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Filtered Search Results
eMolecules 2,4-Difluoro-5-iodophenol | 1935521-44-0 | MFCD28986198 | 1g
Apollo Scientific | 2,4-Difluoro-5-iodophenol | 1g | 562441763 | PC52128 | | 1935521-44-0 | MFCD28986198 | 255.990 | C6H3F2IO
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Medchemexpress LLC 3,3-Dimethylacrylic acid | 541-47-9 | 99.99% | 100.12 | 50 G
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3,3-Dimethylacrylic acid is an active small molecule that can be used as a drug intermediate. It exhibits antituberculosis activity with a MIC of 0.078 μg/mL and can be used for the synthesis of triorganotin(IV) complexes of cinnamic acid. It is for research use only and not sold to patients. It has an appearance of a solid, white to off-white color. It is classified under Ketones, Aldehydes, Acids and its initial source is an endogenous metabolite.
- Exhibits antituberculosis activity with a MIC of 0.078 μg/mL.
- Can be used for the synthesis of triorganotin(IV) complexes of cinnamic acid.
- For research use only.
- Appearance: solid, white to off-white color.
- Classified under ketones, aldehydes, acids.
- Initial source is an endogenous metabolite.
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Ambeed 3 3 5 5 Tetramethyl 1 1 biphe
3,3',5,5'-Tetramethyl-[1,1'-biphenyl]-4,4'-diamine, 54827-17-7, 98%
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Medchemexpress LLC Avotaciclib hydrochloride | 1983983-41-0 | 99.75% | 317.73 | 50 MG
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Avotaciclib hydrochloride is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. It inhibits the proliferation and induces apoptosis of tumor cells, and can be used in the research of cancers such as pancreatic cancer and lung cancer. This potent compound targets CDK1 activity, which may inhibit cancer stem cell division, lead to cell cycle arrest, and induce apoptosis, thereby inhibiting tumor cell proliferation.
- Orally active CDK1 inhibitor
- Inhibits proliferation and induces apoptosis of tumor cells
- Useful in research for cancers such as pancreatic cancer and lung cancer
- Targets and inhibits CDK1 activity
- May inhibit cancer stem cell division
- Leads to cell cycle arrest
- Induces apoptosis
- Potential antitumor activity
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Medchemexpress LLC Dronedarone Hydrochloride | 141625-93-6 | 99.99% | C31H45ClN2O5S | 100 MG
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Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+, and Ca2+ currents. It serves as a multichannel blocker for atrial fibrillation, making it suitable for various research applications.
- Inhibits Na+, K+, and Ca2+ currents.
- Potently blocks acetylcholine-activated K+ current.
- Blocks IKr and ICa-L with specific IC50 values.
- Exhibits state-dependent inhibition of fast Na+ channel current.
- Significantly reduces incidence of ventricular fibrillation in vivo.
- Inhibits carotid artery thrombus formation in vivo.
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Medchemexpress LLC Oxidopamine hydrochloride | 28094-15-7 | 99.9% | 50 MG
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Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. It is a widely used neurotoxin that selectively destroys dopaminergic neurons. It promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion and can be used for the research of Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
- Selectively destroys dopaminergic neurons.
- Promotes COX-2 activation.
- Leads to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.
- Can be used for research of Parkinson's disease, attention-deficit hyperactivity disorder, and Lesch-Nyhan syndrome.
- Decreases viability of Neuro-2a and SH-SY5Y cells in a concentration-dependent manner.
- Induces apoptosis and mitochondrial membrane depolarization in PC12 cells.
- Increases caspase-3, -8, and -9 activities.
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Medchemexpress LLC Dicyclomine hydrochloride | 67-92-5 | 98.1% | 100 MG
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Dicyclomine hydrochloride is a potent, orally active antagonist of muscarinic cholinergic receptors, showing high affinity for M1 (Ki=5.1 nM) and M2 (Ki=54.6 nM) subtypes. It acts as an antispasmodic agent, relieving smooth muscle spasms in the gastrointestinal tract in vivo.
- An orally active antagonist of muscarinic cholinergic receptors.
- Demonstrates high affinity for both M1 and M2 muscarinic receptor subtypes (Ki values: M1=5.1 nM, M2=54.6 nM).
- Functions as an antispasmodic agent.
- Relieves smooth muscle spasms in the gastrointestinal tract in vivo.
- May exacerbate cognitive impairments and lead to behavioral impairments in spatial tasks in animal models.
