-like protease inhibitor that sensitizes HeLa cells to Fas-mediated cell death. It exhibits an inhibitory effect on IFN-γ activities and enhances the decrease in cell survival when combined with anti-Fas. This product is for research use only.
- Acts as a trypsin-like protease inhibitor
- Sensitizes HeLa cells to Fas-mediated cell death
- Inhibits IFN-γ activities
- Enhances cell death in combination with anti-Fas
- Suitable for research applications
Medchemexpress LLC N-alpha-tosyl-L-lysine chloromethyl ketone hydrochloride | 4272-74-6 | MFCD00065395 | 99.0% | 369.31 g/mol | C14H21ClN2O3S·HCl | 5 MG
N-alpha-tosyl-L-lysine chloromethyl ketone hydrochloride (TLCK) is an irreversible inhibitor of trypsin and trypsin-like serine proteases. It is used in biochemical and cell biology research to suppress trypsin-like proteolytic activity, probe protease-dependent signaling, and support studies of apoptosis and related pathways.
- Irreversible inhibitor of trypsin-like serine proteases.
- High purity suitable for biochemical assays and analytical work.
- Solid, white to off-white form for convenient storage and handling.
- Commonly used in protease inhibition assays and signal-transduction studies.
- Reported to sensitize HeLa cells to Fas-mediated cell death, useful in apoptosis research.
Sigma Aldrich 2,4,6-Tri(P-Tolyl)Pyrylium Tetrafluoroborate Salt
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.