Aminophenols
Medchemexpress LLC Guvacine hydrochloride | 6027-91-4 | MFCD00055191 | 99.9% | 163.60 g/mol | C6H10ClNO2 | 25 MG
Guvacine hydrochloride is the hydrochloride salt of guvacine, a pyridine alkaloid that acts as a GABA uptake inhibitor. Supplied as a high-purity research reagent, it is used in biochemical and neuropharmacological studies to probe GABA transporter activity. The substance is intended for laboratory research use only and is not for human or veterinary use.
- High purity (99.93%) for reliable experimental results.
- Molecular weight 163.60 g/mol.
- Molecular formula C6H10ClNO2.
- CAS number 6027-91-4 for unambiguous identification.
- Available in multiple pack sizes and solution formats for flexible use.
- Suitable for in vitro biochemical and pharmacology research.
Medchemexpress LLC G-5555 hydrochloride | 2319590-15-1 | 98.3% | 529.42 | 1 ML
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.
- Excellent kinase selectivity, inhibiting only eight out of 235 kinases tested (>70% inhibition).
- High selectivity for group I PAKs.
- Negligible activity against the hERG channel (IC50 > 10 μM).
- Exhibits significantly greater growth inhibitory activity in PAK-amplified breast cancer cell lines.
- Low blood clearance and acceptable half-life in vivo.
- Good oral exposure (AUC=30 μM•h) and high oral bioavailability (F=80%) in vivo.
- Inhibits phosphorylation of MEK1 S298 and shows 60% tumor growth inhibition in xenograft models.
Cambridge Isotope Laboratories 4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
eMolecules 3,4-Diaminophenol | 615-72-5 | MFCD06799539 | 1g
Combi-Blocks | 3,4-Diaminophenol | 1g | 205381631 | AN-3892 | 96.000 | 615-72-5 | MFCD06799539 | 124.143 | C6H8N2O
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Medchemexpress LLC MRE-269-d7 | 1265295-20-2 | 99.6% | C25H22D7N3O3 | 5 MG
MRE-269-d7 is a deuterium-labeled version of MRE-269, an active metabolite of selexipag that acts as a selective IP receptor agonist. It is intended for research use and can serve as a tracer and an internal standard for quantitative analysis. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled version of MRE-269
- Active metabolite of selexipag
- Selective IP receptor agonist
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC CC-401 hydrochloride | 1438391-30-0 | 99.35% | 25 MG
CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM. It exhibits at least 40-fold selectivity for JNK compared with other related kinases, including p38, extracellular signal-regulated kinase (ERK), inhibitor of κB kinase (IKK2), protein kinase C, Lck, and zeta-associated protein of 70 kDa (ZAP70).
- Competitively binds the ATP binding site in JNK.
- Inhibits phosphorylation of the N-terminal activation domain of the transcription factor c-Jun.
- Demonstrates specificity in vitro using osmotic stress of the HK-2 human tubular epithelial cell line.
- Inhibits sorbitol-induced phosphorylation of c-Jun in a dosage-dependent manner.
- Does not prevent sorbitol-induced phosphorylation of JNK, p38, or ERK induced by sorbitol.
- Provides specific JNK inhibition in cell-based assays at 1 to 5 μM.
Medchemexpress LLC L-NAME (hydrochloride) | 51298-62-5 | 99.9% | 269.69 | 5 G
L-NAME hydrochloride is an inhibitor of nitric oxide synthase (NOS) with an IC50 of 70 μM. It acts as a precursor to the NOS inhibitor L-NOARG, which has an IC50 value of 1.4 μM. It is used for research purposes only and is not sold to patients.
- Inhibits NOS with an IC50 of 70 μM.
- Precursor to the more potent NOS inhibitor L-NOARG (IC50 = 1.4 μM).
- Can be used to induce hypertension models in animals.
- Can be used to induce preeclampsia models in animals.
Medchemexpress LLC Zilpaterol-d7 | 1217818-36-4 | C14H12D7N3O2 | 1 MG
Zilpaterol-d7 is a deuterium Zilpaterol. Zilpaterol is a β-adrenergic agonist that has been widely used to feed cattle.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC HAIYPRH hydrochloride | 100.0% | 929.46 | 5 MG
HAIYPRH hydrochloride is a targeting ligand that specifically binds to the transferrin receptor (TfR). It can mediate the transport of nanocarriers across the blood-brain barrier.
