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Filtered Search Results
Medchemexpress LLC 3,4-(Methylenedioxy)benzonitrile | 4421-09-4 | MFCD00005820 | 99.9% | 25g
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Piperonylonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]
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Medchemexpress LLC hsa-miR-21-5p inhibi 5nmol | 5nmol
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hsa-miR-21-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs The miRNA inhibitors have full-length nucleotide 2 -methoxy modification The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes thereby inhibiting miRNAs from functioning
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![eMolecules 7440-05-3 | Palladium, 1% on polyethylenimine/SiO? ROYER Pd CATALYST | Strem Chemicals | MFCD00011167 | 106.420 | Pd | 0.000 | [Pd] | 10g | 449079105](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000492793.jpg-250.jpg)
eMolecules 7440-05-3 | Palladium, 1% on polyethylenimine/SiO? ROYER Pd CATALYST | Strem Chemicals | MFCD00011167 | 106.420 | Pd | 0.000 | [Pd] | 10g | 449079105
Palladium, 1% on polyethylenimine/SiO? ROYER Pd CATALYST | Strem Chemicals | 7440-05-3 | MFCD00011167 | 106.420 | Pd | 0.000 | [Pd] | 10g | 449079105
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ILEX LIFE SCIENCES LLC Provis Biolabs rHA Recombinant Human Albumin Expressed in Pichia pastoris yeast 10 g 10 GR 1/EA
Provis Biolabs Recombinant Human Albumin (rHA) Expressed in Pichia pastoris Lyophilized Powder RUO Grade 10 g DESCRIPTION Provis Biolabs Recombinant Human Albumin (rHA) expressed in Pichia pastoris is a synthetic alternative to human serum albumin (HSA) The non-glycosylated polypeptide chain contains 585 amino acids and has a molecular mass of 67 kDa It does not contain any animal-derived components thus offering a reliable and sustainable alternative to traditional HSA sources Manufactured under ISO 9001 2015 Animal-origin-free (AOF) Research use only (RUO) GMP Grade is available upon request CAS 70024-90-7 SOURCE Protein is expressed in Pichia pastoris yeast (animal-free non-glycosylated) APPEARANCE An off-white to pale yellow powder PURITY 98% (SDS-PAGE HPLC) ENDOTOXIN 0 125 EU/mg STORAGE 2-8 C OPTIMAL CONCENTRATION (CELL CULTURE) 0 5 2 0 g/L MANUFACTURER Provis Biolabs pvt Ltd COUNTRY OF ORIGIN India
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Medchemexpress LLC Bromo-PEG2-C2-azide | 530151-56-5 | 98.7% | 5 G
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Bromo-PEG2-C2-azide is a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and also serves as a PEG-based PROTAC linker for PROTACs synthesis. It functions as a click chemistry reagent, containing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Non-cleavable ADC linker
- PEG-based PROTAC linker
- Click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- For research use only
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Cambridge Isotope Laboratories 2 2 4 4 5-PentaBDE (BDE-99) (13C12 99%) 50 ug/mL in nonane 1 2 mL
2 2 4 4 5-PentaBDE (BDE-99) (13C12 99%) 50 ug/mL in nonane 1 2 mL
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Medchemexpress LLC Undecylenate sodium 10g
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Undecylenate SodiumIt is an organic compound belonging to the class of carboxylates It is formed by the reaction of undecylenic acid and sodium hydroxide Undecylenate SodiumIt has a variety of applications in the cosmetic and personal care industries especially as an antifungal agent in products such as face creams lotions and shampoos In addition it can be used as a preservative in various formulations
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Medchemexpress LLC Polyethylene glycol 2000 | 25322-68-3 | MFCD00081839 | 2000.00 | H(OCH2CH2)nOH | 100g
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PEG2000 (Polyethylene glycol 2000) is a solvent for a large number of substances PEG2000 can be used as a carrier material and modifying agent PEG2000 is widely used in a variety of pharmaceutical formulations[1]
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Medchemexpress LLC KRAS G12C inhibitor 14 | 2349393-95-7 | 99.0% | 484.88 | C24H19ClF2N4O3 | 10MM 1ML
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KRAS G12C inhibitor 14 (Compound 17) is a potent small-molecule inhibitor selective for the KRAS G12C mutant (reported IC50 = 18 nM). It is supplied as a solid and as a 10 mM solution in DMSO for research use and is suitable for in vitro and in vivo studies of KRAS-driven signaling.
