Aminophenols
eMolecules 127818-58-0 | 3-METHYL-5-NITROPHENOL | MFCD09038591 | 1g
Ambeed | 13-Benzenedimethanamine | 25g | 600851593 | A566345 | 1477-55-0 | MFCD00008119 | 136.198 | C8H12N2
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Medchemexpress LLC GSK 690 Hydrochlorid 10mM 1mL | 2436760-79-9 | 405.92 | C24H24ClN3O | 1 ML
GSK 690 Hydrochloride is a reversible inhibitor of lysine-specific demethylase 1 (LSD1) with reported Kd 9 nM and biochemical IC50 37 nM. It is supplied for research use in solution and solid formats and is characterized by high purity suitable for biochemical assays.
- Reversible LSD1 inhibitor with Kd 9 nM and IC50 37 nM.
- Supplied as 10 mM solution in DMSO (1 mL) and as solid quantities.
- High purity (98.58%) suitable for biochemical and cell-based studies.
- Molecular weight 405.92 and formula C24H24ClN3O.
- Storage: sealed at 4°C; in solvent: -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC 3-(benzyl(isopropyl)amino)-1-(naphthalen-2-yl)propan-1-one hydrochloride | 1021868-92-7 | MFCD04974534 | >98.0% | 367.91 g/mol | C23H26ClNO | 10MM 1ML
ZM39923 hydrochloride is a small-molecule JAK3 inhibitor used in research. It displays JAK3 potency (pIC50 = 7.1) and also inhibits tissue transglutaminase (TGM2) with an IC50 of 10 nM; it is supplied as a 10 mM solution in DMSO and in solid quantities.
- Small-molecule JAK3 inhibitor (pIC50 = 7.1).
- Potent TGM2 inhibition (IC50 = 10 nM).
- Available as 10 mM solution in DMSO and in solid forms.
- Molecular formula C23H26ClNO.
- Molecular weight 367.91 g/mol.
- Purity >98.0% by HPLC.
- For research use only.
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | 98.2% | 50 MG
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. It inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. This compound demonstrates broad antiviral activities against Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae, with EC50 values ranging from 0.02-1.21 μM. It is suitable for research related to infection.
- Selective inhibitor of CDK7
- Inhibits human cytomegalovirus (HCMV) replication
- Broad antiviral activities against various viruses
- Suitable for infection research
- Exhibits anti-proliferative activity in human fibroblasts
- Demonstrates good oral bioavailability and half-life in vivo
Medchemexpress LLC Mepazine hydrochloride | 2975-36-2 | 99.3% | 5 MG
Mepazine hydrochloride is the hydrochloride salt of mepazine, supplied for research use as a solid or as a DMSO solution and intended for in vitro biochemical and cellular assays.
- High purity (99.25%).
- Molecular formula C19H23ClN2S.
- Molecular weight 346.92 g/mol.
- Available in small solid packs and a 10 mM DMSO solution format.
- Store sealed at 4°C; in solution, store at -80°C for long-term stability.
Medchemexpress LLC Abaucin hydrochloride | 1173022-16-6 | >98% | 426.86 | 1 ML
Abaucin hydrochloride is a potent CCR2 antagonist (IC50: 360 nM) with no effect on CCR1, primarily used in neurological disease and endocrinology research. It targets human α1a, α1d receptors, and rat brain cortex 5HT1a receptor, and suppresses wild type and D284N mutant MCP-1 receptor activity. In vivo studies show it decreases pain thresholds in rats with bone cancer pain.
