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Filtered Search Results
Medchemexpress LLC Tetrahydrozoline hydrochloride | 522-48-5 | 99.88% | 5 G
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Tetrahydrozoline hydrochloride, also known as Tetryzoline hydrochloride, is an α-adrenergic agonist that induces vasoconstriction. It is commonly used in research concerning nasal and conjunctival congestion. This compound also promotes the synthesis of collagen types I and III in primary human gingival fibroblasts in vitro.
- Acts as an α-adrenergic agonist causing vasoconstriction.
- Utilized in research for nasal and conjunctival congestion.
- Induces collagen types I and III synthesis in human gingival fibroblasts.
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Medchemexpress LLC Tetrahydrozoline hydrochloride | 522-48-5 | 99.9% | 1 G
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Tetrahydrozoline hydrochloride, also known as Tetryzoline hydrochloride, is an imidazoline derivative. It acts as an α-adrenergic agonist, leading to vasoconstriction. This compound is frequently utilized in research studies focusing on nasal congestion and conjunctival congestion.
- Functions as an α-adrenergic agonist.
- Induces vasoconstriction.
- Used in research for nasal and conjunctival congestion.
- High purity (99.88%).
- Appears as a white to off-white solid.
- Exhibits good solubility in water and DMSO.
- Induces collagen types I and III synthesis in primary human gingival fibroblasts in vitro.
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Medchemexpress LLC Olopatadine hydrochloride | 140462-76-6 | 99.8% | 50 MG
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Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis and other allergic disorders. It significantly inhibits ear swelling and the production of several interleukins. It is rapidly absorbed, with renal clearance, and has shown effectiveness in treating allergic rhinitis and chronic urticaria in clinical trials.
- Used to treat allergic conjunctivitis
- Second-generation histamine H1 receptor antagonist
- Significantly inhibits ear swelling
- Increases production of IL-4, IL-1beta, IL-6, GM-CSF, and NGF
- Highly and rapidly absorbed in healthy human volunteers
- Renal clearance drug
- Useful for treating allergic rhinitis and chronic urticaria
- Inhibits histamine release from human conjunctival mast cells
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Medchemexpress LLC Cefmenoxime hydrochloride | 75738-58-8 | 99.29% | 500 MG
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Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic that demonstrates antibacterial activity against a wide variety of gram-positive and gram-negative bacteria.
- Inhibits at least 90% of tested strains (MIC90) ranging from 0.06 to 8 μg/mL for Enterobacteriaceae.
- MIC90 values for gram-positive cocci are 0.015 and ≤0.008 μg/mL for Streptococcus pneumoniae and Streptococcus pyogenes, respectively, and 2 μg/mL for S. aureus.
- Exhibits activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis with MIC90 values from ≤0.008 to 0.25 μg/mL.
- Improved the survival rate of mice infected with lung bacteria in in vivo studies.
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Medchemexpress LLC Cefmenoxime (hydrochloride) | 75738-58-8 | 99.3% | 1 G
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Cefmenoxime hydrochloride is a new semisynthetic cephalosporin antibiotic, effective against a wide range of gram-positive and gram-negative bacteria.
- Molecular weight: 529.79
- Chemical formula: C16H17.5Cl0.5N9O5S3
- Appearance: White to yellow solid
- Storage: 4°C, sealed, away from moisture
- In solvent storage: -80°C for 6 months; -20°C for 1 month
- Soluble in DMSO (65 mg/mL), insoluble in water
- Inhibits at least 90% of tested strains (MIC90) from 0.06 to 8 μg/mL for Enterobacteriaceae
- Effective against Haemophilus influenzae, Neisseria gonorrhoeae, and Neisseria meningitidis
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Medchemexpress LLC PF-06815345 hydrochloride | 2334434-49-8 | 98.2% | 634.49 | 100 MG
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PF-06815345 hydrochloride is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. PF-06815345 hydrochloride significantly decreases the PCSK9 level in vivo in mouse.
- Orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9).
- IC50 value of 13.4 μM.
- Significantly decreases the PCSK9 level in vivo in mouse.
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Medchemexpress LLC PF-00356231 hydrochloride | 820223-77-6 | 99.5% | 464.96 | 25 MG
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PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). It forms a complex with MMP-12 and also demonstrates potency against MMP-13, MMP-8, MMP-9, and MMP-3.
- Specific inhibitor of MMP-12
- Non-peptidic, non-zinc chelating ligand
- Potent against MMP-13, MMP-8, MMP-9, and MMP-3
- For research use only
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Medchemexpress LLC 3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) | 3722-51-8 | 98.4% | 212.20 | 50 G
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3-Hydroxyxanthone is a xanthone compound. It inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs) and also inhibits TNF-alpha induced ICAM-1 expression.