- Potency: IC50 = 18 nM against KRAS G12C.
- Molecular formula: C24H19ClF2N4O3; molecular weight: 484.88 g/mol.
- Purity: 99.0%.
- Available formats: solid (1 mg-500 mg) and 10 mM, 1 mL solution in DMSO.
- Solubility: DMSO 100 mg/mL; in vivo formulation yields ≥9 mg/mL in 10% DMSO/40% PEG300/5% Tween-80/45% saline.
- Storage: solid at -20°C; stock solution -80°C (6 months) or -20°C (1 month); protect from light and avoid repeated freeze-thaw.
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Medchemexpress LLC PD-L1 Human CHO F 10ug
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PD-L1 Protein Human (CHO Fc) play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy tissue allografts autoimmune disease and other disease states such as hepatitis
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Medchemexpress LLC Quinotolast sodium | 101193-62-8 | MFCD31382142 | 371.31 | 1 ML
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Quinotolast sodium (FR71021) is a histamine receptor inhibitor that concentration-dependently inhibits histamine, LTC4, and PGD2 release within the range of 1-100 μg/mL. It significantly inhibits inflammatory mediators from human dispersed lung cells and demonstrates strong inhibitory effects on histamine and peptide leukotrienes release from guinea pig lung fragments or mouse cultured mast cells.
- Inhibits histamine, LTC4, and PGD2 release.
- Significantly inhibits inflammatory mediators.
- Potently inhibits type I allergic reactions.
- Effective via intravenous and oral dosing.
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Medchemexpress LLC OT-82 | 1800487-55-1 | 99.95% | 424.47 | 10 MG
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OT-82 is a potent, selective, and orally active inhibitor of NAMPT. It is selectively toxic to cells of hematopoietic origin and induces cell death in a NAD+ dependent manner. It is a promising antineoplastic agent for the study of hematological malignancies.
- Potent, selective, and orally active NAMPT inhibitor
- Selectively toxic to cells of hematopoietic origin
- Induces cell death in a NAD+ dependent manner
- Promising antineoplastic agent
- Demonstrates tissue-selective cytotoxicity
- Inhibits recombinant NAMPT activity
- Reduces cellular NAD and ATP concentrations
- Activates caspase-3 and increases sub-G1 DNA content
- Depolarizes the mitochondrial membrane
- Increases survival in a SC xenograft model of Burkitt's lymphoma
- Potently inhibits tumor growth in a multiple myeloma mouse model
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Medchemexpress LLC Maltodextrin | 9050-36-6 | MFCD00146679 | Variable (no fixed molecular weight; polymeric - represented as (C6H10O5)n·xH2O) | (C6H10O5)n·xH2O | 100 G
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Maltodextrin, dextrose equivalent 16.5-19.5 is a water-soluble polysaccharide used as an excipient and formulation aid in research applications. It provides intermediate hydrolysis (DE 16.5-19.5) and is supplied as a white to off-white powder for laboratory use.
- Water-soluble excipient for stabilization and encapsulation.
- Intermediate dextrose equivalent for balanced solubility and viscosity.
- Forms nanoparticles with narrow size distribution for delivery studies.
- Non-toxic at tested concentrations in cell assays.
- Available in common laboratory pack sizes for research use.
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Apexbio Technology LLC Regorafenib hydrochloride(Synonyms: Regorafenib HCl, BAY 73-4506, Stivarga, BAY73-4506 hydrochloride, Regorafenib hydrochloride salt), 10mM (in 1mL DMSO), CAS: 835621-07-3.
Regorafenib hydrochloride (CAS 835621-07-3) is an orally bioavailable small molecule inhibitor targeting multiple protein kinases including c-KIT VEGFR2 and B-Raf It inhibits these kinases with IC50 values of approximately 17 nM (c-KIT) 40 nM (VEGFR2) and 69 nM (B-Raf) By blocking kinase signaling Regorafenib hydrochloride effectively interrupts tumor-associated pathways involved in cell proliferation angiogenesis and survival It is widely used in oncology research for studies focused on kinase-mediated tumor growth and vascularization mechanisms
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Medchemexpress LLC Oxalyldihydrazide | 996-98-5 | 98.0% | 118.09 | 100 G
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Oxalyldihydrazide is a crosslinking agent used in proteomics research. It can capture carbonylated proteins on the surface of a microchip. It is for research use only and not sold to patients.
- Crosslinking agent in proteomics research.
- Can capture carbonylated proteins on the surface of a microchip.
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