- Can be conjugated to liposomes for ischemic stroke targeting treatment.
- Heptapeptide that can be used to target gliomas.
- Used as a ligand to target co-delivery systems to tumor cells expressing transferrin receptors.
- Modified co-delivery systems show higher efficiency in cellular uptake and gene expression in U87 MG cells.
- Modified co-delivery systems accumulate in tumors more efficiently in vivo.
Medchemexpress LLC BIIL-260 hydrochlori | 100MG
BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist with anti-inflammatory activity BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable reversible and competitive manner has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1 7 nM[1]
eMolecules AstaTech / 4-AMINO-2-NITROPHENOL / 1g / 482599101 / F20388 / 95.000 / 119-34-6 / MFCD00007876 / 154.125 / C6H6N2O3
AstaTech / 4-AMINO-2-NITROPHENOL / 1g / 482599101 / F20388 / 95.000 / 119-34-6 / MFCD00007876 / 154.125 / C6H6N2O3
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 5 MG
Hypidone hydrochloride is a research-grade, orally active antidepressant used in preclinical pharmacology to study serotonergic mechanisms. It functions as a selective serotonin uptake inhibitor and a potent 5-HT1A receptor agonist, showing low-nanomolar activity in uptake and receptor assays. Supplied as a white to off-white solid with high purity for laboratory use.
- Orally active antidepressant with dual mechanism of action.
- Highly potent 5-HT uptake inhibitor and 5-HT1A receptor agonist.
- High purity suitable for preclinical research.
- Available in small milligram package sizes and DMSO solution format.
- Soluble in DMSO and supplied with recommended storage conditions.
![Medchemexpress LLC 2-pyridinemethanol, α-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-α-phenyl-, hydrochloride | 61477-94-9 | MFCD01691662 | 99.3% | 374.95 g/mol | C22H31ClN2O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213420.png-250.jpg)
Medchemexpress LLC 2-pyridinemethanol, α-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-α-phenyl-, hydrochloride | 61477-94-9 | MFCD01691662 | 99.3% | 374.95 g/mol | C22H31ClN2O | 1 ML
Pirmenol hydrochloride is an antiarrhythmic research compound supplied for laboratory use as a 10 mM solution in DMSO (1 mL) or as a solid with solvent. It inhibits IK.ACh and is intended for preclinical cardiovascular and ion-channel research. The material is characterized by high purity and is accompanied by a certificate of analysis.
- Provided as 10 mM in DMSO, 1 mL stock solution or solid plus solvent
- High purity, 99.3%
- Molecular formula C22H31ClN2O; molecular weight 374.95 g/mol
- CAS number 61477-94-9
- Storage: solid at 4°C under nitrogen; in solvent -80°C for 6 months, -20°C for 1 month
- Suitable for cardiovascular and ion-channel research applications
Medchemexpress LLC Metixene hydrochloride monohydrate | 7081-40-5 | >95.0% | 100MG
Metixene hydrochloride monohydrate | 7081-40-5 | >95.0% | 100MG
Medchemexpress LLC R 59-022 (hydrochloride) | 93076-98-3 | MFCD34676749 | 98.9% | 496.04 g·mol⁻¹ | C27H27ClFN3OS | 50 MG
R 59-022 hydrochloride is the hydrochloride salt of R 59-022, a research compound that acts as a diacylglycerol kinase (DGK) inhibitor (reported IC50 ≈ 2.8 μM). It is used in cellular and biochemical assays to modulate diacylglycerol/protein kinase C signaling and to probe 5-HT receptor-related pathways. The material is supplied as an off-white solid (CAS 93076-98-3) with formula C27H27ClFN3OS and molecular weight 496.04 g·mol⁻¹.
- DGK inhibitor with reported IC50 ≈ 2.8 μM.
- Modulates protein kinase C and diacylglycerol signaling in cells.
- Hydrochloride salt form for improved handling and solubility in polar solvents.
- High purity suitable for research applications.
- Soluble in DMSO for preparation of stock solutions.