- Potent CCR2 antagonist (IC50: 360 nM), no effect on CCR1
- Inhibits α1a, α1d, and 5HT1a receptors
- Suppresses wild type and D284N mutant MCP-1 receptor
- Reduces extracellular matrix protein expression
- Blocks fibronectin and type IV collagen expression in high glucose-stimulated mesangial cells
- Abrogates increased TGF-1 levels in mesangial cells
- Decreases pain threshold in rats with bone cancer pain
- Reverses NR2B, nNOS, and SIGIRR expression in spinal cord
- Used in neurological disease and endocrinology research
Medchemexpress LLC SR9011 hydrochloride | 2070014-94-5 | 99.0% | 515.50 | 2 MG
SR9011 hydrochloride is a potent REV-ERBα/β agonist (IC50s: 790 nM for REV-ERBα, 560 nM for REV-ERBβ). It significantly increases REV-ERB-dependent repressor activity and suppresses transcription via full-length REV-ERBα. The compound inhibits BMAL1 mRNA expression in HepG2 cells and suppresses breast cancer cell proliferation by halting the cell cycle before M phase. In mice, SR9011 suppresses REV-ERB responsive genes and temporarily reduces locomotor activity during the dark phase.
- Potent REV-ERBα/β agonist.
- Increases REV-ERB-dependent repressor activity.
- Suppresses transcription via full-length REV-ERBα.
- Inhibits BMAL1 mRNA expression in HepG2 cells.
- Suppresses breast cancer cell proliferation.
- Pauses cell cycle prior to M phase, increasing G0/G1 phase cells.
- Suppresses REV-ERB responsive genes in mice.
- Reduces locomotor activity in mice under dark conditions.
Medchemexpress LLC P-amidinophenylmethylsulfonylfluoride hydrochloride | 74938-88-8 | MFCD00078902 | 95.0% | 252.69 | C8H10ClFN2O2S | 1 MG
p-APMSF hydrochloride is the hydrochloride salt of p-amidinophenylmethylsulfonylfluoride, an irreversible serine protease inhibitor selective for substrates with positively charged side chains such as lysine and arginine. It is provided as a high-purity research reagent for enzymology and biochemical assays.
- Irreversible serine protease inhibitor selective for positively charged side chains.
- Provided as the hydrochloride salt to aid solubility in aqueous assays.
- High purity (95.0%) suitable for research and assay development.
- Molecular weight 252.69; formula C8H10ClFN2O2S.
- Offered in small-scale packaging (1 mg) for screening and mechanistic studies.
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 25MG
Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 25MG
Medchemexpress LLC UNC2025 hydrochloride | 2070015-17-5 | 100.0% | 513.12 | C28H41ClN6O | 10MM 1ML
UNC2025 hydrochloride is the hydrochloride salt of UNC2025, a potent, ATP-competitive, orally active dual MERTK/FLT3 inhibitor used in preclinical research on acute leukemia and receptor tyrosine kinase signaling. Supplied as a 10 mM solution in DMSO (1 mL), it exhibits sub-nanomolar inhibition of MERTK and FLT3 and demonstrates favorable pharmacokinetic properties for in vitro and in vivo studies.
- Potent MERTK and FLT3 inhibition at sub-nanomolar concentrations.
- Supplied as a ready-to-use 10 mM solution in DMSO for convenient dosing.
- High purity for reproducible experimental results.
- Light yellow to yellow solid appearance when provided as a dry compound.
- Store sealed and protect from moisture; in solution store at -80°C for long-term stability.
Medchemexpress LLC Tecalcet hydrochloride | 177172-49-5 | MFCD16038895 | 99.7% | 340.29 g/mol | C18H23Cl2NO | 1 ML
Tecalcet hydrochloride is an orally active calcimimetic that allosterically and positively modulates the calcium-sensing receptor (CaSR). It is provided for research use in solution and solid forms and is commonly used in in vitro pharmacology and calcium-signaling studies.
- Orally active calcimimetic that modulates the calcium-sensing receptor.
- Suitable for in vitro pharmacology and CaSR signaling studies.
- Available as a 10 mM solution in DMSO (1 mL) and as solid quantities for formulation flexibility.
- High chemical purity (≈99.7%) for reliable experimental results.
- Molecular weight 340.29 g/mol and molecular formula C18H23Cl2NO.