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Medchemexpress LLC Pilsicainide hydrochloride | 88069-49-2 | 99.9% | 308.85 | C17H25ClN2O | 5 MG
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Pilsicainide hydrochloride is an orally active sodium channel blocker used in research on cardiac electrophysiology. It functions as a potent class Ic antiarrhythmic agent and is provided as a solid suitable for laboratory studies.
- Orally active sodium channel blocker.
- Potent class Ic antiarrhythmic agent.
- High purity (99.94%).
- White to off-white solid appearance.
- Available in small-mass packages for analytical and pharmacological work.
- Stable when stored under recommended conditions.
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Medchemexpress LLC MRS 2211 sodium hydrate | 1197030-56-0 | MFCD09038558 | 97.9% | 470.69 g/mol | C14H13ClN4NaO9P | 5 MG
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MRS 2211 sodium hydrate is the sodium salt hydrate form of a selective competitive P2Y13 receptor antagonist supplied for research use. It is provided as a brown to reddish-brown solid with reported purity of 97.9%, intended for in vitro pharmacology and biochemical studies of purinergic signaling.
- Selective P2Y13 receptor antagonism (pIC50 ≈ 5.97).
- High reported purity for reliable experimental results.
- Solid form suitable for dissolution and formulation in common solvents.
- Available in small quantities for exploratory and pilot studies.
- Recommended sealed, cold storage to minimize degradation.
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![Medchemexpress LLC 2-[2-[2-(5-bromo-2-methoxyphenyl)ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole hydrochloride | 1706524-94-8 | MFCD28133377 | 99.3% | 413.71 g·mol⁻¹ | C18H19BrClFN2O | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263559.png-250.jpg)
Medchemexpress LLC 2-[2-[2-(5-bromo-2-methoxyphenyl)ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole hydrochloride | 1706524-94-8 | MFCD28133377 | 99.3% | 413.71 g·mol⁻¹ | C18H19BrClFN2O | 5 MG
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ML-00253764 hydrochloride is the hydrochloride salt of a brain-penetrant, nonpeptidic antagonist of the melanocortin 4 receptor (MC4R) used in pharmacological research. It exhibits submicromolar binding and functional inhibition of MC4R, is supplied as a high-purity solid, and is intended for in vitro and in vivo studies when handled and stored according to manufacturer recommendations.
- Brain-penetrant, nonpeptidic melanocortin 4 receptor (MC4R) antagonist.
- Submicromolar potency: Ki = 0.16 μM, IC50 = 0.103 μM.
- High purity (~99.3%) suitable for research applications.
- Hydrochloride salt form for improved handling and solubility.
- Solid, off-white to light yellow appearance; easy to weigh and formulate.
- Recommended for in vitro and in vivo pharmacology with proper storage.
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Medchemexpress LLC Hdac10-in-2 hydrochloride | 95.0% | C19H23ClN2O2 | 50 MG
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HDAC10-IN-2 hydrochloride is a potent and highly selective HDAC10 inhibitor with an IC50 of 20 nM. It modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells.
- Potent and highly selective HDAC10 inhibitor.
- IC50 of 20 nM for drHDAC10.
- Modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells.
- For research use only.
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Medchemexpress LLC Tiviciclovir hydrochloride | 00-00-0 | 99.4% | 275.69 g/mol | C9H14ClN5O3 | 5 MG
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Tiviciclovir hydrochloride is an antiviral guanosine analog used as a hepatitis B virus (HBV) inhibitor in preclinical research. It is supplied as the hydrochloride salt, with molecular formula C9H14ClN5O3 and molecular weight 275.69 g/mol. The product listing and datasheet include solubility, formulation guidance, storage recommendations, and batch-specific purity information for laboratory use.
- Has antiviral activity against hepatitis B virus.
- Provided as a hydrochloride salt to aid solubility.
- Soluble in DMSO at 100 mg/mL; ultrasonic aid recommended.
- Formulation guidance for in vivo dosing is included.
- Storage recommendations for dry material and solutions are provided.
- Includes batch-specific certificate of analysis indicating high purity.
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Medchemexpress LLC Amitifadine hydrochloride | 410074-74-7 | MFCD26405807 | 99.6% | 264.58 g/mol | C11H12Cl3N | 10 MG
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Amitifadine hydrochloride is a small-molecule serotonin-norepinephrine-dopamine reuptake inhibitor supplied as a solid research reagent for in vitro and preclinical studies. It is intended for laboratory research use only.
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Ambeed 11bS N NDiethyldinaphtho 2 1d
(11bS)-N,N-Diethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine, 252288-04-3, 98% 99%ee
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