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Medchemexpress LLC Tracazolate hydrochloride | 1135210-68-2 | 99.24% | 50 MG
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Tracazolate hydrochloride is a potent GABAA receptor modulator, demonstrating selectivity for β3 and potentiating α1β1γ2s (EC50=13.2 μM) and α1β3γ2 (EC50=1.5 μM). Its potency is influenced by the nature of the third subunit within the receptor complex. This compound also exhibits anxiolytic and anticonvulsant properties.
- Potent GABAA receptor modulator
- Selectivity for β3
- Potentiates α1β1γ2s and α1β3γ2
- Possesses anxiolytic and anticonvulsant activity
- Interacts with GABAA receptors, adenosine receptors, and phosphodiesterases
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Medchemexpress LLC Mardepodect hydrochloride | 2070014-78-5 | 99.9% | C25H21ClN4O | 1 ML
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Mardepodect hydrochloride is a potent, orally active, and selective PDE10A inhibitor with an IC50 of 0.37 nM. It demonstrates over 1000-fold selectivity compared to other PDEs and can cross the blood-brain barrier. This product is for research use only and is not sold to patients.
- Potent, orally active, and selective PDE10A inhibitor
- >1000-fold selectivity over other PDEs
- Capable of crossing the blood-brain barrier
- Active in conditioned avoidance response assays (ED50 of 1 mg/kg)
- Administration to mice increases striatal cGMP dose-dependently
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Medchemexpress LLC 3-Aminophenylacetic acid | 14338-36-4 | 151.16 | 10 G
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3-Aminophenylacetic acid is an organic compound.
- It is an organic compound.
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Medchemexpress LLC Dioxopromethazine hydrochloride | 15374-15-9 | 99.97% | 352.88 | 1 ML
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Dioxopromethazine hydrochloride is an orally active antihistamine. It inhibits asthmatic symptoms and is suitable for relevant research.
- Inhibits asthmatic symptoms
- Orally active antihistamine
- Suitable for research applications
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Medchemexpress LLC Tropisetron Hydrochloride | 105826-92-4 | 99.97% | C17H21ClN2O2 | 1 ML
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Tropisetron Hydrochloride is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChR receptor agonist, with an IC50 of 70.1 nM for the 5-HT3 receptor. It possesses anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. It also reduces Ab-induced hippocampal neuroinflammation.
- Neuroprotective agent
- 5-HT3 receptor antagonist
- Calmodulin inhibitor
- Α7-nAChR receptor agonist
- Anti-inflammatory properties
- Immune-regulating functions
- Alleviates symptoms associated with chemotherapy and post-surgery
- Reduces Ab-induced hippocampal neuroinflammation
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Medchemexpress LLC 3-Methylazetidin-3-ol hydrochloride | 124668-46-8 | MFCD11100994 | ≥97.0% | C4H10ClNO | 50 G
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3-Methylazetidin-3-ol hydrochloride is a drug intermediate used for the synthesis of various active compounds. It is intended for research use only and not for patient use. This compound has a molecular weight of 123.58 and a chemical formula of C4H10ClNO, appearing as a white to off-white solid.
- Drug intermediate for synthesis of active compounds
- For research use only
- Solid appearance
- White to off-white color
- Purity of ≥97.0%
- Store at room temperature for 3 years
- In solvent, store at -80°C for 2 years or -20°C for 1 year
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Medchemexpress LLC Dalbavancin (hydrochloride) | 2227366-51-8 | 99.7% | 1853.15 | 1 ML
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Dalbavancin (hydrochloride) | 2227366-51-8 | 99.7% | 1853.15 | 1 ML
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Medchemexpress LLC Luvixasertib hydrochloride | 1610677-37-6 | 99.6% | 535.04 g/mol | C28H31ClN6O3 | 25 MG
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Luvixasertib hydrochloride is a selective, orally bioavailable TTK/Mps1 kinase inhibitor used in preclinical research to probe mitotic checkpoint function and to evaluate anticancer activity. It demonstrates potent in vitro inhibition of TTK and is supplied as a high-purity hydrochloride solid suitable for laboratory studies.
- Selective TTK/Mps1 kinase inhibition for targeted research.
- Potent in vitro activity (IC50 1.7 nM) for sensitive assays.
- Orally bioavailable profile applicable to in vivo models.
- Supplied as a hydrochloride solid with high purity for reproducible results.
- Stable when stored according to recommended conditions for research use.
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