Aminophenols
Medchemexpress LLC PKI-179 hydrochloride | 1463510-35-1 | 99.66% | 525.00 | 10 MG
PKI-179 hydrochloride is a potent and orally active dual PI3K/mTOR inhibitor. It exhibits activity over various PI3K isoforms and mTOR, along with E545K and H1047R. This compound demonstrates anti-tumor activity in vivo.
- Potent and orally active dual PI3K/mTOR inhibitor
- Inhibits PI3K-α, PI3K-β, PI3K-γ, PI3K-δ and mTOR
- Shows activity over E545K and H1047R
- Exhibits anti-tumor activity in vivo
Medchemexpress LLC UNC9994 hydrochloride | 2108826-33-9 | 99.5% | 457.84 | 50 MG
UNC9994 hydrochloride | 2108826-33-9 | 99.5% | 457.84 | 50 MG
Cayman Chemical N-acetyl-2-AmInophenol 250g
A derivative of acetaminophen; inhibits ADP- or arachidonic acid-induced platelet aggregation in isolated human platelet-rich plasma at 50 µM; decreases disease severity and prevents increases in paw volume in a rat model of collagen-induced arthritis at 1 mg/kg; has been used as a synthetic intermediate in the synthesis of compounds with antimalarial activity; a potential impurity in commercial preparations of acetaminophen
Medchemexpress LLC S-14506 hydrochloride | 286369-38-8 | 99.92% | 443.94 | 100 MG
S-14506 hydrochloride is a potent 5-HT1A agonist and a 5-HT2A/2C antagonist. It also exhibits dopamine antagonist properties by blocking dopamine D2 receptors, inhibiting the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. This compound has potential for research as an anxiolytic agent.
- Potent 5-HT1A agonist
- 5-HT2A/2C antagonist
- Exhibits dopamine D2 receptor blocking properties
- Potential for research as an anxiolytic agent
Medchemexpress LLC A 85380 hydrochloride | 174740-86-4 | ≥97.0% | 237.13 | 50 MG
A 85380 hydrochloride is a novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist. It exhibits selectivity for the α4β2 nAChR subtypes and has a broad-spectrum analgesic profile.
- Novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist.
- Selectivity for the α4β2 nAChR subtypes.
- Broad-spectrum analgesic profile.
- For research use only.
Medchemexpress LLC Tacrine hydrochloride | 1684-40-8 | 99.9% | 1 ML
Tacrine hydrochloride is a potent brain-penetrant inhibitor of both AChE and BChE. It also acts as an NMDAR inhibitor. This compound can be utilized in research related to Alzheimer's disease.
- Potent brain-penetrant inhibitor of AChE and BChE.
- NMDAR inhibitor.
- Used for Alzheimer's disease research.
- Appearance: Solid, white to light yellow.
- Shipping: Room temperature in continental US.
- Storage: 4°C, stored under nitrogen, away from moisture.
- In solvent storage: -80°C for 6 months; -20°C for 1 month (stored under nitrogen, away from moisture).
- Solubility in H2O: 33.33 mg/mL (141.99 mM; needs ultrasonic).
Matrix Scientific 1-(4-HYDROXYPHENYL)PIPERAZI-10
1-(4-hydroxyphenyl)piperazine Mf C10h14n2o Mw 178.24 Cas 56621-48-8 Mdl MFCD00066156
STA PHARMACEUTICAL US LLC Fmoc-(S)-3-Amino-3-(4-hydroxyphenyl)-propionic acid | 25 g | CAS 501015-33-4 | MDL MFCD03427979
Fmoc-(S)-3-Amino-3-(4-hydroxyphenyl)-propionic acid is a Amino Acid reagent (Subcategory: Beta AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 501015-33-4
- MDL: MFCD03427979
- InChIKey: VJELJMCALKYCRN-QFIPXVFZSA-N
- Molecular Weight: 403.434
- Molecular Formula: C24H21NO5
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid
- SMILES: O=C(C[C@H](NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)C4=CC=C(C=C4)O)O
eMolecules 50297-40-0 | 3-Chloro-N-(3-hydroxyphenyl)propanamide | Oakwood Chemical | MFCD02812236 | 199.630 | C9H10ClNO2 | 95.000 | Oc1cccc(NC(=O)CCCl)c1 | 250mg | 537720169
3-Chloro-N-(3-hydroxyphenyl)propanamide | Oakwood Chemical | 50297-40-0 | MFCD02812236 | 199.630 | C9H10ClNO2 | 95.000 | Oc1cccc(NC(=O)CCCl)c1 | 250mg | 537720169
Medchemexpress LLC AT7519 Hydrochloride | 902135-91-5 | 99.2% | C16H18Cl3N5O2 | 100 MG
AT7519 Hydrochloride is a potent inhibitor of Cyclin-Dependent Kinases (CDKs), exhibiting strong inhibitory activity against CDK1, CDK2, CDK4 to CDK6, and CDK9. It induces dose-dependent cytotoxicity and apoptosis in MM cells and inhibits cell cycle progression in various human tumor cell lines. In preclinical studies, AT7519 Hydrochloride effectively inhibits tumor growth in both human MM and HCT116 xenograft mouse models.
- Potent inhibitor of CDKs (IC50 values range from <10 nM to 210 nM)
- Induces cytotoxicity and apoptosis in MM cells
- Overcomes cytokine and BMSC protective effects
- Inhibits RNA polymerase II CTD phosphorylation and RNA synthesis
- Inhibits cell cycle progression and induces apoptosis in tumor cell lines
- Reduces antiapoptotic protein levels
- Inhibits tumor growth in MM and HCT116 xenograft models
Medchemexpress LLC UNC9994 hydrochloride | 2108826-33-9 | 99.5% | 457.84 | 25 MG
UNC9994 hydrochloride is a functionally selective, β-arrestin-biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. It exhibits a binding affinity with a Ki of 79 nM for D2R. This compound also acts as an antagonist of Gi-regulated cAMP production and a partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride demonstrates antipsychotic-like activity. For research use only.
- Selectively activates β-arrestin recruitment and signaling
- Exhibits binding affinity with a Ki of 79 nM for D2R
- Acts as an antagonist of Gi-regulated cAMP production
- Functions as a partial agonist for D2R/β-arrestin-2 interactions
- Demonstrates antipsychotic-like activity
Medchemexpress LLC Triacetonamine (2,2,6,6-tetramethyl-4-piperidone) | 826-36-8 | MFCD00005975 | 155.24 | 1000 G
Triacetonamine is utilized as an intermediate in the synthesis of pharmaceutical products, pesticides, and photostabilizers for polymers. It exhibits oral activity and can induce acute liver failure (ALF) in rats.
- Used as an intermediate for the synthesis of pharmaceutical products, pesticides, and photostabilizers for polymers
- Has oral activity
- Can induce acute liver failure (ALF) in rats